标签归档：vip

[(4Cl)DPhe6,Leu17]-VIP 品牌：Anygen

发表于由

[(4Cl)DPhe6,Leu17]-VIP

品牌：Anygen
CAS No.：
储存条件：-20℃
纯度：–
产品编号

(生产商编号)

 等级 规格 运输包装 零售价(RMB) 库存情况 参考值

303-91031

 – 0.5 mg – 咨询 – –


* 干冰运输、大包装及大批量的产品需酌情添加运输费用


* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动，恕不另行通知，确切详情请联系上海金畔生物科技有限公司。

Prepro VIP (111-122), human

发表于由

Prepro VIP (111-122), human;

Prepro VIP (111-122), human 是一种前体血管活性肠肽 (VIP) 的衍生肽，对应其 111-122 残基氨基酸序列。血管活性肠肽存在于周围和中枢神经系统中，作为一种非镇静、非胆碱能神经递质或神经调节剂发挥作用。

Prepro VIP (111-122), humanamp;;

Prepro VIP (111-122), human Chemical Structure

CAS No. : 123025-94-5

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

Prepro VIP (111-122), human is a prepro-vasoactive intestinal polypeptide (VIP)–derived peptide, corresponding to residues 111-122. VIP is present in the peripheral and the central nervous systems where it functions as a nonadrenergic, noncholinergic neurotransmitter or neuromodulator[1][2].

分子量

1242.33

Formula

C53H87N13O21
CAS 号

123025-94-5
Sequence

Val-Ser-Ser-Asn-Ile-Ser-Glu-Asp-Pro-Val-Pro-Val
Sequence Shortening

VSSNISEDPVPV
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Bredkjaer HE, et al. Location of PHM/VIP mRNA in human gastrointestinal tract detected by in situ hybridization. Cell Tissue Res. 1994 May;276(2):229-38.

    [2]. Henning RJ, et al. Vasoactive intestinal peptide: cardiovascular effects. Cardiovasc Res. 2001 Jan;49(1):27-37.

VIP(Guinea pig) TFA(Synonyms: Vasoactive Intestinal Peptide, guinea pig TFA)

发表于由

VIP(Guinea pig) TFA;(Synonyms: Vasoactive Intestinal Peptide, guinea pig TFA)

VIP Guinea pig TFA (Vasoactive intestinal peptide) 是一种营养和有丝分裂因子，可刺激胚胎生长。VIP Guinea pig 是一种简单的胃肠激素，具有神经递质的功能。

VIP(Guinea pig) TFAamp;;(Synonyms: Vasoactive Intestinal Peptide, guinea pig TFA)

VIP(Guinea pig) TFA Chemical Structure

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

VIP Guinea pig TFA (Vasoactive intestinal peptide), a trophic and mitogenic factor, stimulates growth in whole cultured embryos. VIP Guinea pig functions as a simple gastrointestinal hormone and suggest a possible neurotransmitter function[1][2].

体外研究
(In Vitro)

Vasoactive intestinal peptide (10(-7)M) shortened S phase and G1 phase of neuroepithelial cells by 50% (4.8-2.4 h) and 58% (1.9-0.8 h), respectively, compared with controls[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

3458.88

Formula

C147H239N43O42S2.C2HF3O2
Sequence

His-Ser-Asp-Ala-Leu-Phe-Thr-Asp-Thr-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Met-Lys-Lys-Tyr-Leu-Asn-Ser-Val-Leu-Asn-NH2
Sequence Shortening

HSDALFTDTYTRLRKQMAMKKYLNSVLN-NH2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. P Gressens, et al. Vasoactive intestinal peptide shortens both G1 and S phases of neural cell cycle in whole postimplantation cultured mouse embryos. Eur J Neurosci. 1998 May;10(5):1734-42.

    [2]. M G Bryant, et al. Possible dual role for vasoactive intestinal peptide as gastrointestinal hormone and neurotransmitter substance. Lancet. 1976 May 8;1(7967):991-3.

Prepro VIP (81-122), human

发表于由

Prepro VIP (81-122), human;

Prepro VIP (81-122), human 是一种前体血管活性肠肽 (VIP) 的衍生肽，对应其 81-122 残基氨基酸序列。肽组氨酸-缬氨酸 42 (PHV-42) 已被指定与 Prepro VIP (81-122) 完全对应，它可降低离体大鼠子宫自发收缩的力和频率。

Prepro VIP (81-122), humanamp;;

Prepro VIP (81-122), human Chemical Structure

CAS No. : 111366-38-2

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

Prepro VIP (81-122), human is a prepro-vasoactive intestinal polypeptide (VIP) derived peptide, corresponding to residues 81-122. Peptide histidine valine 42 (PHV-42) has been designated to correspond exactly to Prepro VIP (81-122), which reduces both the force and frequency of spontaneous contractions of isolated rat uterus[1].

分子量

4552.13

Formula

C202H325N53O64S
CAS 号

111366-38-2
Sequence

His-Ala-Asp-Gly-Val-Phe-Thr-Ser-Asp-Phe-Ser-Lys-Leu-Leu-Gly-Gln-Leu-Ser-Ala-Lys-Lys-Tyr-Leu-Glu-Ser-Leu-Met-Gly-Lys-Arg-Val-Ser-Ser-Asn-Ile-Ser-Glu-Asp-Pro-Val-Pro-Val
Sequence Shortening

HADGVFTSDFSKLLGQLSAKKYLESLMGKRVSSNISEDPVPV
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Yiangou Y, et al. Isolation, characterization, and pharmacological actions of peptide histidine valine 42, a novelprepro-vasoactive intestinal peptide-derived peptide. J Biol Chem. 1987 Oct 15;262(29):14010-3.

[D-p-Cl-Phe6,Leu17]-VIP

发表于由

[D-p-Cl-Phe6,Leu17]-VIP;

[D-p-Cl-Phe6,Leu17]-VIP 是一种竞争性和选择性的血管活性肠肽 (VIP) 受体拮抗剂，IC50 值为 125.8 nM。[D-p-Cl-Phe6,Leu17]-VIP 对胰高血糖素，促胰液素和 GRF 受体无活性。

[D-p-Cl-Phe6,Leu17]-VIPamp;;

[D-p-Cl-Phe6,Leu17]-VIP Chemical Structure

CAS No. : 102805-45-8

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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[D-p-Cl-Phe6,Leu17]-VIP 的其他形式现货产品:

[D-p-Cl-Phe6,Leu17]-VIP TFA

生物活性

[D-p-Cl-Phe6,Leu17]-VIP is a competitive and selective antagonist of vasoactive intestinal peptide (VIP) receptor, with the IC50 of 125.8 nM. [D-p-Cl-Phe6,Leu17]-VIP has no activity on glucagon, secretin or GRF receptors[1][2][3].

IC50 Target

IC50: 125.8 nM (VIP receptor)[1]
分子量

3342.20

Formula

C148H239ClN44O42
CAS 号

102805-45-8
Sequence

His-Ser-Asp-Ala-Val-{Cl-Phe}-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Leu-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH2
Sequence Shortening

HSDAV-{Cl-Phe}-TDNYTRLRKQLAVKKYLNSILN-NH2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. Pozo D, et, al. Characterization of VIP receptor-effector system antagonists in rat and mouse peritoneal macrophages. Eur J Pharmacol. 1997 Mar 5; 321(3): 379-86.

    [2]. Pandol SJ, et, al. Vasoactive intestinal peptide receptor antagonist [4Cl-D-Phe6, Leu17] VIP. Am J Physiol. 1986 Apr; 250 (4 Pt 1): G553-7.

    [3]. Messmer B, et, al. Regulation of exocrine pancreatic secretion by cerebral TRH and CGRP: role of VIP, muscarinic, and adrenergic pathways. Am J Physiol. 1993 Feb; 264(2 Pt 1): G237-42.

[D-p-Cl-Phe6,Leu17]-VIP TFA

发表于由

[D-p-Cl-Phe6,Leu17]-VIP TFA; 纯度: 99.26%

[D-p-Cl-Phe6,Leu17]-VIP TFA 是一种竞争性和选择性的血管活性肠肽 (VIP) 受体拮抗剂，IC50 值为 125.8 nM。[D-p-Cl-Phe6,Leu17]-VIP TFA 对胰高血糖素，促胰液素和 GRF 受体无活性。

[D-p-Cl-Phe6,Leu17]-VIP TFAamp;;

[D-p-Cl-Phe6,Leu17]-VIP TFA Chemical Structure

规格 价格 是否有货 数量
5 mg ￥5500 In-stock
10 mg ￥9500 In-stock
50 mg ; 询价 ;
100 mg ; 询价 ;

* Please select Quantity before adding items.

[D-p-Cl-Phe6,Leu17]-VIP TFA 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus
  • Peptide Library

生物活性

[D-p-Cl-Phe6,Leu17]-VIP TFA is a competitive and selective antagonist of vasoactive intestinal peptide (VIP) receptor, with the IC50 of 125.8 nM. [D-p-Cl-Phe6,Leu17]-VIP TFA has no activity on glucagon, secretin or GRF receptors[1][2][3].

IC50 Target

IC50: 125.8 nM (VIP receptor)[1]
分子量

3456.22

Formula

C150H240F3ClN44O44
Sequence

His-Ser-Asp-Ala-Val-{Cl-Phe}-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Leu-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH2
Sequence Shortening

HSDAV-{Cl-Phe}-TDNYTRLRKQLAVKKYLNSILN-NH2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Sealed storage, away from moisture

Powder -80deg;C 2 years
-20deg;C 1 year

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture)
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. Pozo D, et, al. Characterization of VIP receptor-effector system antagonists in rat and mouse peritoneal macrophages. Eur J Pharmacol. 1997 Mar 5; 321(3): 379-86.

    [2]. Pandol SJ, et, al. Vasoactive intestinal peptide receptor antagonist [4Cl-D-Phe6, Leu17] VIP. Am J Physiol. 1986 Apr; 250 (4 Pt 1): G553-7.

    [3]. Messmer B, et, al. Regulation of exocrine pancreatic secretion by cerebral TRH and CGRP: role of VIP, muscarinic, and adrenergic pathways. Am J Physiol. 1993 Feb; 264(2 Pt 1): G237-42.

PHM-VIP Space Peptide (PHM (111-122) / Prepro VIP) 品牌：Anygen

发表于由

PHM-VIP Space Peptide (PHM (111-122) / Prepro VIP)

品牌：Anygen
CAS No.：
储存条件：-20℃
纯度：–
产品编号

(生产商编号)

 等级 规格 运输包装 零售价(RMB) 库存情况 参考值

301-91071

 – 0.5 mg – 咨询 – –


* 干冰运输、大包装及大批量的产品需酌情添加运输费用


* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动，恕不另行通知，确切详情请联系上海金畔生物科技有限公司。

Vasoactive Intestinal Peptide (VIP) Antagonist 品牌：Anygen

发表于由

Vasoactive Intestinal Peptide (VIP) Antagonist

品牌：Anygen
CAS No.：
储存条件：-20℃
纯度：–
产品编号

(生产商编号)

 等级 规格 运输包装 零售价(RMB) 库存情况 参考值

303-37051

 – 0.5 mg – 咨询 – –


* 干冰运输、大包装及大批量的产品需酌情添加运输费用


* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动，恕不另行通知，确切详情请联系上海金畔生物科技有限公司。

PHM (156-170) (Prepro VIP) 品牌：Anygen

发表于由

PHM (156-170) (Prepro VIP)

品牌：Anygen
CAS No.：
储存条件：-20℃
纯度：–
产品编号

(生产商编号)

 等级 规格 运输包装 零售价(RMB) 库存情况 参考值

308-91081

 – 0.5 mg – 咨询 – –


* 干冰运输、大包装及大批量的产品需酌情添加运输费用


* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动，恕不另行通知，确切详情请联系上海金畔生物科技有限公司。

Anti VIP, Rabbit 品牌：Peptide

发表于由

Anti VIP, Rabbit

品牌：Peptide
CAS No.：
储存条件：-20℃
纯度：–
产品编号

(生产商编号)

 等级 规格 运输包装 零售价(RMB) 库存情况 参考值

334-00011

 – 50uL – 咨询 – –


* 干冰运输、大包装及大批量的产品需酌情添加运输费用


* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动，恕不另行通知，确切详情请联系上海金畔生物科技有限公司。