标签归档：blue

Procion Blue HB(Synonyms: 蓝色染料 Reactive Blue 2)

发表于由

Procion Blue HB;(Synonyms: 蓝色染料; Reactive Blue 2)

Procion Blue HB (Reactive Blue 2)是嘌呤能拮抗剂。

Procion Blue HBamp;;(Synonyms: 蓝色染料; Reactive Blue 2)

Procion Blue HB Chemical Structure

CAS No. : 12236-82-7

规格 价格 是否有货
10;mM;*;1 mL in DMSO ￥550 询问价格 货期
10 mg ￥500 询问价格 货期
50 mg ￥1500 询问价格 货期
100 mg ￥1900 询问价格 货期

* Please select Quantity before adding items.

Procion Blue HB 相关产品

bull;相关化合物库:

  • Anti-Cardiovascular Disease Compound Library
  • Natural Product Like Compound Library
  • Bioactive Compound Library Plus

生物活性

Procion Blue HB (Reactive Blue 2) is a purinergic antagonist.

体外研究
(In Vitro)

Reactive Blue 2 is used as an ATP receptor antagonist and induces Ca2+ oscillations in HeLa cells. Reactive Blue 2 enhances a Ca2+ response to histamine that is linked to the PLC cascade. Reactive Blue 2 may activate the PLC cascade in an extracellular Ca2+-dependent manner and induce Ca2+ oscillations[1]. The application of Reactive Blue 2 increases K+ secretion in a dose-dependent manner, and this increase is characterized as a peak followed by a partial relaxation to a steady-state. Reactive Blue 2 has antagonistic activities at P2Y4, and the antagonist potency at P2Y4 paralleled the potency of K+ secretion[2].The anthraquinone dye reactive blue 2 is found to be a potent inhibitor of a protein kinase isolated and purified from thylakoids. The mode of inhibition is noncompetitive, with a Ki of 8 μM for the membrane-bound kinase, and 6 microM for the purified kinase. The inhibitor does not modify the substrate preference of the endogenous kinase and could be removed from the membrane by washing[3]. Reactive blue 2 selectively inhibits responses mediated via the P2ypurinoceptor, at least within a limited concentration range. In preparations where the tone has been raised with noradrenaline, ATP and 2-methylthio ATP, but not α,β-methylene ATP, produce relaxations of the vessel. These relaxations are inhibited in the presence of reactive blue 2[4]. Reactive blue 2, at concentrations of 0.3-10 μM blocks the ATP-induced oscillation in a concentration-dependent manner[5].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

774.16

Formula

C58H40Cl2N14O22S6
CAS 号

12236-82-7
中文名称

蓝色染料；普施安蓝 HB；活性蓝 2；汽巴蓝 F3GA
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4deg;C, protect from light

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (protect from light)
溶解性数据
In Vitro:;

DMSO : ≥ 110 mg/mL (142.09 mM)

H2O : 10 mg/mL (12.92 mM; Need ultrasonic)

Ethanol : < 1 mg/mL (insoluble)

* “≥” means soluble, but saturation unknown.

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.2917 mL 6.4586 mL 12.9172 mL
5 mM 0.2583 mL 1.2917 mL 2.5834 mL
10 mM 0.1292 mL 0.6459 mL 1.2917 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Okuda A, et al. Reactive blue 2 induces calcium oscillations in HeLa cells. Jpn J Physiol. 2001 Jun;51(3):389-93.

    [2]. Lee JH, et al. Reactive blue 2, an antagonist of rat P2Y4, increases K+ secretion in rat cochlea strial marginal cells. Hear Res. 2006 Sep;219(1-2):66-73.

    [3]. Coughlan SJ, et al. Reactive blue 2 is a potent inhibitor of a thylakoid protein kinase. Eur J Biochem. 1991 Apr 23;197(2):467-71.

    [4]. Burnstock G, et al. P2-purinoceptors of two subtypes in the rabbit mesenteric artery: reactive blue 2 selectively inhibits responses mediated via the P2y-but not the P2x-purinoceptor. Br J Pharmacol. 1987 Feb;90(2):383-91.

    [5]. Uneyama H, et al. Suramin and reactive blue 2 are antagonists for a newly identified purinoceptor on rat megakaryocyte. Br J Pharmacol. 1994 Jan;111(1):245-9.

荧光染料Cibacron Blue 3G-A

发表于由

荧光染料Dye Reagents Cibacron Blue 3G-A;

Cibacron Blue 3G-A 是一种蒽醌染料，可以抑制 R46 β-lactamase，Ki 值为 1.2 uM。

Cibacron Blue 3G-A

Cibacron Blue 3G-A Chemical Structure

CAS No. : 84166-13-2

规格 价格 是否有货
10 mg ￥500 询问价格 货期
25 mg ￥700 询问价格 货期
50 mg ￥900 询问价格 货期
100 mg ￥1500 询问价格 货期

* Please select Quantity before adding items.

生物活性

Cibacron Blue 3G-A is an anthraquinone dye, inhibits the R46 β-lactamase with a Ki value of 1.2 uM[1].

IC50 Target

IC50: anthraquinone dye[1]
体外研究
(In Vitro)

Cibacron Blue 3G-A is a structural analogy between the dye and NADH, it interacts with (di)nucleotide-dependent enzymes and can be a standard tool for studying their active sites[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

774.16

Formula

C29H20ClN7O11S3
CAS 号

84166-13-2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Monaghan C, et al. The interaction of anthraquinone dyes with the plasmid-mediated OXA-2 beta-lactamase.Biochem J. 1982 Aug 1;205(2):413-7.

    [2]. Monaghan C, et al. The interaction of anthraquinone dyes with the plasmid-mediated OXA-2 beta-lactamase.Biochem J. 1982 Aug 1;205(2):413-7.

荧光染料ER-Tracker Blue-White DPX

发表于由

荧光染料Dye Reagents ER-Tracker Blue-White DPX;

ER-Tracker Blue-White DPX 是一种光稳定探针，用于选择性地标记内质网以进行荧光显微镜成像。

ER-Tracker Blue-White DPX

ER-Tracker Blue-White DPX Chemical Structure

CAS No. : 287715-95-1

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

ER-Tracker Blue-White DPX is a photostable probe used to selectively label the endoplasmic reticulum for fluorescence microscopy imaging[1].

分子量

580.53

Formula

C26H21F5N4O4S
CAS 号

287715-95-1
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Corryn E Chini, et al. Observation of endoplasmic reticulum tubules via TOF-SIMS tandem mass spectrometry imaging of transfected cells. Biointerphases. 2018 Feb 26;13(3):03B409.

    [2]. Yun-Mi Jeong, et al. CDy6, a photostable probe for long-term real-time visualization of mitosis and proliferating cells. Chem Biol. 2015 Feb 19;22(2):299-307.

荧光染料Msr-blue

发表于由

荧光染料Dye Reagents Msr-blue; 纯度: 97.36%

Msr-blue 是首个 “Turn-on” 型的甲硫氨酸亚砜还原酶 (methionine sulfoxide reductase) 荧光探针，具有超过 100 倍的荧光增量。Msr-blue 用于监测活细胞中甲硫氨酸亚砜还原酶的活性 (λex=340 nm, λem=440 nm)。

Msr-blueamp;;

Msr-blue Chemical Structure

规格 价格 是否有货 数量
1 mg ￥700 In-stock
5 mg ￥2300 In-stock
10 mg ￥3600 In-stock
50 mg ; 询价 ;
100 mg ; 询价 ;

* Please select Quantity before adding items.

Msr-blue 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus

生物活性

Msr-blue is a first turn-on fluorescent probe for methionine sulfoxide reductase with a more than 100-fold fluorescence increment. Msr-blue is used for monitoring the enzyme activity in live cells (λex=340 nm, λem=440 nm)[1].

体外研究
(In Vitro)

Msr-blue is emited blue fluorescence after activation by methionine sulfoxide reductase A (Msr A). Msr-blue responded to Msr A in both a time- and dose-dependent manner, and more than a 100-fold increase in the emission is observed. Msr-blue is converted to its corresponding sulfide (15′) under catalysis by either the purified Msr A or a cell lysate[1].
The 6-OHDA-treated PC12 cells as a cellular model of Parkinson’s disease (PD) is employed and applied Msr-blue to probe the function of Msrs in the cells. With the aid of Msr-blue, a decline of the Msr activity in a PD model was disclosed for the first time[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

222.26

Formula

C11H10O3S
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20deg;C 3 years
4deg;C 2 years
In solvent -80deg;C 6 months
-20deg;C 1 month
溶解性数据
In Vitro:;

DMSO : 25 mg/mL (112.48 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 4.4992 mL 22.4962 mL 44.9924 mL
5 mM 0.8998 mL 4.4992 mL 8.9985 mL
10 mM 0.4499 mL 2.2496 mL 4.4992 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂：

——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用； 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶

  • 1.

    请依序添加每种溶剂：;10% DMSO ;; 40% PEG300 ;; 5% Tween-80 ;; 45% saline

    Solubility: ≥ 2.5 mg/mL (11.25 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (11.25 mM，饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例，取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中，混合均匀；向上述体系中加入50 μL Tween-80，混合均匀；然后继续加入 450 μL生理盐水定容至 1 mL。

    将 0.9 g 氯化钠，完全溶解于 100 mL ddH₂O 中，得到澄清透明的生理盐水溶液

  • 2.

    请依序添加每种溶剂：;10% DMSO ;; 90% (20% SBE-β-CD in saline)

    Solubility: 2.5 mg/mL (11.25 mM); Suspended solution; Need ultrasonic

    此方案可获得 2.5 mg/mL (11.25 mM) 的均匀悬浊液，悬浊液可用于口服和腹腔注射。

    以 1 mL 工作液为例，取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900 μL 20% 的 SBE-β-CD 生理盐水水溶液中，混合均匀。

    将 2 g 磺丁基醚 β-环糊精加入 5 mL 生理盐水中，再用生理盐水定容至 10 mL，完全溶解，澄清透明
  • 3.

    请依序添加每种溶剂：;10% DMSO ;; 90% corn oil

    Solubility: ≥ 2.5 mg/mL (11.25 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (11.25 mM，饱和度未知) 的澄清溶液，此方案不适用于实验周期在半个月以上的实验。

    以 1 mL 工作液为例，取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900 μL玉米油中，混合均匀。

*以上所有助溶剂都可在 MCE 网站选购。
参考文献

  • [1]. Liangwei Zhang, et al. A specific fluorescent probe reveals compromised activity of methionine sulfoxide reductases in Parkinson’s disease. Chem Sci. 2017 Apr 1;8(4):2966-2972.

Methyl Blue(Synonyms: 甲基蓝)

发表于由

Methyl Blue;(Synonyms: 甲基蓝)

Methyl blue 属于三氨基三苯甲烷染料。Methyl blue 在多色染色法中被广泛用作抗菌染料，并在组织学和微生物学染色溶液中得到应用。Methyl blue 已经用作模型来研究各种催化剂对染料光降解的影响。

Methyl Blueamp;;(Synonyms: 甲基蓝)

Methyl Blue Chemical Structure

CAS No. : 28983-56-4

规格 价格 是否有货 数量
10;mM;*;1 mL in Water ￥610 In-stock
100 mg ￥550 In-stock
200 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

Methyl Blue 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus
  • Anti-Infection Compound Library

生物活性

Methyl blue belongs to the group of triaminotriphenylmethane dyes. Methyl blue is widely used as antiseptic dye in polychrome staining method and has applications in histological and microbiological staining solutions. Methyl blue has been used as a model to study the effect of various catalysts on photodegradation of dyes[1][2].

分子量

799.80

Formula

C37H27N3Na2O9S3
CAS 号

28983-56-4
中文名称

甲基蓝
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4deg;C, sealed storage, away from moisture

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture)
溶解性数据
In Vitro:;

H2O : 20 mg/mL (25.01 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.2503 mL 6.2516 mL 12.5031 mL
5 mM 0.2501 mL 1.2503 mL 2.5006 mL
10 mM 0.1250 mL 0.6252 mL 1.2503 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Mohammed Hassan, et al. Micellar effect on the kinetics of oxidation of methyl blue by Ce(IV) in sulfuric acid medium. Arabian Journal of Chemistry. Volume 8, Issue 1, January 2015, Pages 72-77.

    [2]. K.Kotak, et al. Photostability of Aniline Blue (CI 42755) and Methyl Blue (CI 42780). Dyes and Pigments. Volume 34, Issue 2, June 1997, Pages 159-167.

日本东洋ALB （Alkali blue）PH试纸 动物血清07010080

发表于由

日本东洋ALB （Alkali blue）PH试纸 动物血清

简要描述：

ADVANTEC ALB酸碱测试纸/PH试纸 pH Test Papers

品名：ALB (Alkali blue)

货号：07010080

测试范围pH：11.0 ～ 13.6

包装：书型7mm x 70mm(WxL)20张/册，10册/盒 

卷型9mm x 6M或9mm x 5.5M(WxR)

日本东洋ALB (Alkali blue)PH试纸

订货信息：

日本东洋ALB （Alkali blue）PH试纸 动物血清07010080

Disperse Blue 148(Synonyms: C.I. Disperse Blue 148 C.I. 11124)

发表于由

Disperse Blue 148;(Synonyms: C.I. Disperse Blue 148; C.I. 11124)

Disperse Blue 148是一种蓝色偶氮染料。

Disperse Blue 148amp;;(Synonyms: C.I. Disperse Blue 148; C.I. 11124)

Disperse Blue 148 Chemical Structure

CAS No. : 52239-04-0

规格 价格 是否有货
10;mM;*;1 mL in DMSO ￥880 询问价格 货期
100 mg ￥800 询问价格 货期

* Please select Quantity before adding items.

Disperse Blue 148 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus

生物活性

Disperse Blue 148 is the best high-temperature trichromatic blue azo dye. Target: Single-crystal structures of the best high-temperature trichromatic blue azo dye C.I. Disperse Blue 148 and its diazonium component 3-amino-5-nitro-[2,1]- benzisothiazole are described herein. C.I. Disperse Blue 148 exhibits an essentially coplanar molecular structure and a dimeric packing mode between adjacent phenyl and benzisothiazole rings. Particularly, PXRD measurement reveals the existence of a new crystalline form of C.I. Disperse Blue 148 having the highest melting point and the best thermal stability, which is obviously different from all the known α, β, and γ forms. [1]

分子量

413.45

Formula

C19H19N5O4S
CAS 号

52239-04-0
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4deg;C, protect from light

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (protect from light)
溶解性数据
In Vitro:;

H2O : ≥ 30 mg/mL (72.56 mM)

DMSO : 20 mg/mL (48.37 mM; Need ultrasonic and warming)

* “≥” means soluble, but saturation unknown.

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.4187 mL 12.0934 mL 24.1867 mL
5 mM 0.4837 mL 2.4187 mL 4.8373 mL
10 mM 0.2419 mL 1.2093 mL 2.4187 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Hui-Fen Qian, et al. Structural and spectral characterizations of C.I. Disperse Blue 148 having a new crystalline form. Dyes and Pigments Volume 99, Issue 2, November 2013, Pages 489-495

Brilliant blue G-250

发表于由

生化分析试剂 Biochemical Assay Reagents
Brilliant blue G-250;

Brilliant Blue G-250 是一种常用于 SDS-PAGE 分离蛋白质可视化的染料，染色过程简单，定量高。在 Bradford 蛋白质分析中，由于 Brilliant Blue G-250 与蛋白质结合，蛋白质浓度由 595 nm 处的吸光度确定。Brilliant Blue G-250 是一种安全、高选择性的 P2×7R 拮抗剂，有望使 NLRP3炎症体失活。

Brilliant blue G-250

Brilliant blue G-250 Chemical Structure

CAS No. : 6104-58-1

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

Brilliant Blue G-250 is a dye commonly used for the visualization of proteins separated by SDS-PAGE, offering a simple staining procedure and high quantitation. In the Bradford protein assay, protein concentrations are determined by the absorbance at 595 nm due to the binding of Brilliant Blue G-250 to proteins. Brilliant Blue G-250 is a safe highly selective P2×7R antagonist with promising consequent inactivation of NLRP3 inflammasome[1][2][3].

分子量

854.02

Formula

C47H48N3NaO7S2
CAS 号

6104-58-1
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4deg;C, sealed storage, away from moisture

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture)
参考文献

  • [1]. Dyballa N, Metzger S. Fast and sensitive colloidal coomassie G-250 staining for proteins in polyacrylamide gels. J Vis Exp. 2009;(30):1431. Published 2009 Aug 3.

    [2]. Han XX, et al. Highly sensitive protein concentration assay over a wide range via surface-enhanced Raman scattering of Coomassie brilliant blue. Anal Chem. 2010;82(11):4325-4328.

    [3]. Zohny MH, et al. Coomassie brilliant blue G-250 dye attenuates bleomycin-induced lung fibrosis by regulating the NF-κB and NLRP3 crosstalk: A novel approach for filling an unmet medical need [published online ahead of print, 2022 Feb 21]. Biomed Pharmacother. 2022;148:112723.

Bio-Serv动物模型饲料K3293 Medium, Blue

发表于由

上海金畔生物科技有限公司代理Bio-Serv品牌动物模型饲料全线产品，欢迎访问官网了解更多产品信息。
Bio-Serv动物模型饲料K3293 Medium, Blue

K3293

K3294

K3295

Product Details
  • Blue Kong with attached welded link, stainless steel chain with quick link
    (overall chain length – approximately 5 1/2")
  • Fill with treats to promote mental and physical activity
  • Cagewasher safe
Dimensions
Kong Toy Medium – 3 1/2″ high
Kong Toy Large – 4″ high
Kong Toy XLarge – 5″ high
Chain Length – approximately 5 1/2″
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Bio-Serv动物模型饲料K3283 Small, Blue

发表于由

上海金畔生物科技有限公司代理Bio-Serv品牌动物模型饲料全线产品，欢迎访问官网了解更多产品信息。
Bio-Serv动物模型饲料K3283 Small, Blue

K3283

K3284

K3285

K3287

Product Details
  • Made of natural rubber
  • Visible on radiographs
  • 25% stronger than regular Kongs
  • Fill with treats to promote mental and physical activity
  • Cagewasher safe
Dimensions
Small – 3″ high
Medium – 3 1/2″ high
Large – 4″ high
XLarge – 5″ high
King – 6″ high
Reviews
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Customer Ratings & Reviews

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