标签归档：idr

IDR-1

发表于由

IDR-1;

IDR-1 是一种抗菌肽，对革兰氏阳性 (Gram-positive) 和革兰氏阴性细菌 (Gram-negative bacteria) 具有活性。IDR-1 通过选择性调节先天免疫来抵抗感染，而没有明显的毒性。IDR-1 具有抗炎和抗感染特性，可增强单核细胞趋化因子的水平，并减弱促炎性细胞因子的释放。

IDR-1amp;;

IDR-1 Chemical Structure

CAS No. : 940291-10-1

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生物活性

IDR-1 is an antimicrobial peptide that is active against Gram-positive and Gram-negative bacteria. IDR-1 counters infection by selective modulation of innate immunity without obvious toxicities. IDR-1 has anti-inflammatory and anti-infective properties, enhances the levels of monocyte chemokines, and attenuates pro-inflammatory cytokine release[1][2].

分子量

1391.74

Formula

C65H118N18O15
CAS 号

940291-10-1
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Monisha G Scott, et al. An Anti-Infective Peptide That Selectively Modulates the Innate Immune Response. Nat Biotechnol. 2007 Apr;25(4):465-72.

    [2]. Man Hou, et al. Antimicrobial Peptide LL-37 and IDR-1 Ameliorate MRSA Pneumonia in Vivo. Cell Physiol Biochem. 2013;32(3):614-23.