标签归档：somatostatin

Pro-Somatostatin (1-32) / N-Terminal Prepro-Somatostatin (Porcine) 品牌：Anygen

发表于由

Pro-Somatostatin (1-32) / N-Terminal Prepro-Somatostatin (Porcine)

品牌：Anygen
CAS No.：
储存条件：-20℃
纯度：–
产品编号

(生产商编号)

 等级 规格 运输包装 零售价(RMB) 库存情况 参考值

302-37163

 – 0.5 mg – 咨询 – –


* 干冰运输、大包装及大批量的产品需酌情添加运输费用


* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动，恕不另行通知，确切详情请联系上海金畔生物科技有限公司。

Somatostatin Analog RC-160 品牌：Anygen

发表于由

Somatostatin Analog RC-160

品牌：Anygen
CAS No.：
储存条件：-20℃
纯度：–
产品编号

(生产商编号)

 等级 规格 运输包装 零售价(RMB) 库存情况 参考值

305-91351

 – 0.5 mg – 咨询 – –


* 干冰运输、大包装及大批量的产品需酌情添加运输费用


* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动，恕不另行通知，确切详情请联系上海金畔生物科技有限公司。

[Tyr1]-Somatostatin-14

发表于由

[Tyr1]-Somatostatin-14;

[Tyr1]-Somatostatin-14 可结合到生长激素抑制素受体 SSTR2。

[Tyr1]-Somatostatin-14amp;;

[Tyr1]-Somatostatin-14 Chemical Structure

CAS No. : 59481-23-1

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

[Tyr1]-Somatostatin-14 could binds to SSTR2[1].

分子量

1730.00

Formula

C82H108N18O20S2
CAS 号

59481-23-1
Sequence Shortening

YGCKNFFWKTFTSC (Disulfide bridge: Cys3-Cys14)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. S Kagimoto, et al. Human somatostatin receptor, SSTR2, is coupled to adenylyl cyclase in the presence of Gi alpha 1 protein. Biochem Biophys Res Commun. 1994 Jul 29;202(2):1188-95.

[Tyr11]-Somatostatin

发表于由

[Tyr11]-Somatostatin;

[Tyr11]-Somatostatin 是一种用于蛋白质组学研究的神经活性肽。Somatostatin 是影响视网膜生理的多种神经活性物质之一。

[Tyr11]-Somatostatinamp;;

[Tyr11]-Somatostatin Chemical Structure

CAS No. : 59481-27-5

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

[Tyr11]-Somatostatin is a neuroavtive peptide for proteomics research. Somatostatin is one of many neuroactive substances that influence retinal physiology[1].

体外研究
(In Vitro)

Iodination of [Tyr11]-Somatostatin yields a super high affinity ligand for somatostatin receptors in GH4C1 pituitary cells[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

1653.88

Formula

C76H104N18O20S2
CAS 号

59481-27-5
Sequence

Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Tyr-Thr-Ser-Cys (Disulfide bridge:Cys3-Cys14)
Sequence Shortening

AGCKNFFWKTYTSC (Disulfide bridge:Cys3-Cys14)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Vasilaki A, et al. Somatostatin mediates nitric oxide production by activating sst(2) receptors in the rat retina. Neuropharmacology. 2002;43(5):899-909.

    [2]. Presky DH, Schonbrunn A. Iodination of [Tyr11]somatostatin yields a super high affinity ligand for somatostatin receptors in GH4C1 pituitary cells. Mol Pharmacol. 1988;34(5):651-658.

Somatostatin-28 (1-12)(Synonyms: 1-12-Somatostatin-28)

发表于由

Somatostatin-28 (1-12);(Synonyms: 1-12-Somatostatin-28)

Somatostatin-28 (1-12) 是生长抑素片段，在脑组织中监测以追踪生长抑素的加工。

Somatostatin-28 (1-12)amp;;(Synonyms: 1-12-Somatostatin-28)

Somatostatin-28 (1-12) Chemical Structure

CAS No. : 81286-16-0

规格 价格 是否有货
1 mg ￥1400 询问价格 货期
5 mg ￥5600 询问价格 货期
10 mg ￥9500 询问价格 货期

* Please select Quantity before adding items.

生物活性

Somatostatin-28 (1-12) is a somatostatin fragment that is monitored in brain tissue to track processing of somatostatin.

分子量

1244.33

Formula

C49H81N17O19S
CAS 号

81286-16-0
Sequence

Ser-Ala-Asn-Ser-Asn-Pro-Ala-Met-Ala-Pro-Arg-Glu
Sequence Shortening

SANSNPAMAPRE
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.

Somatostatin-25

发表于由

Somatostatin-25;

Somatostatin-25 是一种内源性神经肽激素，能够抑制生长激素的分泌。

Somatostatin-25amp;;

Somatostatin-25 Chemical Structure

CAS No. : 76461-17-1

规格 价格 是否有货
500 μg ￥2200 询问价格 货期
1 mg ￥3500 询问价格 货期
5 mg ￥9900 询问价格 货期

* Please select Quantity before adding items.

生物活性

Somatostatin-25 is a endogenous neuropeptide hormone that shows inhibitory activity against secretion of growth hormone.

体外研究
(In Vitro)

Somatostatin-25 (0.1 pM-1 nM) significantly inhibits secretion of growth hormone in the in vitro system, and is 3-14 times more effective than the tetradecapeptide. Somatostatin-25 (0.1 nM-1pM) also inhibits secretion of growth hormone induced by the addition of prostaglandin 2 (PGE2). However, Somatostatin-25 shows no effect on the secretion of prolactin[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

2876.30

Formula

C127H191N37O34S3
CAS 号

76461-17-1
Sequence

Ser-Asn-Pro-Ala-Met-Ala-Pro-Arg-Glu-Arg-Lys-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys (Disulfide bridge: Cys14-Cys25)
Sequence Shortening

SNPAMAPRERKAGCKNFFWKTFTSC (Disulfide bridge: Cys14-Cys25)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. Brazeau P, et al. High biological activity of the synthetic replicates of somatostatin-28 and somatostatin-25. Regul Pept. 1981 Jan;1(4):255-64.

Somatostatin-28 (1-14)

发表于由

Somatostatin-28 (1-14);

Somatostatin-28 (1-14) 是神经肽生长抑素-28的N-末端片段。

Somatostatin-28 (1-14)amp;;

Somatostatin-28 (1-14) Chemical Structure

CAS No. : 79243-10-0

规格 价格 是否有货
1 mg ￥1800 询问价格 货期
5 mg ￥7200 询问价格 货期
10 mg ￥11000 询问价格 货期

* Please select Quantity before adding items.

生物活性

Somatostatin-28 (1-14) is an N-terminal fragment of the neuropeptide somatostatin-28.

体外研究
(In Vitro)

The tetradecapeptide hormone somatostatin arises from proteolytic processing of a large precursor, preprosomatostatin[1]. Somatostatin-28 (1-14) has been used to produce antibodies selective for somatostatin-28 that do not bind to the C-terminal fragment somatostatin-14[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

1528.71

Formula

C61H105N23O21S
CAS 号

79243-10-0
Sequence

Ser-Ala-Asn-Ser-Asn-Pro-Ala-Met-Ala-Pro-Arg-Glu-Arg-Lys
Sequence Shortening

SANSNPAMAPRERK
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. Goodman RH, et al. Rat pre-prosomatostatin. Structure and processing by microsomal membranes. J Biol Chem. 1983 May 10;258(9):5570-3.

    [2]. Zeggari M, et al. Co-purification of a protein tyrosine phosphatase with activated somatostatin receptors from rat pancreatic acinar membranes. Biochem J. 1994 Oct 15;303 ( Pt 2):441-8.

Cyclic somatostatin(Synonyms: 环状生长激素抑制素 SRIF-14 Somatostatin-14)

发表于由

Cyclic somatostatin;(Synonyms: 环状生长激素抑制素; SRIF-14; Somatostatin-14) 纯度: 99.77%

Cyclic somatostatin (SRIF-14) 是一种生长激素释放抑制因子，可用于胃十二指肠溃疡出血研究。

Cyclic somatostatinamp;;(Synonyms: 环状生长激素抑制素; SRIF-14; Somatostatin-14)

Cyclic somatostatin Chemical Structure

CAS No. : 38916-34-6

规格 价格 是否有货 数量
1 mg ￥450 In-stock
5 mg ￥650 In-stock
10 mg ￥750 In-stock
25 mg ￥900 In-stock
50 mg ￥1200 In-stock
100 mg ; 询价 ;
200 mg ; 询价 ;

* Please select Quantity before adding items.

Cyclic somatostatin 相关产品

bull;相关化合物库:

  • Drug Repurposing Compound Library Plus
  • FDA-Approved Drug Library Plus
  • FDA-Approved Drug Library Mini
  • Bioactive Compound Library Plus
  • Peptide Library

生物活性

Cyclic somatostatin is a growth hormone-release inhibiting factor used in the treatment of severe, acute hemorrhages of gastroduodenal ulcers.

分子量

1637.88

Formula

C76H104N18O19S2
CAS 号

38916-34-6
Sequence Shortening

HAGCKNFFWKTFTSC-OH (Disulfide bridge: Cys3-Cys14)
中文名称

环状生长激素抑制素
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Protect from light

Powder -80deg;C 2 years
-20deg;C 1 year

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (protect from light)
溶解性数据
In Vitro:;

DMF : 100 mg/mL (61.05 mM; Need ultrasonic)

H2O : 71.3 mg/mL (43.53 mM; Need ultrasonic and warming)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 0.6105 mL 3.0527 mL 6.1055 mL
5 mM 0.1221 mL 0.6105 mL 1.2211 mL
10 mM 0.0611 mL 0.3053 mL 0.6105 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

Somatostatin(Synonyms: 生长激素抑制素)

发表于由

Somatostatin;(Synonyms: 生长激素抑制素)

Somatostatin 是一种可抑制生长激素 (GH) 分泌的十四肽，也可以控制人中枢神经系统中垂体激素的分泌。

Somatostatinamp;;(Synonyms: 生长激素抑制素)

Somatostatin Chemical Structure

CAS No. : 51110-01-1

规格 价格 是否有货 数量
1 mg ￥900 In-stock
5 mg ￥3600 询价
10 mg ; 询价 ;
50 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

Somatostatin is a tetradecapeptide which can suppress the growth hormone (GH) secretion and control the pituitary hormone secretion in human CNS.

体外研究
(In Vitro)

Somatostatin is a tetradecapeptide which can suppress the growth hormone (GH) secretion and control the pituitary hormone secretion in human CNS. Somatostatin has two biologically active forms: the predominant form is the 14 amino-acid long Somatostatin-14 while the more potent form is the amino-terminus extended Somatostatin-28. The biological roles of the two Somatostatin isoforms very strongly overlap and the relative proportions of Somatostatin-14 to Somatostatin-28 vary between different tissues. Somatostatin can reduce adhesion of carcinosarcoma cells to the blood vessels and thus attenuate the metastatic potential of these tumours. Somatostatin can also inhibit monocyte chemotactic migration[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial

分子量

1637.88

CAS 号

51110-01-1
Sequence

H-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH (Disulfide bridge: Cys3-Cys14)
Sequence Shortening

HAGCKNFFWKTFTSC-OH (Disulfide bridge: Cys3-Cys14)
中文名称

生长激素抑制素
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -80deg;C 2 years
-20deg;C 1 year
In solvent -80deg;C 6 months
-20deg;C 1 month
溶解性数据
In Vitro:;

H2O : 50 mg/mL (30.53 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 0.6105 mL 3.0527 mL 6.1055 mL
5 mM 0.1221 mL 0.6105 mL 1.2211 mL
10 mM 0.0611 mL 0.3053 mL 0.6105 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Msaouel P, et al. Somatostatin and somatostatin receptors: implications for neoplastic growth and cancer biology. Expert Opin Investig Drugs. 2009 Sep;18(9):1297-316.

(Tyr1)-Somatostatin 品牌：Peptide

发表于由

(Tyr1)-Somatostatin

品牌：Peptide
CAS No.：
储存条件：-20℃
纯度：–
产品编号

(生产商编号)

 等级 规格 运输包装 零售价(RMB) 库存情况 参考值

333-40381

 – 0.5mg – 咨询 – –


* 干冰运输、大包装及大批量的产品需酌情添加运输费用


* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动，恕不另行通知，确切详情请联系上海金畔生物科技有限公司。