荧光染料Dye Reagents L-Leucine-7-amido-4-methylcoumarin hydrochloride;(Synonyms: Leu-AMC hydrochloride)
L-Leucine-7-amido-4-methylcoumarin (Leu-AMC) hydrochloride 是 LAP3 c亮氨酸氨基肽酶的蓝色荧光肽基底物。L-Leucine-7-amido-4-methylcoumarin hydrochloride 可用于亮氨酸氨基肽酶抑制实验。
L-Leucine-7-amido-4-methylcoumarin hydrochloride Chemical Structure
CAS No. : 62480-44-8
| 规格 | 是否有货 | ||
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| 100 mg | ; | 询价 | ; |
| 250 mg | ; | 询价 | ; |
| 500 mg | ; | 询价 | ; |
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| 生物活性 |
L-Leucine-7-amido-4-methylcoumarin (Leu-AMC) hydrochloride is a bright blue fluorogenic peptidyl substrate for LAP3 (leucine aminopeptidase). L-Leucine-7-amido-4-methylcoumarin hydrochloride can be used for leucine aminopeptidase inhibition assays in vitro[1]. |
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| 体外研究 (In Vitro) |
In leucine aminopeptidases inhibition assays in KB 3.1 cells. Compounds 3 and 5 are observed to weakly inhibit the biofilm formation by S. aureus and constrain inhibitory activity of ʟ-Leu-AMC hydrolysis in KB 3.1 cells[1].The amount of hydrolyzed 7-amino-4-methylcoumarin (AMC) is determined in a fluorescence spectrophotometer (excitation/emission: 365/440 nm)[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
| 分子量 |
324.80 |
| Formula |
C16H21ClN2O3 |
| CAS 号 |
62480-44-8 |
| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
| 参考文献 |
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