标签归档：resorufin

Resorufin sodium salt(Synonyms: 试卤灵钠盐 NSC 12097 sodium salt)

发表于由

Resorufin sodium salt;(Synonyms: 试卤灵钠盐; NSC 12097 sodium salt) 纯度: 96.04%

Resorufin sodium salt (NSC 12097 sodium salt) 是一种高荧光的粉红色染料，用于检测 ROS/RNS 和第二种分析物。

Resorufin sodium saltamp;;(Synonyms: 试卤灵钠盐; NSC 12097 sodium salt)

Resorufin sodium salt Chemical Structure

CAS No. : 34994-50-8

规格 价格 是否有货 数量
10;mM;*;1 mL in DMSO ￥880 In-stock
100 mg ￥800 In-stock
200 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

Resorufin sodium salt 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus

生物活性

Resorufin sodium salt (NSC 12097 sodium salt) is a highly fluorescent pink dye for the detection of ROS/RNS and a second analyte[1].

分子量

235.17

Formula

C12H6NNaO3
CAS 号

34994-50-8
中文名称

试卤灵钠盐
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4deg;C, sealed storage, away from moisture

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture)
溶解性数据
In Vitro:;

H2O : 100 mg/mL (425.22 mM; Need ultrasonic)

DMSO : 62.5 mg/mL (265.77 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 4.2522 mL 21.2612 mL 42.5224 mL
5 mM 0.8504 mL 4.2522 mL 8.5045 mL
10 mM 0.4252 mL 2.1261 mL 4.2522 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂：

——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用； 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶

  • 1.

    请依序添加每种溶剂：;10% DMSO ;; 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (8.84 mM); Clear solution

    此方案可获得 ≥ 2.08 mg/mL (8.84 mM，饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例，取 100 μL 20.8 mg/mL 的澄清 DMSO 储备液加到 900 μL 20% 的 SBE-β-CD 生理盐水水溶液中，混合均匀。

    将 2 g 磺丁基醚 β-环糊精加入 5 mL 生理盐水中，再用生理盐水定容至 10 mL，完全溶解，澄清透明
*以上所有助溶剂都可在 MCE 网站选购。
参考文献

  • [1]. Odyniec ML , et al. ‘AND’-based fluorescence scaffold for the detection of ROS/RNS and a second analyte. Chem Commun (Camb). 2018 Jul 26;54(61):8466-8469.

Resorufin(Synonyms: 试卤灵 NSC 12097)

发表于由

Resorufin;(Synonyms: 试卤灵; NSC 12097)

Resorufin (NSC 12097) 是一种高荧光的粉红色染料，用于检测 ROS/RNS 和第二种分析物。

Resorufinamp;;(Synonyms: 试卤灵; NSC 12097)

Resorufin Chemical Structure

CAS No. : 635-78-9

规格 价格 是否有货 数量
10;mM;*;1 mL in DMSO ￥880 In-stock
100 mg ￥800 In-stock
250 mg ￥1300 In-stock
500 mg ￥2100 In-stock
1 g ￥2800 In-stock
5 g ; 询价 ;
10 g ; 询价 ;

* Please select Quantity before adding items.

Resorufin 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus

生物活性

Resorufin (NSC 12097) is a highly fluorescent pink dye for the detection of ROS/RNS and a second analyte[1].

分子量

213.19

Formula

C12H7NO3
CAS 号

635-78-9
中文名称

试卤灵
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20deg;C 3 years
4deg;C 2 years
In solvent -80deg;C 6 months
-20deg;C 1 month
溶解性数据
In Vitro:;

Ethanol : < 1 mg/mL (ultrasonic) (insoluble)

DMF : < 1 mg/mL (ultrasonic) (insoluble)

DMSO : < 1 mg/mL (ultrasonic) (insoluble or slightly soluble)

H2O : < 0.1 mg/mL (ultrasonic) (insoluble)
参考文献

  • [1]. Odyniec ML , et al. ‘AND’-based fluorescence scaffold for the detection of ROS/RNS and a second analyte. Chem Commun (Camb). 2018 Jul 26;54(61):8466-8469.

7-Ethoxyresorufin(Synonyms: Resorufin ethyl ether)

发表于由

7-Ethoxyresorufin;(Synonyms: Resorufin ethyl ether) 纯度: 98.83%

7-Ethoxyresorufin (Resorufin ethyl ether) 是细胞色素 P450 (尤其是 CYP1A1) 的荧光底物和竞争性抑制剂。7-Ethoxyresorufin 也抑制 NO 合酶 (NO synthase)。

7-Ethoxyresorufinamp;;(Synonyms: Resorufin ethyl ether)

7-Ethoxyresorufin Chemical Structure

CAS No. : 5725-91-7

规格 价格 是否有货 数量
10;mM;*;1 mL in DMSO ￥770 In-stock
5 mg ￥700 In-stock
10 mg ￥1200 In-stock
25 mg ￥2500 In-stock
50 mg ￥4500 In-stock
100 mg ￥7500 询价
200 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

7-Ethoxyresorufin 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus
  • Immunology/Inflammation Compound Library
  • Metabolism/Protease Compound Library
  • Anti-Aging Compound Library
  • Antioxidants Compound Library
  • Oxygen Sensing Compound Library
  • Neuroprotective Compound Library
  • Angiogenesis Related Compound Library

生物活性

7-Ethoxyresorufin (Resorufin ethyl ether) is a fluorometric substrate and competitive inhibitor of cytochrome P450, especially CYP1A1. 7-Ethoxyresorufin also inhibits NO synthase[1][2].

分子量

241.24

Formula

C14H11NO3
CAS 号

5725-91-7
中文名称

乙氧基试卤灵；7-乙氧基-3H-吩恶嗪-3-酮
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20deg;C 3 years
In solvent -80deg;C 6 months
-20deg;C 1 month
溶解性数据
In Vitro:;

DMF : 2 mg/mL (8.29 mM; ultrasonic and warming and heat to 60°C)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 4.1452 mL 20.7262 mL 41.4525 mL
5 mM 0.8290 mL 4.1452 mL 8.2905 mL
10 mM — — —

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. C G Li, et al. Inhibition of NO-medicate responses by 7-ethoxyresorufin, a substrate and competitive inhibitor of cytochrome P450. Br J Pharmacol. 1996 May;118(1):57-62.

    [2]. Thomas K H Chang, et al. Enzymatic analysis of cDNA-expressed human CYP1A1, CYP1A2, and CYP1B1 with 7-ethoxyresorufin as substrate. Methods Mol Biol. 2006;320:85-90.

Resorufin pentyl ether(Synonyms: 7-羟基吩噁嗪酮二戊醚 Pentoxyresorufin)

发表于由

Resorufin pentyl ether;(Synonyms: 7-羟基吩噁嗪酮二戊醚; Pentoxyresorufin)

Resorufin pentyl ether (Pentoxyresorufin) 是一种 Resazurin (HY-111391) 类似物。Resorufin pentyl ether 能作为底物来区分不同诱导物对细胞色素 P-450 的诱导。Resorufin pentyl ether 对 N. gonorrhoeae 具有杀菌活性。

Resorufin pentyl etheramp;;(Synonyms: 7-羟基吩噁嗪酮二戊醚; Pentoxyresorufin)

Resorufin pentyl ether Chemical Structure

CAS No. : 87687-03-4

规格 是否有货
5 mg 询价
10 mg 询价
50 mg 询价
100 mg 询价

* Please select Quantity before adding items.

生物活性

Resorufin pentyl ether (Pentoxyresorufin) is a Resazurin (HY-111391) analogue. Resorufin pentyl ether can function as a substrate probe to characterize and differentiate between a variety of inducers of cytochromes P-450. Resorufin pentyl ether has bactericidal activity against N. gonorrhoeae[1][2].

分子量

283.32

Formula

C17H17NO3
CAS 号

87687-03-4
中文名称

7-羟基吩噁嗪酮二戊醚
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Deanna M. Schmitt, et al. Antibacterial activity of resazurin-based compounds against Neisseria gonorrhoeae in vitro and in vivo. Int J Antimicrob Agents. 2016 Oct; 48(4): 367–372.

    [2]. M D Burke, et al. Ethoxy-, pentoxy- and benzyloxyphenoxazones and homologues: a series of substrates to distinguish between different induced cytochromes P-450. Biochem Pharmacol. 1985 Sep 15;34(18):3337-45.

Resorufin methyl ether(Synonyms: Methoxyresorufin)

发表于由

Resorufin methyl ether;(Synonyms: Methoxyresorufin)

Resorufin methyl ether (Methoxyresorufin) 是一种细胞色素 P450 的荧光底物，是啮齿动物中 CYP1A2 特异性底物。

Resorufin methyl etheramp;;(Synonyms: Methoxyresorufin)

Resorufin methyl ether Chemical Structure

CAS No. : 5725-89-3

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

Resorufin methyl ether (Methoxyresorufin) is a cytochrome P450 fluorometric substrate[1]. Resorufin methyl ether is a relatively specific substrate for CYP1A2 activity in rodents[1][2].

分子量

227.22

Formula

C13H9NO3
CAS 号

5725-89-3
中文名称

甲氧基试卤灵
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. P V Nerurkar, et al. Methoxyresorufin and benzyloxyresorufin: substrates preferentially metabolized by cytochromes P4501A2 and 2B, respectively, in the rat and mouse. Biochem Pharmacol. 1993 Sep 1;46(5):933-43.

    [2]. Hansen Murcia, et al. Study on the inhibitory effect of furafylline and troleandomycin in the 7-methoxyresorufin-O-demethylase and nifedipine oxidase activities in hepatic microsomes from four poultry species using high-performance liquid chromatography coupled with fluorescence and ultraviolet detection. J Pharm Biomed Anal. 2019 Feb 5;164:148-154.