Camellianin A(Synonyms: 山茶黄酮苷 A)

天然产物糖类和糖苷 Saccharides and Glycosides

Camellianin A;(Synonyms: 山茶黄酮苷 A)

Camellianin A 是 A. nitida 叶中主要的黄酮类化合物，具有抗癌活性和抗血管紧张素转换酶 (ACE) 活性。Camellianin A 能抑制人 Hep G2 和 MCF-7 细胞的增殖，诱导细胞 G0/G1 期停滞。

Camellianin A Chemical Structure

CAS No. : 109232-77-1

规格	价格	是否有货
1 mg	￥1900	询问价格货期
5 mg	￥5710	询问价格货期

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生物活性	Camellianin A, the main flavonoid in A. nitida leaves, displays anticancer activity and angiotensin converting enzyme (ACE)-inhibitory activity. Camellianin A inhibits the proliferation of the human Hep G2 and MCF-7 cell lines and induces the significant increase of the G0/G1 cell population^[1]^[2].
分子量	620.56
Formula	C₂₉H₃₂O₁₅
CAS 号	109232-77-1
中文名称	山茶黄酮苷 A；山茶宁 A
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Gao H, et al. Anti-proliferative effect of camellianin A in Adinandra nitida leaves and its apoptotic induction in human Hep G2 and MCF-7 cells. Molecules. 2010 May 28;15(6):3878-86. [2]. Liu B, et al. Antioxidant and angiotensin converting enzyme (ACE) inhibitory activities of ethanol extract and pure flavonoids from Adinandra nitida leaves. Pharm Biol. 2010 Dec;48(12):1432-8.

Camellianin B(Synonyms: 山茶黄酮苷 B)

天然产物黄酮类 Flavonoids

Camellianin B (Synonyms: 山茶黄酮苷 B)

Camellianin B，是一种黄酮类化合物，是 Camellianin A 的代谢物。Camellianin B 具有抗氧化和血管紧张素转化酶 (ACE) 抑制活性。

Camellianin B Chemical Structure

CAS No. : 109232-76-0

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生物活性	Camellianin B, a flavonoid compound, is a Camellianin A metabolite. Camellianin B has antioxidant and angiotensin converting enzyme (ACE) inhibitory activities^[1]^[2].
体外研究 (In Vitro)	At 500 μg/mL, the ACE inhibitory activities of Camellianin B is 40.68%. Camellianin B has DPPH radical scavenging activity with IC₅₀ value of 1.8 mg/mL^[2]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究 (In Vivo)	Camellianin B has a wide tissue distribution with brain penetration^[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量	578.52
Formula	C₂₇H₃₀O₁₄
CAS 号	109232-76-0
中文名称	山茶黄酮苷 B
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Yunliang Zheng, et al. Pharmacokinetics and tissue distribution study of camellianin A and its major metabolite in rats by liquid chromatography with tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Aug 1;997:200-9. [2]. Benguo Liu, et al. Antioxidant and angiotensin converting enzyme (ACE) inhibitory activities of ethanol extract and pure flavonoids from Adinandra nitida leaves. Pharm Biol. 2010 Dec;48(12):1432-8.