Malvidin Chloride 品牌:Tokiwa Phytochemical


Malvidin Chloride

品牌:Tokiwa Phytochemical
CAS No.:
储存条件:4℃
纯度:≧98% (HPLC)
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Malvidin-3-O-arabinoside chloride

天然产物 黄酮类 Flavonoids

Malvidin-3-O-arabinoside chloride 

Malvidin-3-O-arabinoside chloride 通过刺激 Ampk 介导的自噬 (autophagy),改善氨基甲酸乙酯诱导的氧化损伤。

Malvidin-3-O-arabinoside chloride

Malvidin-3-O-arabinoside chloride Chemical Structure

CAS No. : 28500-04-1

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生物活性

Malvidin-3-O-arabinoside chloride ameliorates ethyl carbamate-induced oxidative damage by stimulating AMPK-mediated autophagy[1].

体外研究
(In Vitro)

Malvidin-3-O-arabinoside chloride (M3A chloride, 50-400 μM) pretreatment remarkably upregulates LAMP-1 expression, which indicates elevated lysosomal mass. M3A also successfully restores lysosomal acidity and subsequently strengthenes lysosomal functions. M3A stimulates phosphorylation of AMP-activated protein kinase (AMPK), a master regulator of autophagy[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Autophagy Assay[1]

Cell Line: Caco-2 cell line.
Concentration: 50, 100, 200 and 400 μM.
Incubation Time: 24 h (then treated with or without 10 μM chloroquine (CQ) for another 1 h).
Result: Notably inhibited excess ROS generation.
200 μM and 400 μM M3A pretreatment significantly enhanced 14% and 16% of GSH level.
Enhanced autophagy flux.
Significantly up-regulate the LC3-II/LC3-I ratio.

分子量

498.86

Formula

C22H23ClO11

CAS 号

28500-04-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Yuting Li, et al. Malvidin-3-O-arabinoside ameliorates ethyl carbamate-induced oxidative damage by stimulating AMPK-mediated autophagy. Food Funct. 2020 Dec 1;11(12):10317-10328.

Malvidin chloride(Synonyms: Syringidin)

天然产物 黄酮类 Flavonoids

Malvidin chloride (Synonyms: Syringidin)

Malvidin (chloride) 是一种从 Oryza sativacv. Heugjinjubyeo 中分离出来的生物活性化合物。 Malvidin 通过阻止细胞周期的 G2/M 期和诱导细胞凋亡显示出细胞毒性。Malvidin可用于癌症研究。

Malvidin chloride(Synonyms: Syringidin)

Malvidin chloride Chemical Structure

CAS No. : 643-84-5

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生物活性

Malvidin (chloride) is a bioactive compound isolated from Oryza sativacv. Heugjinjubyeo. Malvidin shows cytotoxicity through the arrest of the G2/M phase of cell cycle and induction of apoptosis. Malvidin can be used for the research of cancer[1].

体外研究
(In Vitro)

Malvidin (0~80 μg/mL; 96 hours; U937 cells) shows cytotoxic activity in a dose-dependent pattern[1].
The IC50 value of Malvidin for U937 cells is 40 μg/mL. Malvidin (U937 cells) shows arrest at the G2/M phase of the cell cycle and increases sub G1 hypo-diploid population[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: U937 cells
Concentration: 0~80 μg/mL
Incubation Time: 96 hours
Result: Showed cytotoxic activity in a dose-dependent pattern.

分子量

366.75

Formula

C17H15ClO7

CAS 号

643-84-5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Jin W H, et al. Cyanidin and Malvidin fromOryza sativacv. HeugjinjubyeoMediate Cytotoxicity against Human Monocytic Leukemia Cellsby Arrest of G2/M Phase and Induction of Apoptosis. J. Agric. Food Chem. 2004, 52, 8, 2213–2217

Malvidin-3-glucoside chloride(Synonyms: Malvidin-3-O-glucoside chloride; Oenin chloride)

天然产物 糖类和糖苷 Saccharides and Glycosides

Malvidin-3-glucoside chloride;(Synonyms: Malvidin-3-O-glucoside chloride; Oenin chloride)

Malvidin-3-glucoside chloride (Malvidin-3-O-glucoside chloride),是一种主要的葡萄酒花青素,通过调节大脑突触可塑性和外周炎症,有效地促进应激反应。

Malvidin-3-glucoside chloride(Synonyms: Malvidin-3-O-glucoside chloride; Oenin chloride)

Malvidin-3-glucoside chloride Chemical Structure

CAS No. : 7228-78-6

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1 mg ¥2600 询问价格 货期
5 mg ¥7000 询问价格 货期

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生物活性

Malvidin-3-glucoside chloride (Malvidin-3-O-glucoside chloride), a major wine anthocyanin, is effective in promoting resilience against stress by modulating brain synaptic plasticity and peripheral inflammation[1].

分子量

528.89

Formula

C23H25ClO12

CAS 号

7228-78-6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Wang J, et al. Epigenetic modulation of inflammation and synaptic plasticity promotes resilience against stress in mice. Nat Commun. 2018;9(1):477. Published 2018 Feb 2.