Deoxycytidine triphosphate trisodium salt(Synonyms: dCTP trisodium salt; 2′-Deoxycytidine-5′-triphosphate trisodium salt)

生化分析试剂 Biochemical Assay Reagents
Deoxycytidine triphosphate trisodium salt;(Synonyms: dCTP trisodium salt; 2′-Deoxycytidine-5′-triphosphate trisodium salt) 纯度: ge;97.0%

Deoxycytidine triphosphate trisodium salt (dCTP trisodium salt) 是可用于 DNA 合成 (DNA synthesis) 的核苷三磷酸。Deoxycytidine triphosphate trisodium salt 可用于实时 PCR,cDNA 合成 和 DNA 测序等研究。

Deoxycytidine triphosphate trisodium salt(Synonyms: dCTP trisodium salt; 2′-Deoxycytidine-5′-triphosphate trisodium salt)

Deoxycytidine triphosphate trisodium salt Chemical Structure

CAS No. : 109909-44-6

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生物活性

Deoxycytidine triphosphate trisodium salt (dCTP trisodium salt) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate trisodium salt has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing[1][2][3].

体外研究
(In Vitro)

Assays of thirteen cell lines, derived from mouse lymphomas, myelomas, myeloid tumors, and a mastocytoma, for sensitivity to growth inhibition by 1-β-D-arabinofuranosylcytosine (ara-C) revealed a spectrum between the most and least sensitive which differed 100-fold from each other. An inverse correlation between sensitivity and cellular Deoxycytidine triphosphate (2′-Deoxycytidine-5′-triphosphate, dCTP) content is found, and this suggested that sensitivity of cells might be increased if the dCTP content was lowered during cell exposure to ara-C[1].
Deoxycytidine triphosphate trisodium salt is a phosphoethanolamine cytidylyltransferase substrate[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

533.10

Formula

C9H13N3Na3O13P3

CAS 号

109909-44-6

中文名称

脱氧胞苷三磷酸三钠盐;2′-脱氧胞苷-5′-三磷酸三钠盐

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4deg;C, sealed storage, away from moisture

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture)

溶解性数据
In Vitro:;

H2O : 250 mg/mL (468.96 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.8758 mL 9.3791 mL 18.7582 mL
5 mM 0.3752 mL 1.8758 mL 3.7516 mL
10 mM 0.1876 mL 0.9379 mL 1.8758 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

参考文献
  • [1]. A W Harris, et al. Effect of thymidine on the sensitivity of cultured mouse tumor cells to 1-beta-D-arabinofuranosylcytosine. Cancer Res. 1979 Feb;39(2 Pt 1):538-41.

    [2]. B A Bladergroen, et al. CTP:phosphoethanolamine cytidylyltransferase. Biochim Biophys Acta. 1997 Sep 4;1348(1-2):91-9.

    [3]. M H Tattersall, et al. Deoxyribonucleoside triphosphates in human cells: changes in disease and following exposure to drugs. Eur J Clin Invest. 1975 Apr;5(2):191-202.

Deoxyguanosine triphosphate trisodium salt(Synonyms: dGTP trisodium salt; 2′-Deoxyguanosine-5′-triphosphate trisodium salt)

生化分析试剂 Biochemical Assay Reagents
Deoxyguanosine triphosphate trisodium salt;(Synonyms: dGTP trisodium salt; 2′-Deoxyguanosine-5′-triphosphate trisodium salt) 纯度: 99.15%

Deoxyguanosine triphosphate (dGTP) trisodium salt 是细胞中用于 DNA 合成的核苷酸前体。Deoxyguanosine triphosphate trisodium salt 用于逆转录聚合酶链反应 (RT-PCR) 中以进行 DNA 扩增。

Deoxyguanosine triphosphate trisodium salt(Synonyms: dGTP trisodium salt; 2

Deoxyguanosine triphosphate trisodium salt Chemical Structure

CAS No. : 93919-41-6

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25mg (100 mM * 440 μL in Water) ¥700 In-stock
50mg (100 mM * 880 μL in Water) ¥1000 In-stock

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生物活性

Deoxyguanosine triphosphate (dGTP) trisodium salt is a nucleotide precursor in cells for DNA synthesis. Deoxyguanosine triphosphate trisodium salt is used in reverse transcription-polymerase chain reaction (RT-PCR) for DNA amplification[1].

分子量

573.13

Formula

C10H13N5Na3O13P3

CAS 号

93919-41-6

中文名称

2′-脱氧鸟苷-5′-三磷酸三钠盐

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Solution, -20deg;C, 2 years

溶解性数据
In Vitro:;

H2O : 66.67 mg/mL (116.33 mM; Need ultrasonic)

DMSO : < 1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble or slightly soluble)

参考文献
  • [1]. Marco Gatti, et al. The Ubiquitin Ligase TRIP12 Limits PARP1 Trapping and Constrains PARP Inhibitor Efficiency. Cell Rep. 2020 Aug 4;32(5):107985.

2′-Deoxyadenosine-5′-triphosphate trisodium(Synonyms: dATP trisodium)

生化分析试剂 Biochemical Assay Reagents
2′-Deoxyadenosine-5′-triphosphate trisodium;(Synonyms: dATP trisodium) 纯度: ge;98.0%

2′-Deoxyadenosine-5′-triphosphate trisodium (dATP trisodium) 是一种核苷酸,在细胞中用于 DNA 合成或复制。2′-Deoxyadenosine-5′-triphosphate (dATP) 是 DNA 聚合酶的底物。

2

2′-Deoxyadenosine-5′-triphosphate trisodium Chemical Structure

CAS No. : 54680-12-5

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生物活性

2′-Deoxyadenosine-5′-triphosphate trisodium (dATP trisodium) is a nucleotide used in cells for DNA synthesis (or replication), as a substrate of DNA polymerase[1].

Clinical Trial

分子量

557.13

Formula

C10H13N5Na3O12P3

CAS 号

54680-12-5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4deg;C, sealed storage, away from moisture and light

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture and light)

溶解性数据
In Vitro:;

H2O : 250 mg/mL (448.73 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.7949 mL 8.9746 mL 17.9491 mL
5 mM 0.3590 mL 1.7949 mL 3.5898 mL
10 mM 0.1795 mL 0.8975 mL 1.7949 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

参考文献
  • [1]. P J Romaniuk, A study of the mechanism of T4 DNA polymerase with diastereomeric phosphorothioate analogues of deoxyadenosine triphosphate. J Biol Chem. 1982 Jul 10;257(13):7684-8.

Fosfructose trisodium(Synonyms: Diphosphofructose trisodium; Esafosfan trisodium; FDP trisodium)

天然产物 糖类和糖苷 Saccharides and Glycosides

Fosfructose trisodium;(Synonyms: Diphosphofructose trisodium; Esafosfan trisodium; FDP trisodium) 纯度: ge;99.0%

Fosfructose trisodium (Diphosphofructose trisodium) 是一种细胞保护性的天然糖磷酸盐,用于心血管缺血,镰状细胞性贫血和哮喘的研究。 它通过刺激无氧糖酵解起作用,其在缺血条件下产生三磷酸腺苷。

Fosfructose trisodium(Synonyms: Diphosphofructose trisodium; Esafosfan trisodium; FDP trisodium)

Fosfructose trisodium Chemical Structure

CAS No. : 38099-82-0

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生物活性

Fosfructose trisodium (Diphosphofructose trisodium;Esafosfan trisodium;FDP trisodium) is a cytoprotective natural sugar phosphate for the potential treatment of cardiovascular ischemia, sickle cell anemia and asthma. It acts by stimulating anaerobic glycolysis which generates adenosine triphosphate under ischemic conditions.

IC50 Target

Endogenous Metabolite[1]

分子量

406.06

Formula

C6H11Na3O12P2

CAS 号

38099-82-0

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

-20deg;C, sealed storage, away from moisture

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture)

溶解性数据
In Vitro:;

H2O : 150 mg/mL (369.40 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.4627 mL 12.3135 mL 24.6269 mL
5 mM 0.4925 mL 2.4627 mL 4.9254 mL
10 mM 0.2463 mL 1.2313 mL 2.4627 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

参考文献
  • [1]. Folkesson HG, et al. Fosfructose (Questcor). IDrugs. 2001 Dec;4(12):1401-7.

Deoxythymidine-5′-triphosphate trisodium(Synonyms: 脱氧胸苷三磷酸三钠盐; dTTP trisodium)

生化分析试剂 Biochemical Assay Reagents
Deoxythymidine-5′-triphosphate trisodium;(Synonyms: 脱氧胸苷三磷酸三钠盐; dTTP trisodium) 纯度: ge;98.0%

Deoxythymidine-5′-triphosphate (dTTP) trisodium 是四种核苷三磷酸之一,可以合成 DNA。

Deoxythymidine-5

Deoxythymidine-5′-triphosphate trisodium Chemical Structure

CAS No. : 27821-54-1

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生物活性

Deoxythymidine-5′-triphosphate (dTTP) trisodium is one of the four nucleoside triphosphates used in the synthesis of DNA[1].

IC50 Target

Human Endogenous Metabolite

;

Clinical Trial

分子量

548.11

Formula

C10H14N2Na3O14P3

CAS 号

27821-54-1

中文名称

脱氧胸苷三磷酸三钠盐

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4deg;C, sealed storage, away from moisture and light

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture and light)

溶解性数据
In Vitro:;

H2O : 250 mg/mL (456.11 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.8245 mL 9.1223 mL 18.2445 mL
5 mM 0.3649 mL 1.8245 mL 3.6489 mL
10 mM 0.1824 mL 0.9122 mL 1.8245 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

参考文献
  • [1]. Bruce Stillman, et al. Deoxynucleoside triphosphate (dNTP) synthesis and destruction regulate the replication of both cell and virus genomes. Proc Natl Acad Sci U S A.2013 Aug 27;110(35):14120-1.

Cytidine 5′-diphosphate trisodium salt(Synonyms: CDP)

天然产物 糖类和糖苷 Saccharides and Glycosides

Cytidine 5′-diphosphate trisodium salt;(Synonyms: CDP) 纯度: ge;98.0%

Cytidine 5′-diphosphate trisodium salt (CDP) 是由尿苷单磷酸激酶 (UMPK) 催化的磷酸基团从 ATP 转移到胞苷单磷酸 (CMP) 产生的。Cytidine 5′-diphosphate trisodium salt 可用于生产胞苷三磷酸 (CTP) 以合成 DNA 和 RNA。

Cytidine 5

Cytidine 5′-diphosphate trisodium salt Chemical Structure

CAS No. : 34393-59-4

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生物活性

Cytidine 5′-diphosphate trisodium salt (CDP) is produced by the transfer of phosphoryl group from ATP to cytidine monophosphate (CMP) catalyzed by uridine monophosphate kinase (UMPK). Cytidine 5′-diphosphate can be used to produce Cytidine triphosphate (CTP) for synthesis of DNA and RNA[1][2].

体内研究
(In Vivo)

CDP-ribitol can be used for the Diagnostics and research of CDP-l-ribitol pyrophosphorylase A (CRPPA) muscular dystrophy[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial

分子量

469.12

Formula

C9H12N3Na3O11P2

CAS 号

34393-59-4

中文名称

胞苷-5′-二磷酸三钠盐;胞苷5′-二磷酸三钠盐水合物;胞苷-5-二磷酸三钠盐

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

-20deg;C, protect from light, stored under nitrogen

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (protect from light, stored under nitrogen)

溶解性数据
In Vitro:;

H2O : 250 mg/mL (532.91 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.1317 mL 10.6583 mL 21.3165 mL
5 mM 0.4263 mL 2.1317 mL 4.2633 mL
10 mM 0.2132 mL 1.0658 mL 2.1317 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

参考文献
  • [1]. Moffatt BA, et, al. Purine and pyrimidine nucleotide synthesis and metabolism. Arabidopsis Book. 2002;1:e0018.

    [2]. Salvador-Silva M, et, al. Microglial cells in the retina of Carassius auratus: effects of optic nerve crush. J Comp Neurol. 2000 Feb 21;417(4):431-47.

    [3]. Tol W, et, al. Cytidine Diphosphate-Ribitol Analysis for Diagnostics and Treatment Monitoring of Cytidine Diphosphate-l-Ribitol Pyrophosphorylase A Muscular Dystrophy. Clin Chem. 2019 Oct;65(10):1295-1306.