AGA-(C8R) HNG17, humanin derivative

发表于2024年8月11日由Whatman官网

AGA-(C8R) HNG17, humanin derivative;

AGA-(C8R) HNG17, Humanin derivative 是一种有效的人类蛋白 (HN) 的衍生物。AGA-(C8R) HNG17, Humanin derivative 可完全抑制老年痴呆症相关损害引起的神经元细胞死亡。

AGA-(C8R) HNG17, humanin derivative Chemical Structure

CAS No. : 875910-01-3

规格		是否有货
100 mg	;	询价	;
250 mg	;	询价	;
500 mg	;	询价	;

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AGA-(C8R) HNG17, humanin derivative 的其他形式现货产品:

AGA-(C8R) HNG17, humanin derivative TFA

生物活性

AGA-(C8R) HNG17, Humanin derivative is a potent humanin (HN) derivative. AGA-(C8R) HNG17, Humanin derivative completely suppresses neuronal cell death by Alzheimer’s disease-relevant insults^[1].

分子量

1736.02

Formula

C₇₈H₁₃₄N₂₀O₂₄

CAS 号

875910-01-3

Sequence Shortening

PAGASRLLLLTGEIDLP

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent Solubility

In Vitro:;

H₂O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

;	Contents	Assign value
Acidic amino acid	Asp (D), Glu (E), and the C-terminal -COOH.	-1
Basic amino acid	Arg (R), Lys (K), His (H), and the N-terminal -NH₂	+1
Neutral amino acid	Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q)	0

3.;;Recommended solution:

Overall charge of peptide	Details
Negative (lt;0)	1.;;Try to dissolve the peptide in water first. 2.;;If water fails, add NH₄OH (lt;50 μL). 3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0)	1.;;Try to dissolve the peptide in water first. 2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution. 3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0)	1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first. 2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.

参考文献

[1]. Chiba T, et al. Development of a femtomolar-acting humanin derivative named colivelin by attaching activity-dependent neurotrophic factor to its N terminus: characterization of colivelin-mediated neuroprotection against Alzheimer’s disease-relevant insults in vitro and in vivo. J Neurosci. 2005 Nov 2;25(44):10252-61.

AGA-(C8R) HNG17, humanin derivative TFA

发表于2023年12月30日由Whatman官网

AGA-(C8R) HNG17, humanin derivative TFA; 纯度: 95.50%

AGA-(C8R) HNG17, humanin derivative TFA 是一种有效的人类蛋白 (HN) 的衍生物。AGA-(C8R) HNG17, humanin derivative 可完全抑制老年痴呆症相关损害引起的神经元细胞死亡。

AGA-(C8R) HNG17, humanin derivative TFAamp;;

AGA-(C8R) HNG17, humanin derivative TFA Chemical Structure

规格	价格	是否有货	数量
5 mg	￥2500	In-stock
10 mg	￥4200	In-stock
50 mg	;	询价	;
100 mg	;	询价	;

* Please select Quantity before adding items.