Nidurufin

天然产物醌类Quinones

Nidurufin 

Nidurufin 是一种有效的细胞周期抑制剂,具有抗肿瘤活性。Nidurufin 以浓度和时间依赖性的方式诱导 K562 细胞系G2/M过渡期的体外细胞周期阻滞,IC50=12.6μM。

Nidurufin

Nidurufin Chemical Structure

CAS No. : 28458-23-3

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生物活性

Nidurufin is a potent cell cycle inhibitor with antitumor activity.Nidurufin induces in vitro cell cycle arrest at G2/M transition in the K562 cell line in a concentration and time dependent manner(IC50=12.6 μM)[1].

分子量

384.34

Formula

C20H16O8

CAS 号

28458-23-3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Hong Ren, et al.Nidurufin as a new cell cycle inhibitor from marine-derived fungus Penicillium flavidorsum SHK1-27. Arch Pharm Res. 2011 Jun;34(6):901-5.