标签归档：basic

Fibroblast Growth Factor (basic)(FGF-basic / bFGF / FGF2), Mouse, recombinant, Animal-derived-free 品牌：FUJIFILM Wako

发表于由

Fibroblast Growth Factor (basic)(FGF-basic / bFGF / FGF2), Mouse, recombinant, Animal-derived-free

品牌：FUJIFILM Wako
CAS No.：
储存条件：-20℃
纯度：–
产品编号

(生产商编号)

 等级 规格 运输包装 零售价(RMB) 库存情况 参考值

062-06041

 for Cellbiology 50ug – 4,940.00 – –


* 干冰运输、大包装及大批量的产品需酌情添加运输费用


* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动，恕不另行通知，确切详情请联系上海金畔生物科技有限公司。

FGF-basic 147 (human), (recombinant) 成纤维细胞生长因子碱性147（人），（重组） 品牌：Enzo

发表于由

FGF-basic 147 (human), (recombinant)

成纤维细胞生长因子碱性147（人），（重组）

品牌：Enzo
CAS No.：
储存条件：-20℃
纯度：–
产品编号

(生产商编号)

 等级 规格 运输包装 零售价(RMB) 库存情况 参考值

ALX-201-822-0100

 – 100 µg – 11,940.00 – –


* 干冰运输、大包装及大批量的产品需酌情添加运输费用


* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动，恕不另行通知，确切详情请联系上海金畔生物科技有限公司。

Myelin Basic Protein(87-99) TFA

发表于由

Myelin Basic Protein(87-99) TFA;

Myelin Basic Protein(87-99) TFA 是一种致脑肽，可诱导碱性蛋白特异性 T 细胞增殖。Myelin Basic Protein(87-99) TFA 在外周血单核细胞中引起 Th1 极化，与多发性硬化症 (MS) 有关。

Myelin Basic Protein(87-99) TFAamp;;

Myelin Basic Protein(87-99) TFA Chemical Structure

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

Myelin Basic Protein(87-99) TFA is an encephalitogenic peptide that induces basic protein-specific T cell proliferation. Myelin Basic Protein(87-99) TFA causes a Th1 polarization in peripheral blood mononuclear cells with is implicated of multiple sclerosis (MS)[1][2].

分子量

1669.82

Formula

C76H115N20O19F3
Sequence

Val-His-Phe-Phe-Lys-Asn-Ile-Val-Thr-Pro-Arg-Thr-Pro
Sequence Shortening

VHFFKNIVTPRTP
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. R E Jones, et al. The synthetic 87-99 peptide of myelin basic protein is encephalitogenic in Buffalo rats. J Neuroimmunol. 1992 Apr;37(3):203-12.

    [2]. George Deraos, et al. Citrullination of linear and cyclic altered peptide ligands from myelin basic protein (MBP(87-99)) epitope elicits a Th1 polarized response by T cells isolated from multiple sclerosis patients: implications in triggering disease. J Med Chem. 2008 Dec 25;51(24):7834-42.

Purified Sugi Basic Protein (Japanese Cedar Pollen Allergen) 品牌：Hayashibara

发表于由

Purified Sugi Basic Protein (Japanese Cedar Pollen Allergen)

品牌：Hayashibara
CAS No.：
储存条件：-20℃
纯度：–
产品编号

(生产商编号)

 等级 规格 运输包装 零售价(RMB) 库存情况 参考值

636-32211

 – 200 ug –

Purified Sugi Basic Protein (Japanese Cedar Pollen Allergen) 品牌：Hayashibara

 – –


* 干冰运输、大包装及大批量的产品需酌情添加运输费用


* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动，恕不另行通知，确切详情请联系上海金畔生物科技有限公司。

Myelin Basic Protein(Synonyms: MHP4-14)

发表于由

Myelin Basic Protein;(Synonyms: MHP4-14)

Myelin Basic Protein (MHP4-14) 是一种合成肽，包含髓鞘碱性蛋白的残基4-14，是一种非常有选择性的PKC底物 (Km=7 μM)。Myelin Basic Protein 不被环腺苷酸依赖性蛋白激酶、酪蛋白激酶 I 和 II、Ca2+/钙调素依赖性蛋白激酶II或磷酸化酶激酶磷酸化，可常规用于测定粗组织提取物中低背景的蛋白激酶C。

Myelin Basic Proteinamp;;(Synonyms: MHP4-14)

Myelin Basic Protein Chemical Structure

CAS No. : 126768-94-3

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

Myelin Basic Protein 的其他形式现货产品:

Myelin Basic Protein TFA

生物活性

Myelin Basic Protein (MHP4-14), a synthetic peptide comprising residues 4-14 of myelin basic protein, is a very selective PKC substrate (Km=7 μM). Myelin Basic Protein is not phosphorylated by cyclic AMP-dependent protein kinase, casein kinases I and II, Ca2+/calmodulin-dependent protein kinase II, or phosphorylase kinase, and can be routinely used for the assay of protein kinase C with low background in the crude tissue extracts[1][2].

体外研究
(In Vitro)

Once MBP4-14 is phosphorylated, it is not dephosphorylated by okadaic acid-sensitive phosphatases (protein phosphatases 1, 2A and 3) or other protein phosphatases such as calcineurin and/or PP 2C present in hippocampal homogenates. Therefore, MBP4-14 can be used for PKC assay in crude extracts of neural tissue[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

1390.59

Formula

C60H103N21O17
CAS 号

126768-94-3
Sequence

Gln-Lys-Arg-Pro-Ser-Gln-Arg-Ser-Lys-Tyr-Leu
Sequence Shortening

QKRPSQRSKYL
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. Farrar YJ, et al. A phosphatase resistant substrate for the assay of protein kinase C in crude tissue extracts. Biochem Biophys Res Commun. 1991;180(2):694-701.

    [2]. Yasuda I, et al. A synthetic peptide substrate for selective assay of protein kinase C. Biochem Biophys Res Commun. 1990;166(3):1220-1227.

Methylene Blue(Synonyms: 亚甲蓝 Basic Blue 9 CI-52015 Methylthioninium chloride)

发表于由

Methylene Blue;(Synonyms: 亚甲蓝; Basic Blue 9; CI-52015; Methylthioninium chloride) 纯度: ge;98.0%

Methylene blue (Basic Blue 9) 是一种鸟苷酸环化酶 (sGC)，单胺氧化酶 A (MAO-A) 和 NO 合酶 (NOS) 抑制剂。Methylene blue 是一种血管加压剂，在医疗中通常用作染料。Methylene blue 具有抗伤害感受，抗疟疾，抗抑郁和抗焦虑作用，可用于高铁血红蛋白血症，神经退行性疾病和异环磷酰胺引起的脑病的研究。

Methylene Blueamp;;(Synonyms: 亚甲蓝; Basic Blue 9; CI-52015; Methylthioninium chloride)

Methylene Blue Chemical Structure

CAS No. : 61-73-4

规格 价格 是否有货 数量
Free Sample (0.1-0.5 mg) ; Apply now ;
100 mg ￥500 In-stock
500 mg ￥850 In-stock
1 g ; 询价 ;
5 g ; 询价 ;

* Please select Quantity before adding items.

Methylene Blue 相关产品

bull;相关化合物库:

  • Drug Repurposing Compound Library Plus
  • FDA-Approved Drug Library Plus
  • Bioactive Compound Library Plus

生物活性

Methylene blue (Basic Blue 9) is a guanylyl cyclase (sGC), monoamine oxidase A (MAO-A) and NO synthase (NOS) inhibitor. Methylene blue is a vasopressor and is often used as a dye in several medical procedures. Methylene blue has antinociception, antimalarial, antidepressant and anxiolytic activity effects. Methylene Blue has the potential for methemoglobinemias, neurodegenerative disorders and ifosfamide-induced encephalopathytreatment[1][2][3].

IC50 Target

Guanylyl cyclase (sGC)[1].
Monoamine oxidase A (MAO-A)[1].
NO synthase (NOS)[1]
体外研究
(In Vitro)

By acting as an alternative electron acceptor/donor Methylene blue restores mitochondrial function, improves neuronal energy production and inhibits the formation of superoxide[1].
Methylene blue inhibits cytochrome P450 (CYP) isozymes. Methylene blue is an odorless, water soluble, dark blue-green crystalline powder, which turns blue whenever mixed in solution. Methylene blue is a vasopressor that impacts the NO synthetic pathway by inhibiting inducible NOS and inhibiting the subsequent activation of sGC. In addition, by binding to the iron heme moiety of sGC and causing enzyme inhibition, Methylene blue blocks accumulation of cyclic GMP (cGMP), competing directly with NO in its ability to activate soluble guanylyl cyclase[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究
(In Vivo)

Methylene Blue (1, 5, and 25 μg/rat) significantly decreases sevoflurane minimum alveolar anesthetic concentration (MAC) and brain cyclic guanosine monophosphate (cGMP) content in a dose-dependent manner in male Sprague-Dawley rats (7-week-old, 200-250 g)[2].
Methylene blue is used as a dye in chromoendoscopy, and is sprayed onto the mucosa of the gastrointestinal tract in order to identify dysplasia, or pre-cancerous lesions[2].
Methylene blue is able to restore vascular tone, normalize mean arterial pressures (MAP), and reduce vasopressor usage[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial

分子量

319.85

Formula

C16H18ClN3S
CAS 号

61-73-4
中文名称

亚甲蓝
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4deg;C, sealed storage, away from moisture

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture)
溶解性数据
In Vitro:;

H2O : ≥ 50 mg/mL (156.32 mM)

* “≥” means soluble, but saturation unknown.

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 3.1265 mL 15.6323 mL 31.2647 mL
5 mM 0.6253 mL 3.1265 mL 6.2529 mL
10 mM 0.3126 mL 1.5632 mL 3.1265 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Delport A, et al. Methylene blue and its analogues as antidepressant compounds. Metab Brain Dis. 2017 Oct;32(5):1357-1382.

    [2]. Masaki E, et al. Methylene blue, a soluble guanylyl cyclase inhibitor, reduces the sevoflurane minimum alveolar anesthetic concentration and decreases the brain cyclic guanosine monophosphate content in rats. Anesth Analg. 1999 Aug;89(2):484-9.

    [3]. McCartney SL, et al. Intraoperative vasoplegia: methylene blue to the rescue! Curr Opin Anaesthesiol. 2018 Feb;31(1):43-49.

Crystal Violet(Synonyms: 结晶紫 Basic Violet 3 Gentian Violet Methyl Violet 10B)

发表于由

Crystal Violet;(Synonyms: 结晶紫; Basic Violet 3; Gentian Violet; Methyl Violet 10B) 纯度: 95.54%

Crystal violet (Basic Violet 3) 是革兰氏染色染料。Crystal Violet (Gentian Violet) 对 H1N1 具有抗病毒作用，并且具有显着的杀菌活性。

Crystal Violetamp;;(Synonyms: 结晶紫; Basic Violet 3; Gentian Violet; Methyl Violet 10B)

Crystal Violet Chemical Structure

CAS No. : 548-62-9

规格 价格 是否有货 数量
10;mM;*;1 mL in DMSO ￥550 In-stock
500 mg ￥350 In-stock
5 g ￥450 In-stock
10 g ￥650 In-stock
50 g ; 询价 ;

* Please select Quantity before adding items.

Crystal Violet 相关产品

bull;相关化合物库:

  • Antibacterial Compound Library
  • FDA Approved amp; Pharmacopeial Drug Library
  • Drug Repurposing Compound Library Plus
  • Clinical Compound Library Plus
  • Bioactive Compound Library Plus
  • Anti-Infection Compound Library
  • Clinical Compound Library
  • Antiviral Compound Library
  • Drug Repurposing Compound Library

生物活性

Crystal violet (Basic Violet 3) is a triarylmethane dye. Crystal Violet (Gentian Violet) has antiviral effects against H1N1 and also has prominent bactericidal activities.

体外研究
(In Vitro)

Crystal violet (Basic Violet 3) is a component of Gram staining that allows one to recognize the difference between gram-positive and gram-negative bacteria with differential staining. The compound helps to access bacterial contamination of tissue culture samples. The staining response is due to the difference in the chemical and structural composition of the cell walls in different bacteria. Crystal Violet can also be used to test the different species of archaea and the cytostatic/cytotoxic effects on tumor cell lines [1][2][3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial

分子量

407.98

Formula

C25H30ClN3
CAS 号

548-62-9
中文名称

结晶紫；龙胆紫；甲基紫
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4deg;C, sealed storage, away from moisture and light

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture and light)
溶解性数据
In Vitro:;

DMSO : ≥ 100 mg/mL (245.11 mM)

H2O : 5 mg/mL (12.26 mM; Need ultrasonic)

* “≥” means soluble, but saturation unknown.

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.4511 mL 12.2555 mL 24.5110 mL
5 mM 0.4902 mL 2.4511 mL 4.9022 mL
10 mM 0.2451 mL 1.2256 mL 2.4511 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Beveridge, T.J. and S. Schultze-Lam, The response of selected members of the archaea to the gram stain. Microbiology, 1996. 142 ( Pt 10): p. 2887-95.

    [2]. Coico, R., Gram staining. Curr Protoc Microbiol, 2005. Appendix 3: p. Appendix 3C.

    [3]. Bil, J., et al., Statins potentiate cytostatic/cytotoxic activity of sorafenib but not sunitinib against tumor cell lines in vitro. Cancer Lett, 2010. 288(1): p. 57-67.

    [4]. Nagayama A. Inactivation of influenza A virus by gentian violet (GV) and GV-dyed cotton cloth, and bactericidal activities of these agents. J Infect Chemother. 2006 Apr;12(2):73-9.

Safranin(Synonyms: Safranin O Basic Red 2)

发表于由

Safranin;(Synonyms: Safranin O; Basic Red 2)

Safranin (Safranin T) 是一种重要且经典的吩嗪染料。Safranin 在学术领域被广泛用作光谱探针和指示剂。Safranin 具有平面结构和阳离子电荷。它可以很容易地插入生物大分子，包括DNA和蛋白质。Safranin 可作为金属离子浓度测定中的氧化还原指示剂。

Safraninamp;;(Synonyms: Safranin O; Basic Red 2)

Safranin Chemical Structure

CAS No. : 477-73-6

规格 价格 是否有货 数量
Free Sample (0.1-0.5 mg) ; Apply now ;
1 g ￥500 In-stock
5 g ￥1500 In-stock
10 g ; 询价 ;
50 g ; 询价 ;

* Please select Quantity before adding items.

Safranin 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus

生物活性

Safranin (Safranin T) is an important and classical phenazinium dye. Safranin has been extensively used in the academic field as a spectroscopic probe and indicator. Safranin possesses a planar structure and cationic charge. It can readily intercalate into biological macromolecules, including DNA and proteins. Safranin can be used as a redox indicator in the determination of metal ion concentration[1].

分子量

350.84

Formula

C20H19ClN4
CAS 号

477-73-6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20deg;C 3 years
4deg;C 2 years
In solvent -80deg;C 6 months
-20deg;C 1 month
溶解性数据
In Vitro:;

DMSO : 25 mg/mL (71.26 mM; ultrasonic and warming and heat to 60°C)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.8503 mL 14.2515 mL 28.5030 mL
5 mM 0.5701 mL 2.8503 mL 5.7006 mL
10 mM 0.2850 mL 1.4252 mL 2.8503 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂：

——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用； 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶

  • 1.

    请依序添加每种溶剂：;10% DMSO ;; 90% (20% SBE-β-CD in saline)

    Solubility: 2.5 mg/mL (7.13 mM); Clear solution; Need ultrasonic

    此方案可获得 2.5 mg/mL (7.13 mM) 的澄清溶液。

    以 1 mL 工作液为例，取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900 μL 20% 的 SBE-β-CD 生理盐水水溶液中，混合均匀。

    将 2 g 磺丁基醚 β-环糊精加入 5 mL 生理盐水中，再用生理盐水定容至 10 mL，完全溶解，澄清透明
*以上所有助溶剂都可在 MCE 网站选购。
参考文献

  • [1]. Wan H, et al. Structure characterization and optical properties investigation of the four main components of the classical phenazinium dye Safranin O. Analyst. 2019;144(24):7149-7156.

FGF-basic 154 (human), (recombinant) 成纤维细胞生长因子碱性154（人），（重组） 品牌：Enzo

发表于由

FGF-basic 154 (human), (recombinant)

成纤维细胞生长因子碱性154（人），（重组）

品牌：Enzo
CAS No.：
储存条件：-20℃
纯度：–
产品编号

(生产商编号)

 等级 规格 运输包装 零售价(RMB) 库存情况 参考值

ALX-201-823-0100

 – 100 µg – 10,980.00 – –


* 干冰运输、大包装及大批量的产品需酌情添加运输费用


* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动，恕不另行通知，确切详情请联系上海金畔生物科技有限公司。

FGF basic (mouse), (recombinant) 成纤维细胞生长因子碱性（小鼠），（重组） 品牌：Enzo

发表于由

FGF basic (mouse), (recombinant)

成纤维细胞生长因子碱性（小鼠），（重组）

品牌：Enzo
CAS No.：
储存条件：-20℃
纯度：–
产品编号

(生产商编号)

 等级 规格 运输包装 零售价(RMB) 库存情况 参考值

ALX-201-824-0100

 – 100 µg – 11,940.00 – –


* 干冰运输、大包装及大批量的产品需酌情添加运输费用


* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动，恕不另行通知，确切详情请联系上海金畔生物科技有限公司。