标签归档：cef

CEF14, EBV Rta Protein (28-37)

发表于由

CEF14, EBV Rta Protein (28-37);

CEF14, EBV Rta Protein (28-37) 来自 Epstein-Barr 病毒 Rta 蛋白的 HLA A24 限制性表位。

CEF14, EBV Rta Protein (28-37)amp;;

CEF14, EBV Rta Protein (28-37) Chemical Structure

CAS No. : 216862-58-7

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

CEF14, EBV Rta Protein (28-37) is the HLA A24-restricted epitope from Epstein-Barr Virus Rta protein (28-37).

分子量

1244.37

Formula

C55H81N13O18S
CAS 号

216862-58-7
Sequence

Asp-Tyr-Cys-Asn-Val-Leu-Asn-Lys-Glu-Phe
Sequence Shortening

DYCNVLNKEF
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.

CEF8, Influenza Virus NP (383-391)

发表于由

CEF8, Influenza Virus NP (383-391);

CEF8, Influenza Virus NP (383-391)，一种含有 383-391 残基的甲型流感病毒核蛋白，是甲型流感病毒核蛋白中最重要的 HLA-B*2705 限制性表位，与细胞毒性 T 淋巴细胞介导的免疫逃逸有关。

CEF8, Influenza Virus NP (383-391)amp;;

CEF8, Influenza Virus NP (383-391) Chemical Structure

CAS No. : 142479-13-8

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

CEF8, Influenza Virus NP (383-391), an influenza A virus nucleoprotein containing residues 383 to 391, is the most important HLA-B*2705-restricted epitope in the nucleoprotein of influenza A viruses and is associated with escape from cytotoxic T lymphocytes-mediated immunity[1][2].

分子量

1208.40

Formula

C54H85N19O13
CAS 号

142479-13-8
Sequence Shortening

SRYWAIRTR
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Berkhoff EG, et al. A mutation in the HLA-B*2705-restricted NP383-391 epitope affects the human influenza A virus-specific cytotoxic T-lymphocyte response in vitro. J Virol. 2004 May;78(10):5216-22.

CEF7, Influenza Virus NP (380-388)

发表于由

CEF7, Influenza Virus NP (380-388);

CEF7, Influenza Virus NP (380-388) 是一种 HLA-B*08 限制性流感病毒核蛋白表位。Influenza virus NP 在病毒和宿主细胞过程中起着关键的衔接分子的作用。

CEF7, Influenza Virus NP (380-388)amp;;

CEF7, Influenza Virus NP (380-388) Chemical Structure

CAS No. : 147100-46-7

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

CEF7, Influenza Virus NP (380-388) is a HLA-B*08 restricted influenza virus nucleoprotein epitope. Influenza virus NP functions as a key adapter molecule between virus and host cell processes[1][2].

分子量

1193.35

Formula

C55H84N16O14
CAS 号

147100-46-7
Sequence Shortening

ELRSRYWAI
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Portela A, et al. The influenza virus nucleoprotein: a multifunctional RNA-binding protein pivotal to virus replication. J Gen Virol. 2002 Apr;83(Pt 4):723-34.

    [2]. Boon AC, et al. The magnitude and specificity of influenza A virus-specific cytotoxic T-lymphocyte responses in humans is related to HLA-A and -B phenotype. J Virol. 2002 Jan;76(2):582-90.

CEF20

发表于由

CEF20;

CEF20 是来自巨细胞病毒 pp65（495-503）的 HLA-A*0201 限制性表位。

CEF20amp;;

CEF20 Chemical Structure

CAS No. : 153045-21-7

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

CEF20 is an HLA-A*0201-restricted epitope from cytomegalovirus pp65 (495-503).

分子量

943.16

Formula

C42H74N10O12S
CAS 号

153045-21-7
Sequence

Asn-Leu-Val-Pro-Met-Val-Ala-Thr-Val
Sequence Shortening

NLVPMVATV
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

CEF1, Influenza Matrix Protein M1 (58-66)

发表于由

CEF1, Influenza Matrix Protein M1 (58-66);

CEF1, Influenza Matrix Protein M1 (58-66) 是源于甲型流感病毒 (influenza A virus) 的基质蛋白表位。

CEF1, Influenza Matrix Protein M1 (58-66)amp;;

CEF1, Influenza Matrix Protein M1 (58-66) Chemical Structure

CAS No. : 141368-69-6

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

CEF1, Influenza Matrix Protein M1 (58-66) is an epitope derived from the matrix protein of the influenza A virus[1].

分子量

966.17

Formula

C49H75N9O11
CAS 号

141368-69-6
Sequence

Gly-Ile-Leu-Gly-Phe-Val-Phe-Thr-Leu
Sequence Shortening

GILGFVFTL
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Petrova GV, et al. Cross-reactive responses to modified M1₅₈-₆₆ peptides by CD8⁺ T cells that use noncanonical BV genes can describe unknown repertoires. Eur J Immunol. 2012 Nov;42(11):3001-8.

CEF3

发表于由

CEF3;

CEF3 (SIIPSGPLK) 对应于甲型流感病毒M1蛋白的13-21氨基酸序列。甲型流感病毒M1蛋白是一种多功能蛋白质，在病毒生命周期中起着重要的结构和功能作用。

CEF3amp;;

CEF3 Chemical Structure

CAS No. : 199727-62-3

规格 价格 是否有货
1 mg ￥1200 询问价格 货期
5 mg ￥4800 询问价格 货期
10 mg ￥8100 询问价格 货期

* Please select Quantity before adding items.

生物活性

CEF3 (SIIPSGPLK) corresponds to aa 13-21 of the influenza A virus M1 protein. The matrix (M1) protein of influenza A virus is a multifunctional protein that plays essential structural and functional roles in the virus life cycle.

体外研究
(In Vitro)

The matrix (M1) protein of influenza A virus is a multifunctional protein that plays essential structural and functional roles in the virus life cycle. It drives virus budding and is the major protein component of the virion, where it forms an intermediate layer between the viral envelope and integral membrane proteins and the genomic ribonucleoproteins (RNPs). It also helps to control the intracellular trafficking of RNPs. These roles are mediated primarily via protein-protein interactions with viral and possibly cellular proteins[1]. The influenza virus M1 is required to induce vRNP nuclear export but that cellular phosphorylation is an additional factor. The influenza virus M1 protein is fundamental to a late event in the virus life cycle-the transfer of vRNPs from the nucleus to the cytosol[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

911.10

Formula

C42H74N10O12
CAS 号

199727-62-3
Sequence

Ser-Ile-Ile-Pro-Ser-Gly-Pro-Leu-Lys
Sequence Shortening

SIIPSGPLK
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Noton SL, et al. Identification of the domains of the influenza A virus M1 matrix protein required for NP binding, oligomerization and incorporation into virions. J Gen Virol. 2007 Aug;88(Pt 8):2280-90.

    [2]. Bui M, et al. Role of the influenza virus M1 protein in nuclear export of viral ribonucleoproteins. J Virol. 2000 Feb;74(4):1781-6.

CEF4

发表于由

CEF4;

CEF4 是一种多肽，它与甲型流感病毒核衣壳蛋白的第 342-351 位氨基酸序列相对应。

CEF4amp;;

CEF4 Chemical Structure

CAS No. : 199727-68-9

规格 价格 是否有货
1 mg ￥800 询问价格 货期
5 mg ￥3200 询问价格 货期
10 mg ￥5600 询问价格 货期

* Please select Quantity before adding items.

生物活性

CEF4 is a peptide that corresponds to aa 342-351 of the influenza A virus nucleocapsid protein.

分子量

1148.40

Formula

C53H93N15O13
CAS 号

199727-68-9
Sequence

Arg-Val-Leu-Ser-Phe-Ile-Lys-Gly-Thr-Lys
Sequence Shortening

RVLSFIKGTK
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.

CEF6

发表于由

CEF6;

CEF6 是由 9 个氨基酸构成的多肽，与流感病毒 H1N1 的核衣壳蛋白的第 418-426 位氨基酸序列相对应。

CEF6amp;;

CEF6 Chemical Structure

CAS No. : 913545-15-0

规格 价格 是否有货
1 mg ￥600 询问价格 货期
5 mg ￥1800 询问价格 货期
10 mg ￥2800 询问价格 货期

* Please select Quantity before adding items.

生物活性

CEF6 is a 9-aa-long peptide corresponding to aa 418-426 of the influenza A virus (H1N1) nucleocapsid protein.

分子量

1051.26

Formula

C48H78N10O14S1
CAS 号

913545-15-0
Sequence

Leu-Pro-Phe-Asp-Lys-Thr-Thr-Val-Met
Sequence Shortening

LPFDKTTVM
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Yu K, et al. shRNA?mediated NP knockdown inhibits the apoptosis of cardiomyocytes induced by H1N1pdm2009 influenza virus. Mol Med Rep. 2017 Aug;16(2):1376-1382.