PUMA BH3 TFA

发表于2024年7月4日由Whatman官网

PUMA BH3 TFA;

PUMA BH3 (TFA) 是一种 p53 正向凋亡调控因子 (PUMA) BH3 结构域多肽，作为 Bak 的直接激活剂，K_d 值为 26 nM。

PUMA BH3 TFA Chemical Structure

规格		是否有货
100 mg	;	询价	;
250 mg	;	询价	;
500 mg	;	询价	;

* Please select Quantity before adding items.

生物活性

PUMA BH3 (TFA) is a p53 upregulated modulator of apoptosis (PUMA) BH3 domain peptide, acts as a direct activator of Bak, with a K_d of 26 nM^[1].

IC₅₀ Target^[1]

Bak

26 nM (Kd)

分子量

3163.32

Formula

C₁₃₀H₂₀₃F₃N₄₂O₄₅S

Sequence Shortening

EEQWAREIGAQLRRMADDLNAQYER

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献

[1]. Dai H, et al. Evaluation of the BH3-only protein Puma as a direct Bak activator. J Biol Chem. 2014 Jan 3;289(1):89-99.

PUMA BH3

发表于2024年7月1日由Whatman官网

PUMA BH3;

PUMA BH3 是一种 p53 正向凋亡调控因子 (PUMA) BH3结构域多肽，作为 Bak 的直接激活剂，K_d 值为 26 nM。

PUMA BH3 Chemical Structure

规格	价格	是否有货
1 mg	￥1500	询问价格货期
5 mg	￥3500	询问价格货期
10 mg	￥5500	询问价格货期

* Please select Quantity before adding items.

生物活性

PUMA BH3 is a p53 upregulated modulator of apoptosis (PUMA) BH3 domain peptide, acts as a direct activator of Bak, with a K_d of 26 nM.

IC₅₀ Target^[1]

Bak

26 nM (Kd)

体外研究
(In Vitro)

PUMA BH3 is a p53 upregulated modulator of apoptosis (PUMA) BH3 domain peptide, acts as a direct activator of Bak, with a K_d of 26 nM. PUMA BH3 binds Bak in the canonical BH3-binding groove, and activates Bak^[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

3049.30