标签归档：fwll

K-(D-1-Nal)-FwLL-NH2

发表于由

K-(D-1-Nal)-FwLL-NH2;

K-(D-1-Nal)-FwLL-NH2 是一种高亲和力、强效、反向的 ghrelin receptor 激动剂 (EC50=3.4 nM； Ki=4.9 nM)。K-(D-1-Nal)-FwLL-NH2 可用于肥胖研究。

K-(D-1-Nal)-FwLL-NH2amp;;

K-(D-1-Nal)-FwLL-NH2 Chemical Structure

CAS No. : 1394288-22-2

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

K-(D-1-Nal)-FwLL-NH2 is a high affinity, potent and inverse ghrelin receptor agonist (EC50=3.4 nM, Ki=4.9 nM). K-(D-1-Nal)-FwLL-NH2 can be used for the research of obesity[1].

IC50 Target

EC50: 3.4 nM (ghrelin receptor), Ki: 4.9 nM (ghrelin receptor)[1]
分子量

902.13

Formula

C51H67N9O6
CAS 号

1394288-22-2
Sequence Shortening

K{Nal}FWLL-NH2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Els S, et al. An aromatic region to induce a switch between agonism and inverse agonism at the ghrelin receptor. J Med Chem. 2012;55(17):7437-7449.

K-(D-1-Nal)-FwLL-NH2 TFA

发表于由

K-(D-1-Nal)-FwLL-NH2 TFA;

K-(D-1-Nal)-FwLL-NH2 TFA is a high affinity and potent ghrelin receptor inverse agonist (Ki values are 4.9 and 31 nM in COS7 and HEK293T cells, respectively). K-(D-1-Nal)-FwLL-NH2 blocks ghrelin receptor-mediated Gq- and G13-dependent signaling pathways.

K-(D-1-Nal)-FwLL-NH2 TFAamp;;

K-(D-1-Nal)-FwLL-NH2 TFA Chemical Structure

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

K-(D-1-Nal)-FwLL-NH2 TFA is a high affinity and potent ghrelin receptor inverse agonist (Ki values are 4.9 and 31 nM in COS7 and HEK293T cells, respectively). K-(D-1-Nal)-FwLL-NH2 blocks ghrelin receptor-mediated Gq- and G13-dependent signaling pathways.

分子量

1016.15

Formula

C53H68F3N9O8
Sequence Shortening

K{Nal}FWLL-NH2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.