标签归档：arnicolide

Arnicolide D(Synonyms: 山金车内酯 D)

发表于由

上海金畔生物科技有限公司提供天然产物萜类及其苷类Terpenoids and Glycosides。

Arnicolide D (Synonyms: 山金车内酯 D) 纯度: 99.20%

Arnicolide D 是一种从石胡荽 (Centipeda minima) 中分离出倍半萜内酯。Arnicolide D 调节细胞周期，激活 caspase 信号通路，并抑制 PI3K/AKT/mTOR 和 STAT3 信号通路。Arnicolide D 以剂量和时间依赖性方式显着抑制鼻咽癌 (NPC) 细胞生长。

Arnicolide D(Synonyms: 山金车内酯 D)

Arnicolide D Chemical Structure

CAS No. : 34532-68-8

规格 价格 是否有货 数量
1 mg ￥1900 In-stock
5 mg ￥5710 In-stock
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Arnicolide D 相关产品

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生物活性

Arnicolide D is a sesquiterpene lactone isolated from Centipeda minima. Arnicolide D modulates the cell cycle, activates the caspase signaling pathway and inhibits the PI3K/AKT/mTOR and STAT3 signaling pathways. Arnicolide D inhibits Nasopharyngeal carcinoma (NPC) cell viability in a concentration- and time-dependent manner[1].

IC50 & Target[1]

Caspase

 

PI3K

 

Akt

 

mTOR

 

STAT3

 

分子量

332.39

Formula

C19H24O5
CAS 号

34532-68-8
中文名称

山金车内酯 D
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
参考文献

  • [1]. Liu R, et al. Arnicolide D, from the herb Centipeda minima, Is a Therapeutic Candidate against Nasopharyngeal Carcinoma. Molecules. 2019 May 17;24(10).