生化分析试剂 Biochemical Assay Reagents
Evans Blue;(Synonyms: 伊文思蓝; Direct Blue 53; C.I. 23860) 纯度: ge;95.0%
Evans Blue是一种有效的L-谷氨酸摄取抑制剂, 通过膜结合的兴奋性氨基酸转运蛋白 (EAAT)。能够对抗AMPA红藻氨酸受体介导的电流 (IC50值分别是220和150 nM), 高亲和力与血清白蛋白结合。
Evans Blue Chemical Structure
CAS No. : 314-13-6
规格 | 价格 | 是否有货 | 数量 |
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10;mM;*;1 mL in DMSO | ¥550 | In-stock | |
100 mg | ¥500 | In-stock | |
200 mg | ; | 询价 | ; |
500 mg | ; | 询价 | ; |
* Please select Quantity before adding items.
Evans Blue 相关产品
bull;相关化合物库:
- Drug Repurposing Compound Library Plus
- FDA-Approved Drug Library Plus
- FDA-Approved Drug Library Mini
- Bioactive Compound Library Plus
- FDA-Approved Drug Library
- Peptidomimetic Library
- Drug Repurposing Compound Library
- FDA Approved amp; Pharmacopeial Drug Library
生物活性 |
Evans Blue is a potent inhibitor of L-glutamate uptake via the membrane bound excitatory amino acid transporter (EAAT). Able to antagonize AMPA and kainate receptor mediated currents (IC50 values are 220 and 150 nM, respectively). IC50 value: 220/150 nM Target: L-glutamate uptake receptor Evans blue is a biological dye, for detection of cell survival. Evans Blue can not penetrate healthy cell membrane, but can penetrate into death cell. Binds with high affinity to serum albumin. |
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分子量 |
960.81 |
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Formula |
C34H24N6Na4O14S4 |
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CAS 号 |
314-13-6 |
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中文名称 |
伊文氏蓝;伊文思蓝;埃文斯蓝 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
4deg;C, sealed storage, away from moisture *In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture) |
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溶解性数据 |
In Vitro:;
H2O : 33.33 mg/mL (34.69 mM; Need ultrasonic) DMSO : ≥ 25 mg/mL (26.02 mM) * “≥” means soluble, but saturation unknown. 配制储备液
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
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