标签归档：corn

Trypsin, Bovine, recombinant expressed in Corn 牛胰蛋白酶 品牌：FUJIFILM Wako

发表于由

Trypsin, Bovine, recombinant expressed in Corn

牛胰蛋白酶

品牌：FUJIFILM Wako
CAS No.：9002-07-7
储存条件：-20℃
纯度：–
产品编号

(生产商编号)

 等级 规格 运输包装 零售价(RMB) 库存情况 参考值

204-15933

 – 50 mg –

Trypsin, Bovine, recombinant expressed in Corn 牛胰蛋白酶 品牌：FUJIFILM Wako

 – –


* 干冰运输、大包装及大批量的产品需酌情添加运输费用


* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动，恕不另行通知，确切详情请联系上海金畔生物科技有限公司。

Trypsin, Bovine, recombinant expressed in Corn 牛胰蛋白酶 品牌：FUJIFILM Wako

发表于由

Trypsin, Bovine, recombinant expressed in Corn

牛胰蛋白酶

品牌：FUJIFILM Wako
CAS No.：9002-07-7
储存条件：-20℃
纯度：–
产品编号

(生产商编号)

 等级 规格 运输包装 零售价(RMB) 库存情况 参考值

208-15931

 – 5 mg –

Trypsin, Bovine, recombinant expressed in Corn 牛胰蛋白酶 品牌：FUJIFILM Wako

 – –


* 干冰运输、大包装及大批量的产品需酌情添加运输费用


* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动，恕不另行通知，确切详情请联系上海金畔生物科技有限公司。

Corn oil(Synonyms: 玉米油)

发表于由

生化分析试剂 Biochemical Assay Reagents
Corn oil;(Synonyms: 玉米油)

Corn oil 是从玉米胚芽中提取出来的一种油，可作为药物分子的载体。

Corn oil(Synonyms: 玉米油)

Corn oil Chemical Structure

CAS No. : 8001-30-7

规格 价格 是否有货 数量
50 mL ￥550 In-stock
100 mL ￥800 In-stock
500 mL ￥2700 In-stock
600 mL ￥3150 In-stock
1L ￥4650 In-stock
5L ; 询价 ;
10L ; 询价 ;

* Please select Quantity before adding items.

生物活性

Corn oil, extracted from the germ of corn, can be used as a carrier for drug molecules.

体内研究
(In Vivo)

Corn oil-gavaged rats have 54% lower serum growth hormone (GH) levels, and replacement of GH into corn oil-gavaged rats by osmotic minipump infusion increase in situ MNCL cell proliferation to rates observed in water-gavaged animals[1].
Corn oil is commonly used as a feed additive or a delivery vehicle for lipophilic substances In an animal research setting[3].
Corn oil can become contaminated and cause death/systemic infections several days after IP injections, so corn oil should be aliquoted and frozen (recommendation); thaw and make fresh solution each time.
Corn oil is more recommended for gavage administration[4].
Intraperitoneal oil application causes local inflammation with depletion of resident peritoneal macrophages[5].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Female C57BL/6J mice (n = 90; age, 6 to 7 wk)[3]
Dosage: 0.1 mL.
Administration: Intraperitoneal injection every 48 h for a total of 4 injections over a 7-d period.
Result: At day 21, pharmaceutical-grade (PG) corn oil had a significantly higher pathology score compared with nonpharmaceutical-grade corn oil. No other significant differences between the corn oil groups were observed. The use of nonpharmaceutical grade corn oil did not result in adverse clinical consequences and is presumed safe to use for intraperitoneal injection in mice.

CAS 号

8001-30-7
中文名称

玉米油
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Pure form -20deg;C 3 years
4deg;C 2 years
参考文献

  • [1]. Hursting SD, et al. Inhibition of rat mononuclear cell leukemia by corn oil gavage: in vivo, in situ and immune competence studies. Carcinogenesis. 1994 Feb;15(2):193-9.

    [2]. Gilbertson JR, et al. Inhibition of growth of Morris hepatomas 7777 and 7800 by corn oil. Oncology. 1977;34(2):62-4.

    [3]. Jennifer S Hubbard, et al. Effects of Repeated Intraperitoneal Injection of Pharmaceutical-grade and Nonpharmaceutical-grade Corn Oil in Female C57BL/6J Mice. J Am Assoc Lab Anim Sci. 2017 Nov 1;56(6):779-785.

    [4]. Administration Of Drugs and Experimental Compounds in Mice and Rats

    [5]. Elisenda Alsina-Sanchis, et al. Intraperitoneal Oil Application Causes Local Inflammation with Depletion of Resident Peritoneal Macrophages. Mol Cancer Res. 2021 Feb;19(2):288-300.

DFHO

发表于由

DFHO;

DFHO 是 Corn 荧光适体的荧光配体。RNA 适体, Corn 结合 DFHO 的 Kd 值为 70 nM，并将其转化为荧光形式，从而使 RNA 在细胞中成像。

DFHOamp;;

DFHO Chemical Structure

CAS No. : 1420815-34-4

规格 是否有货
1 mg 询价

* Please select Quantity before adding items.

生物活性

DFHO is a fluorogenic ligand of Corn fluorogenic aptamer. The RNA aptamer, Corn binds DFHO with a Kd value of 70 nM and converts it to a fluorescent form, enabling RNA imaging in cells[1][2].

IC50 Target

Kd: 70 nM (Corn binds DFHO)[1]
体外研究
(In Vitro)

Corn is tested in E. coli. Minimal fluorescence that is seen in DFHO-treated cells (20 μM) transformed with the empty vector. However robust yellow fluorescence is seen in E. coli expressing Corn[1].
Corn-DFHO exhibits markedly enhanced photostability in vitro. The Corn-DFHO complexes are imaged in mammalian cells. Since the U6 promoter is one of the three major Pol III promoters, Corn from the U6 promoter is expressed and replaced the majority of the U6 sequence with Corn, leaving a minimal 5′ capping element leader sequence. The majority of the cells expressed diffuse yellow fluorescence, most prominently in the cytoplasm)[1].
DFHO exhibits low background fluorescence and cytotoxicity, making it a potentially suitable fluorophore for activation by RNA aptamers and for imaging experiments in living cells[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

281.21

Formula

C12H9F2N3O3
CAS 号

1420815-34-4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Wenjiao Song, et al. Imaging RNA polymerase III transcription using a photostable RNA-fluorophore complex. Nat Chem Biol. 2017 Nov;13(11):1187-1194.

    [2]. Hyaeyeong Kim, et al. A Fluorogenic RNA-Based Sensor Activated by Metabolite-Induced RNA Dimerization. Cell Chem Biol. 2019 Dec 19;26(12):1725-1731.e6.