ROS tracer precursor

生化分析试剂 Biochemical Assay Reagents
ROS tracer precursor;

ROS tracer precursor 是 [18F] ROStrace 的前体,用于合成 ROStrace,可用于疾病诊断。

ROS tracer precursor

ROS tracer precursor Chemical Structure

CAS No. : 2153480-20-5

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

ROS tracer precursor is the precursor of [18F]ROStrace for the synthesis of ROStrace, which can be used for disease diagnosis[1].

体内研究
(In Vivo)

[18F]ROStrace is a radiotracer for imaging superoxide in vivo with positron emission tomography (PET), in an LPS model of neuroinflammation. [18F]ROStrace is found to rapidly cross the blood-brain barrier (BBB) and is trapped in the brain of LPS-treated animals. [18F]ox-ROStrace, the oxidized form of [18F]ROStrace, does not cross the BBB. [18F]ROStrace is a suitable radiotracer for imaging superoxide levels in the central nervous system with PET[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

715.85

Formula

C39H45N3O8S

CAS 号

2153480-20-5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Hou C, et al. Development of a Positron Emission Tomography Radiotracer for Imaging Elevated Levels of Superoxide in Neuroinflammation. ACS Chem Neurosci. 2018 Mar 21;9(3):578-586.