Soyasaponin II 是具有抗病毒活性的皂苷。Soyasaponin II 抑制 HSV-1,HCMV,流感病毒和 HIV-1 的复制。Soyasaponin II 对 HSV-1 复制显示出有效的抑制作用。Soyasaponin II 作为 YB-1 磷酸化和 NLRP3 炎性小体引发的抑制剂,可保护小鼠免受 LPS/GalN 诱导的急性肝衰竭。
Soyasaponin II Chemical Structure
CAS No. : 55319-36-3
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价格
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数量
1 mg
¥1500
In-stock
5 mg
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生物活性
Soyasaponin II is a saponin with antiviral activity. Soyasaponin II inhibits the replication of HSV-1, HCMV, influenza virus, and HIV-1. Soyasaponin II shows potent inhibition on HSV-1 replication. Soyasaponin II serves as a inhibitor for YB-1 phosphorylation and NLRP3 inflammasome priming and could protect mice against LPS/GalN induced acute liver failure[1][2].
IC50 & Target[1][2]
HSV-1
54 μM (IC50)
HIV-1
112 μM (IC50)
influenza virus
88 μM (IC50)
HCMV
104 μM (IC50)
NLRP3 inflammasome
体外研究 (In Vitro)
Soyasaponin II inhibits the replication of HSV-1 (IC50=54μM), HCMV (104μM), influenza virus (88μM), and HIV-1 (112 μM)[1].
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究 (In Vivo)
Soyasaponin II (5 mg/kg; p.o.; once a day for three consecutive days) ameliorates canonical NLRP3 inflammasome-associated innate immune response[2].
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量
913.10
Formula
C47H76O17
CAS 号
55319-36-3
运输条件
Room temperature in continental US; may vary elsewhere.
[1]. Hayashi K, et al. Inhibitory activity of soyasaponin II on virus replication in vitro. Planta Med. 1997;63(2):102-105.
[2]. Wang F, et al. Soyasaponin II protects against acute liver failure through diminishing YB-1 phosphorylation and Nlrp3-inflammasome priming in mice. Theranostics. 2020;10(6):2714-2726. Published 2020 Feb 3.
Soyasaponin III 是一类单链齐墩果烷三萜类化合物,是大豆 (Glycine max) 及其相关产品中发现的主要潜在生物活性皂苷之一。Soyasaponin III 可以诱导 Hep-G2 细胞凋亡。
Soyasaponin III Chemical Structure
CAS No. : 55304-02-4
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是否有货
数量
1 mg
¥4800
In-stock
5 mg
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10 mg
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Soyasaponin III 相关产品
bull;相关化合物库:
Natural Product Library Plus
Bioactive Compound Library Plus
生物活性
Soyasaponin III, a monodesmodic oleanane triterpenoid, is one of the main potentially bioactive saponins found in soy (Glycine max) and related products. Soyasaponin III can induce apoptosis in Hep-G2 cells[1].
分子量
796.98
Formula
C42H68O14
CAS 号
55304-02-4
中文名称
大豆皂苷 III
运输条件
Room temperature in continental US; may vary elsewhere.
[1]. Zhang W, et al. Group B oleanane triterpenoid extract containing soyasaponins I and III from soy flour inducesapoptosis in Hep-G2 cells. J Agric Food Chem. 2010 May 12;58(9):5315-9.
Soyasaponin Ab 是一种大豆皂苷,在 3T3-L1 脂肪细胞中通过下调 PPARγ 产生抗肥胖作用。
Soyasaponin Ab Chemical Structure
CAS No. : 118194-13-1
规格
价格
是否有货
数量
5 mg
¥2020
In-stock
10 mg
¥3430
In-stock
50 mg
;
询价
;
100 mg
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Soyasaponin Ab 相关产品
bull;相关化合物库:
Natural Product Library Plus
Bioactive Compound Library Plus
Natural Product Library
Glycoside Compound Library
Medicine Food Homology Compound Library
Traditional Chinese Medicine Monomer Library
Anti-Obesity Compound Library
Food-Sourced Compound Library
生物活性
Soyasaponin Ab is a soyasaponin that exerts an anti-obesity effect in 3T3-L1 adipocytes through downregulation of peroxisome proliferator-activated receptor γ (PPARγ)[1].
分子量
1437.52
Formula
C67H104O33
CAS 号
118194-13-1
中文名称
大豆皂苷Ab
运输条件
Room temperature in continental US; may vary elsewhere.
[1]. Yang SH, et al. Soyasaponins Aa and Ab exert an anti-obesity effect in 3T3-L1 adipocytes through downregulation of PPARγ. Phytother Res. 2015 Feb;29(2):281-7.
Soyasaponin IV, isolated from the aerial parts of Glycine soya, exhibits a hepatoprotective action[1].
分子量
766.95
Formula
C41H66O13
CAS 号
108906-97-4
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Powder
-20deg;C
3 years
In solvent
-80deg;C
6 months
-20deg;C
1 month
参考文献
[1]. J Kinjo, et al. Structure-hepatoprotective relationships study of soyasaponins I-IV having soyasapogenol B as aglycone. Planta Med. 1998 Apr;64(3):233-6.
Soyasaponin Aa 是一种大豆皂苷,在 3T3-L1 脂肪细胞中通过下调 PPARγ 产生抗肥胖作用。
Soyasaponin Aa Chemical Structure
CAS No. : 117230-33-8
规格
价格
是否有货
5 mg
¥9000
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生物活性
Soyasaponin Aa is a soyasaponin that exerts an anti-obesity effect in 3T3-L1 adipocytes through downregulation of peroxisome proliferator-activated receptor γ (PPARγ)[1].
分子量
1365.46
Formula
C64H100O31
CAS 号
117230-33-8
中文名称
大豆皂苷Aa
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献
[1]. Yang SH, et al. Soyasaponins Aa and Ab exert an anti-obesity effect in 3T3-L1 adipocytes through downregulation of PPARγ. Phytother Res. 2015 Feb;29(2):281-7.