Cyclo(RGDyK)

Cyclo(RGDyK);

Cyclo(RGDyK) 是一种有效的选择性 αVβ3 整联蛋白 (integrin) 抑制剂,IC50 为 20 nM。

Cyclo(RGDyK)amp;;

Cyclo(RGDyK) Chemical Structure

CAS No. : 217099-14-4

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Cyclo(RGDyK) 的其他形式现货产品:

Cyclo(RGDyK) trifluoroacetate

生物活性

Cyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with an IC50 of 20 nM.

IC50 Target

IC50: 20 nM (αVβ3 Integrin), 3000 nM (αIIbβ3 Integrin), 4000 nM (αVβ5 Integrin)[1]

体外研究
(In Vitro)

Cyclo(RGDyK) (c(RGDyK(SAA)) shows high affinity and selectivity for αVβ3 over αVβ5 (IC50=4000 nM) and αIIbβ3 (IC50=3000 nM)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

619.67

Formula

C27H41N9O8

CAS 号

217099-14-4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Haubner R, et al. Glycosylated RGD-containing peptides: tracer for tumor targeting and angiogenesis imaging with improved biokinetics. J Nucl Med. 2001 Feb;42(2):326-36.