标签归档：proinsulin

Proinsulin C-Peptide (31-63), porcine

发表于由

Proinsulin C-Peptide (31-63), porcine;

Proinsulin C-Peptide (31-63), porcine 是猪胰岛素原裂解产物的多肽片段。

Proinsulin C-Peptide (31-63), porcineamp;;

Proinsulin C-Peptide (31-63), porcine Chemical Structure

CAS No. : 28152-90-1

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

Proinsulin C-Peptide (31-63), porcine is a peptide fragment of the cleavage product porcine proinsulin[1].

分子量

3340.70

Formula

C142H239N47O46
CAS 号

28152-90-1
Sequence Shortening

RREAENPQAGAVELGGGLGGLQALALEGPPQKR
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. Chance RE, et, al. Porcine proinsulin: characterization and amino acid sequence. Science. 1968 Jul 12; 161(3837): 165-7.

Proinsulin C-Peptide (55-89), human

发表于由

Proinsulin C-Peptide (55-89), human;

Proinsulin C-Peptide (55-89), human 是人胰岛素原裂解产物的多肽片段。

Proinsulin C-Peptide (55-89), humanamp;;

Proinsulin C-Peptide (55-89), human Chemical Structure

CAS No. : 11097-48-6

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

Proinsulin C-Peptide (55-89), human is a peptide fragment of the cleavage product of proinsulin[1].

分子量

3616.99

Formula

C153H259N49O52
CAS 号

11097-48-6
Sequence

Arg-Arg-Glu-Ala-Glu-Asp-Leu-Gln-Val-Gly-Gln-Val-Glu-Leu-Gly-Gly-Gly-Pro-Gly-Ala-Gly-Ser-Leu-Gln-Pro-Leu-Ala-Leu-Glu-Gly-Ser-Leu-Gln-Lys-Arg
Sequence Shortening

RREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKR
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. Essid SM, et al. Proinsulin C-Peptide Enhances Cell Survival and Protects against Simvastatin-Induced Myotoxicity in L6 Rat Myoblasts. Int J Mol Sci. 2019 Apr 3;20(7).

Proinsulin C-peptide (human)

发表于由

Proinsulin C-peptide (human);

Proinsulin C-peptide (human) 是一种由 31 个氨基酸残基构成的多肽，连接胰岛素原 A 链和 B 链以确保其正确折叠，具有生物活性和调节细胞的功能。

Proinsulin C-peptide (human)amp;;

Proinsulin C-peptide (human) Chemical Structure

CAS No. : 33017-11-7

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

Proinsulin C-peptide (human) is a 31-amino-acid peptide that links the A and B chains of proinsulin, ensuring its correct folding, which is biologically active and modulates cellular function [1].

分子量

3020.26

Formula

C129H211N35O48
CAS 号

33017-11-7
Sequence

Glu-Ala-Glu-Asp-Leu-Gln-Val-Gly-Gln-Val-Glu-Leu-Gly-Gly-Gly-Pro-Gly-Ala-Gly-Ser-Leu-Gln-Pro-Leu-Ala-Leu-Glu-Gly-Ser-Leu-Gln
Sequence Shortening

EAEDLQVGQVELGGGPGAGSLQPLALEGSLQ
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. R. S. Mughal, et al. Cellular mechanisms by which proinsulin C-peptide prevents insulin-induced neointima formation in human saphenous vein. Diabetologia. 2010 Aug;53(8):1761-71.

Kerafast EGA415 Anti-Proinsulin [8E7.B12] Antibody, 100ug 100ug

发表于由

上海金畔生物科技有限公司提供Kerafast EGA415 Anti-Proinsulin [8E7.B12] Antibody, 100ug 100ug，欢迎访问官网了解更多产品信息和订购

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