Ramucirumab(Synonyms: 雷莫芦单抗)

Ramucirumab;(Synonyms: 雷莫芦单抗) 纯度: 99.40%

Ramucirumab 是人 VEGFR-2 拮抗剂,具有抗实体瘤作用。Ramucirumab 是一种人源化单克隆抗体,可与 VEGFR-2 结合,阻止 VEGFR 配体 VEGF-A,VEGF-C 和 VEGF-D 结合。

Ramucirumabamp;;(Synonyms: 雷莫芦单抗)

Ramucirumab Chemical Structure

CAS No. : 947687-13-0

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生物活性

Ramucirumab is a human VEGFR-2 antagonist for the treatment of solid tumors[1]. Ramucirumab is a recombinant human immunoglobulin G1 monoclonal antibody that binds to the extracellular binding domain of VEGFR-2 and prevents the binding of VEGFR ligands: VEGF-A, VEGF-C, and VEGF-D[2].

IC50 Target[1][2]

VEGFR-2

;

Clinical Trial

分子量

143609.63

Formula

C6374H9864N1692O1996S46

CAS 号

947687-13-0

中文名称

雷莫芦单抗

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Fala L. Cyramza (Ramucirumab) Approved for the Treatment of Advanced Gastric Cancer and Metastatic Non-Small-Cell Lung Cancer. Am Health Drug Benefits. 2015 Mar;8(Spec Feature):49-53.

    [2]. Oholendt AL, et al. Ramucirumab: A New Therapy for Advanced Gastric Cancer. J Adv Pract Oncol. 2015 Jan-Feb;6(1):71-5.

BTN-KDR(VEGFR2) 品牌:Carna Bio


BTN-KDR(VEGFR2)

品牌:Carna Bio
CAS No.:
储存条件:-80℃
纯度:
产品编号

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387-01841

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