GIP (1-30) amide, porcine

发表于2024年9月21日由Whatman官网

GIP (1-30) amide, porcine;

GIP (1-30) amide, porcine 是一种葡萄糖依赖性促胰岛素多肽 (GIP) 受体激动剂，与天然 GIP (1-42) 的亲和力一样高。GIP (1-30) amide, porcine是一种弱的胃酸分泌抑制剂，有效刺激胰岛素分泌。

GIP (1-30) amide, porcine Chemical Structure

CAS No. : 134846-93-8

规格		是否有货
100 mg	;	询价	;
250 mg	;	询价	;
500 mg	;	询价	;

* Please select Quantity before adding items.

GIP (1-30) amide, porcine 的其他形式现货产品:

GIP (1-30) amide, porcine TFA

生物活性

GIP (1-30) amide, porcine is a full glucose-dependent insulinotropic polypeptide (GIP) receptor agonist with high affinity equal to native GIP(1-42)^[1]. GIP (1-30) amide, porcine is a weak inhibitor of gastric acid secretion and potent stimulator of insulin.

分子量

3551.00

Formula

C₁₆₂H₂₄₅N₄₁O₄₇S

CAS 号

134846-93-8

Sequence

Tyr-Ala-Glu-Gly-Thr-Phe-Ile-Ser-Asp-Tyr-Ser-Ile-Ala-Met-Asp-Lys-Ile-Arg-Gln-Gln-Asp-Phe-Val-Asn-Trp-Leu-Leu-Ala-Gln-Lys-NH2

Sequence Shortening

YAEGTFISDYSIAMDKIRQQDFVNWLLAQK-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent Solubility

In Vitro:;

H₂O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

;	Contents	Assign value
Acidic amino acid	Asp (D), Glu (E), and the C-terminal -COOH.	-1
Basic amino acid	Arg (R), Lys (K), His (H), and the N-terminal -NH₂	+1
Neutral amino acid	Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q)	0

3.;;Recommended solution:

Overall charge of peptide	Details
Negative (lt;0)	1.;;Try to dissolve the peptide in water first. 2.;;If water fails, add NH₄OH (lt;50 μL). 3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0)	1.;;Try to dissolve the peptide in water first. 2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution. 3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0)	1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first. 2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.

参考文献

[1]. L S Hansen, et al. N-terminally and C-terminally truncated forms of glucose-dependent insulinotropic polypeptide are high-affinity competitive antagonists of the human GIP receptor. Br J Pharmacol. 2016 Mar;173(5):826-38.

GIP (1-30) amide,human

发表于2024年9月8日由Whatman官网

GIP (1-30) amide,human;

GIP (1-30) amide,human 是葡萄糖依赖性促胰岛素多肽 (GIP) 片段。葡萄糖依赖性促胰岛素多肽是一种肠降血糖素激素，可刺激胰岛素分泌并减少餐后血糖波动。GIP (1-30) amide,human 在 10^-9-10^-6 M 范围内剂量依赖性地促进胰岛素分泌。

GIP (1-30) amide,human Chemical Structure

CAS No. : 198624-01-0

规格		是否有货
100 mg	;	询价	;
250 mg	;	询价	;
500 mg	;	询价	;

* Please select Quantity before adding items.

GIP (1-30) amide,human 的其他形式现货产品:

GIP (1-30) amide,human acetate

生物活性	GIP (1-30) amide,human is a glucose-dependent insulinotropic polypeptide (GIP) fragment. GIP is an incretin hormone that stimulates insulin secretion and reduces postprandial glycaemic excursions. GIP (1-30) amide,human dose-dependently promotes insulin secretion over the range 10^-9-10^-6 M^[1].
体外研究 (In Vitro)	The glucose-dependent action of Glucose-dependent insulinotropic polypeptide (GIP) on pancreatic β-cells has attracted attention towards its exploitation as a potential drug for type 2 diabetes. In a 50% aqueous trifluoroethanol solvent, GIP(1-30) amide has an α-helical structural region from F6 to A28. The structures calculated for GIP(1-30) amide remain within one family of conformations and the level of agreement between the structures demonstrated the ordered arrangement^[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量	3531.94
Formula	C₁₆₂H₂₄₀N₄₀O₄₇S
CAS 号	198624-01-0
Sequence	Tyr-Ala-Glu-Gly-Thr-Phe-Ile-Ser-Asp-Tyr-Ser-Ile-Ala-Met-Asp-Lys-Ile-His-Gln-Gln-NH2
Sequence Shortening	YAEGTFISDYSIAMDKIHQQDFVNWLLAQK-NH2
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Alaña I, et al. NMR structure of the glucose-dependent insulinotropic polypeptide fragment, GIP(1-30)amide. Biochem Biophys Res Commun. 2004 Dec 3;325(1):281-6.

GIP (1-30) amide,human acetate

发表于2024年4月26日由Whatman官网

GIP (1-30) amide,human acetate; 纯度: 98.26%

GIP (1-30) amide,human acetate 是葡萄糖依赖性促胰岛素多肽 (GIP) 片段。葡萄糖依赖性促胰岛素多肽是一种肠降血糖素激素，可刺激胰岛素分泌并减少餐后血糖波动。GIP (1-30) amide,human acetate 在 10^-9-10^-6 M 范围内剂量依赖性地促进胰岛素分泌。

GIP (1-30) amide,human acetate Chemical Structure

规格	价格	是否有货	数量
1 mg	￥1500	In-stock
5 mg	￥4500	In-stock
10 mg	￥7500	In-stock
50 mg	;	询价	;
100 mg	;	询价	;

* Please select Quantity before adding items.

GIP (1-30) amide,human acetate 相关产品

bull;相关化合物库:

Bioactive Compound Library Plus
Peptide Library

生物活性

GIP (1-30) amide,human acetate is a glucose-dependent insulinotropic polypeptide (GIP) fragment. GIP is an incretin hormone that stimulates insulin secretion and reduces postprandial glycaemic excursions. GIP (1-30) amide,human acetate dose-dependently promotes insulin secretion over the range 10^-9-10^-6 M^[1].

体外研究
(In Vitro)

The glucose-dependent action of Glucose-dependent insulinotropic polypeptide (GIP) on pancreatic β-cells has attracted attention towards its exploitation as a potential drug for type 2 diabetes. In a 50% aqueous trifluoroethanol solvent, GIP(1-30) amide has an α-helical structural region from F6 to A28. The structures calculated for GIP(1-30) amide remain within one family of conformations and the level of agreement between the structures demonstrated the ordered arrangement^[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

3591.99

Formula

C₁₆₄H₂₄₄N₄₀O₄₉S

Sequence

Tyr-Ala-Glu-Gly-Thr-Phe-Ile-Ser-Asp-Tyr-Ser-Ile-Ala-Met-Asp-Lys-Ile-His-Gln-Gln-NH2

Sequence Shortening

YAEGTFISDYSIAMDKIHQQDFVNWLLAQK-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisture

Powder	-80deg;C	2 years
	-20deg;C	1 year

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture)

溶解性数据

In Vitro:;

DMSO : 50 mg/mL (13.92 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	0.2784 mL	1.3920 mL	2.7840 mL
5 mM	0.0557 mL	0.2784 mL	0.5568 mL
10 mM	0.0278 mL	0.1392 mL	0.2784 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

参考文献

[1]. Alaña I, et al. NMR structure of the glucose-dependent insulinotropic polypeptide fragment, GIP(1-30)amide. Biochem Biophys Res Commun. 2004 Dec 3;325(1):281-6.

GIP, human TFA(Synonyms: 抑胃肽三氟乙酸盐 (人) Gastric Inhibitory Peptide (GIP), human TFA)

发表于2024年4月7日由Whatman官网

GIP, human TFA (Synonyms: 抑胃肽三氟乙酸盐 (人); Gastric Inhibitory Peptide (GIP), human TFA) 纯度: 96.24%

GIP, human TFA 是一种由 42 个氨基酸组成的肽类激素，是葡萄糖依赖性胰岛素分泌的促进剂和胃酸分泌的弱抑制剂。GIP, human TFA 作为肠 K 细胞释放的肠促胰岛素激素，对营养摄入作出反应。

GIP, human TFA Chemical Structure

规格	价格	是否有货
1 mg	￥5000	In-stock
5 mg		询价
10 mg		询价

* Please select Quantity before adding items.

GIP, human TFA 相关产品

•相关化合物库:

Bioactive Compound Library Plus
Peptide Library

生物活性

GIP, human TFA, a peptide hormone consisting of 42 amino acids, is a stimulator of glucose-dependent insulin secretion and a weak inhibitor of gastric acid secretion. GIP, human TFA acts as an incretin hormone released from intestinal K cells in response to nutrient ingestion^[1]^[2]^[3].

体外研究
(In Vitro)

Gastric Inhibitory Polypeptide (GIP) exerts various peripheral effects on adipose tissue and lipid metabolism, thereby leading to increased lipid deposition in the postprandial state^[1]. GIP, human plays a vital role in lipid metabolism and the development of obesity.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

5097.62

Formula

C₂₂₈H₃₃₉F₃N₆₀O₆₈S

Sequence

Tyr-Ala-Glu-Gly-Thr-Phe-Ile-Ser-Asp-Tyr-Ser-Ile-Ala-Met-Asp-Lys-Ile-His-Gln-Gln-Asp-Phe-Val-Asn-Trp-Leu-Leu-Ala-Gln-Lys-Gly-Lys-Lys-Asn-Asp-Trp-Lys-His-Asn-Ile-Thr-Gln

Sequence Shortening

YAEGTFISDYSIAMDKIHQQDFVNWLLAQKGKKNDWKHNITQ

中文名称

抑胃肽三氟乙酸盐 (人)

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Protect from light, stored under nitrogen

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility

In Vitro:

H₂O

Peptide Solubility and Storage Guidelines:

1. Calculate the length of the peptide.

2. Calculate the overall charge of the entire peptide according to the following table:

	Contents	Assign value
Acidic amino acid	Asp (D), Glu (E), and the C-terminal -COOH.	-1
Basic amino acid	Arg (R), Lys (K), His (H), and the N-terminal -NH₂	+1
Neutral amino acid	Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q)	0

3. Recommended solution:

Overall charge of peptide	Details
Negative (<0)	1. Try to dissolve the peptide in water first. 2. If water fails, add NH₄OH (<50 μL). 3. If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0)	1. Try to dissolve the peptide in water first. 2. If water fails, try dissolving the peptide in a 10%-30% acetic acid solution. 3. If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0)	1. Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first. 2. For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.

参考文献

[1]. Meier JJ, et al. Gastric inhibitory polypeptide: the neglected incretin revisited. Regul Pept. 2002 Jul 15;107(1-3):1-13.

[2]. Miyachi A, et al. Quantitative analytical method for determining the levels of gastric inhibitory polypeptides GIP1-42 and GIP3-42 in human plasma using LC-MS/MS/MS. J Proteome Res. 2013;12(6):2690-2699.

[3]. Gabe MBN, et al. Molecular interactions of full-length and truncated GIP peptides with the GIP receptor – A comprehensive review. Peptides. 2020;125:170224.

[1]. Meier JJ, et al. Gastric inhibitory polypeptide: the neglected incretin revisited. Regul Pept. 2002 Jul 15;107(1-3):1-13.

[2]. Miyachi A, et al. Quantitative analytical method for determining the levels of gastric inhibitory polypeptides GIP1-42 and GIP3-42 in human plasma using LC-MS/MS/MS. J Proteome Res. 2013;12(6):2690-2699.

[3]. Gabe MBN, et al. Molecular interactions of full-length and truncated GIP peptides with the GIP receptor – A comprehensive review. Peptides. 2020;125:170224.

活性肠促胰岛素GIP 特异性检测试剂盒 Mouse GIP(Active) ELISA Kit Wako

发表于2024年3月21日由Whatman官网

活性肠促胰岛素GIP 特异性检测试剂盒
Mouse GIP(Active) ELISA Kit Wako

产品特性
相关资料
Q&A
参考文献

活性肠促胰岛素GIP 特异性检测试剂盒 活性肠促胰岛素GIP 特异性检测试剂盒 Mouse GIP(Active) ELISA Kit Wako

Mouse GIP(Active) ELISA Kit Wako

和光具有定量检测糖尿病和肥胖相关因子的ELISA Kit Wako系列和测定实验动物血液中各种生化分子的LabAssay™系列，均仅需微量样品即可特异性定量各种生化指标。

◆原理

活性肠促胰岛素GIP 特异性检测试剂盒 Mouse GIP(Active) ELISA Kit Wako

GIP 是摄取糖、脂肪后由十二指肠K 细胞分泌的肠肽激素，促进胰腺β 细胞分泌肠促胰岛素1）。正常人进食后血浆中的GIP浓度会上升，但胰岛素依赖性糖尿病患者的GIP 浓度上升会被抑制。GIP 有活性型GIP（1-42）和非活性型GIP（3-42）两种亚型，GIP（1-42）会被血液中的DPP-4 分解而失活，代谢成GIP（3-42）1）。本产品是不与小鼠GIP（3-42）反应，可定量检测小鼠GIP（1-42）的ELISA 试剂盒。

本产品是特异性测定小鼠血浆中的活性型GIP浓度的ELISA试剂盒。

◆优点、特色

● 高特异性

● 实验样品为小鼠的血浆

● 测定时间短

● 高灵敏度

◆性能

● 检测范围：7.8~500 pg/mL

● 仅需样品量：25 μL

● 检测时间：3.5 小时

● 同时重复性（CV）：<7%

● 不同天检测重现性（CV）：<5%

◆检量线示例

Kit 组成

1) Antibody Coated Plate・・・・ 1 plate

2) Mouse GIP Standard・・・・・ 1,000 pg

3) HRP Labeled Antibody Solution・ 12 mL

4) Enzyme Substrate Solution ・・・ 12 mL

5) Stopping Solution・・・・・・・ 12 mL

6) Buffer Solution ・・・・・・・・ 25 mL

7) Washing Solution(concentrated)・50 mL

8) Adhesive Foil ・・・・・・・・・ 3 sheets

[1] Asmar M., Dan Med Bull. 58, 2, B4248 (2011).

产品列表

产品编号	产品名称	产品规格	产品等级	备注
299-73801	Mouse GIP(Active) ELISA Kit Wako 小鼠活性GIP检测ELISA试剂盒	96 tests	f糖尿病研究	–
291-59201	Rat GLP-1 ELISA Kit Wako	96次	糖尿病研究
295-57401	Rat C-Peptide ELISA Kit Wako	96次	糖尿病研究
297-57101	Rat Glucagon ELISA Kit Wako	96次	糖尿病研究
044-31291	DPP Ⅳ Inhibitor 1c Hydrochloride	5 mg	糖尿病研究
298-65701	LabAssay ™ Glucos	1000次	糖尿病研究

GIP (1-30) amide, porcine TFA

发表于2024年3月7日由Whatman官网

GIP (1-30) amide, porcine TFA; 纯度: 98.55%

GIP (1-30) amide, porcine TFA 是一种葡萄糖依赖性促胰岛素多肽 (GIP) 受体激动剂，与天然 GIP (1-42) 的亲和力一样高。GIP (1-30) amide, porcine是一种弱的胃酸分泌抑制剂，有效刺激胰岛素分泌。

GIP (1-30) amide, porcine TFA Chemical Structure

规格	价格	是否有货	数量
5 mg	￥3000	In-stock
10 mg	￥5000	In-stock
50 mg	;	询价	;
100 mg	;	询价	;

* Please select Quantity before adding items.

GIP (1-30) amide, porcine TFA 相关产品

bull;相关化合物库:

Bioactive Compound Library Plus
Peptide Library

生物活性

GIP (1-30) amide, porcine TFA is a full glucose-dependent insulinotropic polypeptide (GIP) receptor agonist with high affinity equal to native GIP(1-42)^[1]. GIP (1-30) amide, porcine is a weak inhibitor of gastric acid secretion and potent stimulator of insulin.

分子量

3665.02

Formula

C₁₆₄H₂₄₆F₃N₄₁O₄₉S

Sequence

Tyr-Ala-Glu-Gly-Thr-Phe-Ile-Ser-Asp-Tyr-Ser-Ile-Ala-Met-Asp-Lys-Ile-Arg-Gln-Gln-Asp-Phe-Val-Asn-Trp-Leu-Leu-Ala-Gln-Lys-NH2

Sequence Shortening

YAEGTFISDYSIAMDKIRQQDFVNWLLAQK-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisture and light

Powder	-80deg;C	2 years
	-20deg;C	1 year

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture and light)

溶解性数据

In Vitro:;

DMSO : 100 mg/mL (27.28 mM; Need ultrasonic)

H₂O : < 0.1 mg/mL (ultrasonic) (insoluble)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	0.2728 mL	1.3642 mL	2.7285 mL
5 mM	0.0546 mL	0.2728 mL	0.5457 mL
10 mM	0.0273 mL	0.1364 mL	0.2728 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂：

——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用；以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶

1.

请依序添加每种溶剂：;10% DMSO ;; 90% (20% SBE-β-CD in saline)

Solubility: 2.5 mg/mL (0.68 mM); Suspended solution; Need ultrasonic

此方案可获得 2.5 mg/mL (0.68 mM) 的均匀悬浊液，悬浊液可用于口服和腹腔注射。

以 1 mL 工作液为例，取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900 μL 20% 的 SBE-β-CD 生理盐水水溶液中，混合均匀。

将 2 g 磺丁基醚 β-环糊精加入 5 mL 生理盐水中，再用生理盐水定容至 10 mL，完全溶解，澄清透明
2.

请依序添加每种溶剂：;10% DMSO ;; 90% corn oil

Solubility: ≥ 2.5 mg/mL (0.68 mM); Clear solution

此方案可获得 ≥ 2.5 mg/mL (0.68 mM，饱和度未知) 的澄清溶液，此方案不适用于实验周期在半个月以上的实验。

以 1 mL 工作液为例，取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900 μL玉米油中，混合均匀。

*以上所有助溶剂都可在 MCE 网站选购。

参考文献

[1]. L S Hansen, et al. N-terminally and C-terminally truncated forms of glucose-dependent insulinotropic polypeptide are high-affinity competitive antagonists of the human GIP receptor. Br J Pharmacol. 2016 Mar;173(5):826-38.

Anti GIP (Total) mAb 品牌：Cosmo Bio

发表于2024年2月26日由Whatman官网

Anti GIP (Total) mAb

品牌：Cosmo Bio
CAS No.：
储存条件：-70℃
纯度：–

产品编号 (生产商编号)	等级	规格	运输包装	零售价(RMB)	库存情况	参考值
YII-YM020-EX	–	50 µg	–	咨询	–	–

* 干冰运输、大包装及大批量的产品需酌情添加运输费用

* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动，恕不另行通知，确切详情请联系上海金畔生物科技有限公司。

Anti GIP (Active) mAb 品牌：Cosmo Bio

发表于2024年2月26日由Whatman官网

Anti GIP (Active) mAb

品牌：Cosmo Bio
CAS No.：
储存条件：-70℃
纯度：–

产品编号 (生产商编号)	等级	规格	运输包装	零售价(RMB)	库存情况	参考值
YII-YM021-EX	–	50 µg	–	咨询	–	–

* 干冰运输、大包装及大批量的产品需酌情添加运输费用

GIP (3-42), human

发表于2024年1月16日由Whatman官网

GIP (3-42), human; 纯度: 98.24%

GIP (3-42), human 充当葡萄糖依赖性促胰岛素多肽 (GIP) 受体拮抗剂，在体内调节胰岛素分泌和 GIP 的代谢作用。

GIP (3-42), human Chemical Structure

CAS No. : 1802086-25-4

规格	价格	是否有货	数量
1 mg	￥2100	In-stock
5 mg	￥6200	In-stock
10 mg	￥9900	In-stock
50 mg	;	询价	;
100 mg	;	询价	;

* Please select Quantity before adding items.

GIP (3-42), human 相关产品

bull;相关化合物库:

Bioactive Compound Library Plus
Peptide Library

生物活性

GIP (3-42), human acts as a glucose-dependent insulinotropic polypeptide (GIP) receptor antagonist, moderating the insulin secreting and metabolic actions of GIP in vivo^[1].

体外研究
(In Vitro)

The incretin hormone GIP is rapidly degraded in the circulation by dipeptidyl peptidase IV (DPP IV) forming the N-terminally truncated peptide GIP(3-42)^[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

4749.40

Formula

C₂₁₄H₃₂₄N₅₈O₆₃S

CAS 号

1802086-25-4

Sequence

Glu-Gly-Thr-Phe-Ile-Ser-Asp-Tyr-Ser-Ile-Ala-Met-Asp-Lys-Ile-His-Gln-Gln-Asp-Phe-Val-Asn-Trp-Leu-Leu-Ala-Gln-Lys-Gly-Lys-Lys-Asn-Asp-Trp-Lys-His-Asn-Ile-Thr-Gln

Sequence Shortening

EGTFISDYSIAMDKIHQQDFVNWLLAQKGKKNDWKHNITQ

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Protect from light, stored under nitrogen

Powder	-80deg;C	2 years
	-20deg;C	1 year

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (protect from light, stored under nitrogen)

Solvent Solubility

In Vitro:;

H₂O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

;	Contents	Assign value
Acidic amino acid	Asp (D), Glu (E), and the C-terminal -COOH.	-1
Basic amino acid	Arg (R), Lys (K), His (H), and the N-terminal -NH₂	+1
Neutral amino acid	Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q)	0

3.;;Recommended solution:

Overall charge of peptide	Details
Negative (lt;0)	1.;;Try to dissolve the peptide in water first. 2.;;If water fails, add NH₄OH (lt;50 μL). 3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0)	1.;;Try to dissolve the peptide in water first. 2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution. 3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0)	1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first. 2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.

参考文献

[1]. V A Gault, et al. Evidence that the major degradation product of glucose-dependent insulinotropic polypeptide, GIP(3-42), is a GIP receptor antagonist in vivo. J Endocrinol. 2002 Nov;175(2):525-33.

Medum B for GIP secreting primary culture cell: containing 5.6 mM Glucose 品牌：Reprocell

发表于2023年12月15日由Whatman官网

Medum B for GIP secreting primary culture cell: containing 5.6 mM Glucose

品牌：Reprocell
CAS No.：
储存条件：2-10℃
纯度：–

产品编号 (生产商编号)	等级	规格	运输包装	零售价(RMB)	库存情况	参考值
306-33761	–	100 ml	–	咨询	–	–

* 干冰运输、大包装及大批量的产品需酌情添加运输费用

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标签归档：gip

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