Isolindleyin

天然产物 糖类和糖苷 Saccharides and Glycosides

Isolindleyin;

Isolindleyin 是一种丁酰苯,是酪氨酸酶抑制剂,对人酪氨酸酶的 Kd 值为 54.8 μM。Isolindleyin 具有抗炎和抗黑色素生成活性,可用于缓解疼痛的研究。

Isolindleyin

Isolindleyin Chemical Structure

CAS No. : 87075-18-1

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生物活性

Isolindleyin, a butyrophenone, is a tyrosinase inhibitor, with a Kd of 54.8 μM for human tyrosinase. Isolindleyin exhibits anti-inflammatory, analgesic and anti-melanogenic activities[1].

IC50 Target

Kd: 54.8 μM (human tyrosinase)[1]

体外研究
(In Vitro)

Isolindley (1-500 μM; 7 days) suppresses melanin synthesis in human epidermal melanocytes[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

478.45

Formula

C23H26O11

CAS 号

87075-18-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Lee JY, et, al. Isolindleyin exerts anti-melanogenic effects in human epidermal melanocytes via direct binding to tyrosinase. Biochem Biophys Res Commun. 2021 Jan 1;534:802-807.