NG-Monomethyl-L-arginine Monoacetate NG-单甲基-L-精氨酸醋酸盐品牌：FUJIFILM Wako

发表于2024年9月29日由Whatman官网

NG-Monomethyl-L-arginine Monoacetate

NG-单甲基-L-精氨酸醋酸盐

品牌：FUJIFILM Wako
CAS No.：53308-83-1
储存条件：2-10℃（RT）
纯度：95.0+% (HPLC)

产品编号 (生产商编号)	等级	规格	运输包装	零售价(RMB)	库存情况	参考值
138-11221	for Biochemistry	100 mg	–		–	–

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Hexa-D-arginine TFA(Synonyms: Furin Inhibitor II TFA)

发表于2024年8月31日由Whatman官网

Hexa-D-arginine TFA;(Synonyms: Furin Inhibitor II TFA)

Hexa-D-arginine TFA (Furin Inhibitor II TFA) 是一种稳定的 furin 抑制剂，对 furin，PACE4 和 PC1 的 K_i 值分别为 106 nM，580 nM 和 13.2 μM。Hexa-D-arginine TFA 在体外和体内均可阻断假单胞菌外毒素 A 和炭疽毒素的毒性。

Hexa-D-arginine TFAamp;;(Synonyms: Furin Inhibitor II TFA)

Hexa-D-arginine TFA Chemical Structure

CAS No. : 958204-56-3

规格		是否有货
100 mg	;	询价	;
250 mg	;	询价	;
500 mg	;	询价	;

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Hexa-D-arginine TFA 的其他形式现货产品:

Hexa-D-arginine

生物活性	Hexa-D-arginine TFA (Furin Inhibitor II TFA) is a stable furin inhibitor with K_i values 106 nM, 580 nM and 13.2 μM for furin, PACE4 and prohormone convertase-1 (PC1), respectively. Hexa-D-arginine TFA blocks Pseudomonas exotoxin A and anthrax toxins toxicity in vitro and in vivo^[1]^[2]^[3].
IC₅₀ Target	Ki: 106 nM (Furin), 580 nM (PACE4) and 13.2 μM (PC1)^[3]
体外研究 (In Vitro)	Hexa-D-arginine effectively blocks Pseudomonas aeruginosa exotoxin A (PEA)-induced cell lysis and is itself noncytotoxic^[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究 (In Vivo)	Administration of Hexa-D-arginine (0.1, 1, or 10 nM) to Pseudomonas aeruginosa exotoxin A (PEA)-treated mice (6-week-old FVB and 129/Sv mice) significantly improves their survival rate and also decreases circulating levels of TNF-α^[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量	1068.17
Formula	C₃₈H₇₆F₃N₂₅O₈
CAS 号	958204-56-3
Sequence	Arg-Arg-Arg-Arg-Arg-Arg-NH2
Sequence Shortening	RRRRRR-NH2
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Sarac MS, et al. The furin inhibitor hexa-D-arginine blocks the activation of Pseudomonas aeruginosa exotoxin A in vivo. Infect Immun. 2002 Dec;70(12):7136-9. [2]. Sarac MS, et al. Protection against anthrax toxemia by hexa-D-arginine in vitro and in vivo. Infect Immun. 2004 Jan;72(1):602-5. [3]. Cameron A, et al. Polyarginines are potent furin inhibitors. J Biol Chem. 2000 Nov 24;275(47):36741-9.

Cyclic nona-L-arginine TFA

发表于2024年8月13日由Whatman官网

Cyclic nona-L-arginine TFA;

Cyclic nona-L-arginine TFA 可用于药物转运，其转运速度优于线性分子。

Cyclic nona-L-arginine TFA Chemical Structure

规格		是否有货
100 mg	;	询价	;
250 mg	;	询价	;
500 mg	;	询价	;

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生物活性	Cyclic nona-L-arginine TFA, a nonaarginine peptide used for drug delivery, translocates faster than their linear counterparts^[1].
分子量	1519.69
Formula	C₅₆H₁₀₉F₃N₃₆O₁₁
Sequence Shortening	Cyclic(RRRRRRRRR)
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Yuan Hu, et al. Translocation thermodynamics of linear and cyclic nonaarginine into model DPPC bilayer via coarse-grained molecular dynamics simulation: implications of pore formation and nonadditivity. J Phys Chem B. 2014 Mar 13;118(10):2670-82.

Cyclic nona-L-arginine hydrochloride

发表于2024年7月11日由Whatman官网

Cyclic nona-L-arginine hydrochloride;

Cyclic nona-L-arginine hydrochloride 可用于药物转运，其转运速度优于线性分子。

Cyclic nona-L-arginine hydrochloride Chemical Structure

规格		是否有货
100 mg	;	询价	;
250 mg	;	询价	;
500 mg	;	询价	;

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生物活性	Cyclic nona-L-arginine hydrochloride, a nonaarginine peptide used for drug delivery, translocates faster than their linear counterparts^[1].
分子量	1442.13
Formula	C₅₄H₁₀₉ClN₃₆O₉
Sequence Shortening	Cyclic(RRRRRRRRR)
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Yuan Hu, et al. Translocation thermodynamics of linear and cyclic nonaarginine into model DPPC bilayer via coarse-grained molecular dynamics simulation: implications of pore formation and nonadditivity. J Phys Chem B. 2014 Mar 13;118(10):2670-82.

Hexa-D-arginine(Synonyms: Furin Inhibitor II)

发表于2024年5月9日由Whatman官网

Hexa-D-arginine;(Synonyms: Furin Inhibitor II) 纯度: 99.57%

Hexa-D-arginine (Furin Inhibitor II) 是一种稳定的 furin 抑制剂，对 furin，PACE4 和 PC1 的 K_i 值分别为 106 nM，580 nM 和 13.2 μM。Hexa-D-arginine 在体外和体内均可阻断假单胞菌外毒素 A 和炭疽毒素的毒性。

Hexa-D-arginineamp;;(Synonyms: Furin Inhibitor II)

Hexa-D-arginine Chemical Structure

CAS No. : 673202-67-0

规格	价格	是否有货	数量
1 mg	￥950	In-stock
5 mg	￥3800	In-stock
10 mg	￥6800	In-stock
50 mg	;	询价	;
100 mg	;	询价	;

* Please select Quantity before adding items.

Hexa-D-arginine 相关产品

bull;相关化合物库:

Bioactive Compound Library Plus
Peptide Library

生物活性

Hexa-D-arginine (Furin Inhibitor II) is a stable furin inhibitor with K_i values 106 nM, 580 nM and 13.2 μM for furin, PACE4 and prohormone convertase-1 (PC1), respectively. Hexa-D-arginine blocks Pseudomonas exotoxin A and anthrax toxins toxicity in vitro and in vivo^[1]^[2]^[3].

IC₅₀ Target

Ki: 106 nM (Furin), 580 nM (PACE4) and 13.2 μM (PC1)^[3]

体外研究
(In Vitro)

Hexa-D-arginine effectively blocks Pseudomonas aeruginosa exotoxin A (PEA)-induced cell lysis and is itself noncytotoxic^[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

Administration of Hexa-D-arginine (0.1, 1, or 10 nM) to Pseudomonas aeruginosa exotoxin A (PEA)-treated mice (6-week-old FVB and 129/Sv mice) significantly improves their survival rate and also decreases circulating levels of TNF-α^[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

954.14

Formula

C₃₆H₇₅N₂₅O₆

CAS 号

673202-67-0

Sequence Shortening

RRRRRR-NH2

中文名称

六-D-精氨酸

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Powder	-80deg;C	2 years
	-20deg;C	1 year
In solvent	-80deg;C	6 months
	-20deg;C	1 month

溶解性数据

In Vitro:;

H₂O : 50 mg/mL (52.40 mM; Need ultrasonic)

DMSO : 5 mg/mL (5.24 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	1.0481 mL	5.2403 mL	10.4806 mL
5 mM	0.2096 mL	1.0481 mL	2.0961 mL
10 mM	0.1048 mL	0.5240 mL	1.0481 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

参考文献

[1]. Sarac MS, et al. The furin inhibitor hexa-D-arginine blocks the activation of Pseudomonas aeruginosa exotoxin A in vivo. Infect Immun. 2002 Dec;70(12):7136-9.

[2]. Sarac MS, et al. Protection against anthrax toxemia by hexa-D-arginine in vitro and in vivo. Infect Immun. 2004 Jan;72(1):602-5.

[3]. Cameron A, et al. Polyarginines are potent furin inhibitors. J Biol Chem. 2000 Nov 24;275(47):36741-9.

Vitexin arginine

发表于2024年4月28日由Whatman官网

天然产物黄酮类 Flavonoids

Vitexin arginine

Vitexin arginine 是一种 c-糖基化的黄酮，存在于多种药用植物中，例如榕树 (Ficus deltoid) 和螺旋藻 (Spirodela polyrhiza)。Vitexin arginine 具有广泛的药理作用，包括抗氧化，抗癌，抗炎，抗痛觉过敏和神经保护作用。

Vitexin arginine Chemical Structure

规格		是否有货
5 mg		询价
10 mg		询价
25 mg		询价

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生物活性	Vitexin arginine is a c-glycosylated flavone, and is found in various medicinal plants species such as Ficus deltoid and Spirodela polyrhiza. Vitexin arginine has a wide range of pharmacological effects, including anti-oxidant, anti-cancer, anti-inflammatory, anti-hyperalgesic, and neuroprotective effects^[1]^[2].
体内研究 (In Vivo)	Vitexin exerts neuroprotective effect against pentylenetetrazole-induced seizures, scopolamine-induced memory impairment, and glutamate-induced neuronal excitotoxicity^[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量	606.58
Formula	C₂₇H₃₄N₄O₁₂
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. He M, et al. A review on the pharmacological effects of vitexin and isovitexin. Fitoterapia. 2016 Dec;115:74-85. [2]. Lima LKF, et al. A Brief Review on the Neuroprotective Mechanisms of Vitexin. Biomed Res Int. 2018 Dec 5;2018:4785089.

NG-Nitro-L-arginine Methyl Ester Hydrochloride NG-硝基-L-精氨酸甲酯盐酸盐品牌：FUJIFILM Wako

发表于2024年3月13日由Whatman官网

NG-Nitro-L-arginine Methyl Ester Hydrochloride

NG-硝基-L-精氨酸甲酯盐酸盐

品牌：FUJIFILM Wako
CAS No.：51298-62-5
储存条件：2-10℃
纯度：98.0+% (HPLC)

产品编号 (生产商编号)	等级	规格	运输包装	零售价(RMB)	库存情况	参考值
141-06104	for Biochemistry	1g	–	咨询	–	–

* 干冰运输、大包装及大批量的产品需酌情添加运输费用

NG-Nitro-L-arginine Methyl Ester Hydrochloride NG-硝基-L-精氨酸甲酯盐酸盐品牌：FUJIFILM Wako

发表于2024年2月18日由Whatman官网

NG-Nitro-L-arginine Methyl Ester Hydrochloride

NG-硝基-L-精氨酸甲酯盐酸盐

品牌：FUJIFILM Wako
CAS No.：51298-62-5
储存条件：2-10℃
纯度：98.0+% (HPLC)

产品编号 (生产商编号)	等级	规格	运输包装	零售价(RMB)	库存情况	参考值
147-06101	for Biochemistry	100mg	–	620.00	–	–

* 干冰运输、大包装及大批量的产品需酌情添加运输费用

NG-Nitro-D-arginine Methyl Ester Hydrochloride NG-硝基-D-精氨酸甲酯盐酸盐品牌：FUJIFILM Wako

发表于2024年1月29日由Whatman官网

NG-Nitro-D-arginine Methyl Ester Hydrochloride

NG-硝基-D-精氨酸甲酯盐酸盐

品牌：FUJIFILM Wako
CAS No.：50912-92-0
储存条件：-20℃
纯度：98.0+% (HPLC)

产品编号 (生产商编号)	等级	规格	运输包装	零售价(RMB)	库存情况	参考值
140-06331	for Biochemistry	100 mg	–		–	–

* 干冰运输、大包装及大批量的产品需酌情添加运输费用

NG-Nitro-L-arginine Methyl Ester Hydrochloride NG-硝基-L-精氨酸甲酯盐酸盐品牌：FUJIFILM Wako

发表于2024年1月25日由Whatman官网

NG-Nitro-L-arginine Methyl Ester Hydrochloride

NG-硝基-L-精氨酸甲酯盐酸盐

品牌：FUJIFILM Wako
CAS No.：51298-62-5
储存条件：2-10℃（RT）
纯度：–

产品编号

(生产商编号)

等级

规格

运输包装

零售价(RMB)

库存情况

参考值

143-06103

for Biochemistry

10 g

–

NG-Nitro-L-arginine Methyl Ester Hydrochloride NG-硝基-L-精氨酸甲酯盐酸盐品牌：FUJIFILM Wako

替代品：141-06104

–

* 干冰运输、大包装及大批量的产品需酌情添加运输费用

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标签归档：arginine

NG-Monomethyl-L-arginine Monoacetate NG-单甲基-L-精氨酸醋酸盐品牌：FUJIFILM Wako

NG-Monomethyl-L-arginine Monoacetate

NG-单甲基-L-精氨酸醋酸盐

Hexa-D-arginine TFA(Synonyms: Furin Inhibitor II TFA)

Cyclic nona-L-arginine TFA

Cyclic nona-L-arginine hydrochloride

Hexa-D-arginine(Synonyms: Furin Inhibitor II)

Hexa-D-arginine 相关产品

bull;相关化合物库:

Vitexin arginine

NG-Nitro-L-arginine Methyl Ester Hydrochloride NG-硝基-L-精氨酸甲酯盐酸盐品牌：FUJIFILM Wako

NG-Nitro-L-arginine Methyl Ester Hydrochloride

NG-硝基-L-精氨酸甲酯盐酸盐

NG-Nitro-L-arginine Methyl Ester Hydrochloride NG-硝基-L-精氨酸甲酯盐酸盐品牌：FUJIFILM Wako

NG-Nitro-L-arginine Methyl Ester Hydrochloride

NG-硝基-L-精氨酸甲酯盐酸盐

NG-Nitro-D-arginine Methyl Ester Hydrochloride NG-硝基-D-精氨酸甲酯盐酸盐品牌：FUJIFILM Wako

NG-Nitro-D-arginine Methyl Ester Hydrochloride

NG-硝基-D-精氨酸甲酯盐酸盐

NG-Nitro-L-arginine Methyl Ester Hydrochloride NG-硝基-L-精氨酸甲酯盐酸盐品牌：FUJIFILM Wako

NG-Nitro-L-arginine Methyl Ester Hydrochloride

NG-硝基-L-精氨酸甲酯盐酸盐

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