Novokinin TFA

发表于2024年10月30日由Whatman官网

Novokinin TFA;

Novokinin TFA 是一种血管紧张素 AT2 受体的肽类激动剂。

Novokinin TFA Chemical Structure

CAS No. : 1262750-59-3

规格		是否有货
100 mg	;	询价	;
250 mg	;	询价	;
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生物活性

Novokinin TFA is a peptide agonist of the angiotensin AT2 receptor^[1].

体内研究
(In Vivo)

Novokinin TFA suppresses food intake after icv. or po. administration in mice^[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

909.99

Formula

C₄₁H₆₂F₃N₁₁O₉

CAS 号

1262750-59-3

Sequence Shortening

RPLKPW

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent Solubility

In Vitro:;

H₂O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

;	Contents	Assign value
Acidic amino acid	Asp (D), Glu (E), and the C-terminal -COOH.	-1
Basic amino acid	Arg (R), Lys (K), His (H), and the N-terminal -NH₂	+1
Neutral amino acid	Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q)	0

3.;;Recommended solution:

Overall charge of peptide	Details
Negative (lt;0)	1.;;Try to dissolve the peptide in water first. 2.;;If water fails, add NH₄OH (lt;50 μL). 3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0)	1.;;Try to dissolve the peptide in water first. 2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution. 3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0)	1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first. 2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.

参考文献

[1]. Masaaki Yoshikawa, et al. The pharmacological effects of novokinin; a designed peptide agonist of the angiotensin AT2 receptor. Curr Pharm Des. 2013;19(17):3009-12.

Novokinin

发表于2024年7月10日由Whatman官网

Novokinin;

Novokinin 是一种血管紧张素 AT2 受体的肽类激动剂。

Novokinin Chemical Structure

CAS No. : 358738-77-9

规格		是否有货
100 mg	;	询价	;
250 mg	;	询价	;
500 mg	;	询价	;