标签归档：abz

Abz-FR-K(Dnp)-P-OH

发表于由

Abz-FR-K(Dnp)-P-OH;

Abz-FR-K(Dnp)-P-OH 是一种血管紧张素转换酶 (ACE) 的底物，是一种用于实时荧光检测的内猝灭荧光底物。

Abz-FR-K(Dnp)-P-OHamp;;

Abz-FR-K(Dnp)-P-OH Chemical Structure

CAS No. : 500799-61-1

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

Abz-FR-K(Dnp)-P-OH is an angiotensin I-converting enzyme (ACE) substrate and an internally quenched fluorogenic substrate for real time fluorescent assay[1].

分子量

831.87

Formula

C39H49N11O10
CAS 号

500799-61-1
Sequence Shortening

Abz-FR-{Lys(Dnp)}-P
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. Alves MF, et al. A continuous fluorescent assay for the determination of plasma and tissue angiotensin I-converting enzyme activity. Braz J Med Biol Res. 2005 Jun;38(6):861-8.

Abz-Ala-Pro-Glu-Glu-Ile-Met-Arg-Arg-Gln-EDDnp 品牌：Peptide

发表于由

Abz-Ala-Pro-Glu-Glu-Ile-Met-Arg-Arg-Gln-EDDnp

品牌：Peptide
CAS No.：824405-61-0
储存条件：-20℃
纯度：–
产品编号

(生产商编号)

 等级 规格 运输包装 零售价(RMB) 库存情况 参考值

332-32301

 – 1mg – 咨询 – –


* 干冰运输、大包装及大批量的产品需酌情添加运输费用


* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动，恕不另行通知，确切详情请联系上海金畔生物科技有限公司。

Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp 品牌：Peptide

发表于由

Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp

品牌：Peptide
CAS No.：1042405-14-0
储存条件：-20℃
纯度：–
产品编号

(生产商编号)

 等级 规格 运输包装 零售价(RMB) 库存情况 参考值

336-32321

 – 1mg – 咨询 – –


* 干冰运输、大包装及大批量的产品需酌情添加运输费用


* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动，恕不另行通知，确切详情请联系上海金畔生物科技有限公司。

Abz-Glu-Pro-Phe-Trp-Glu-Asp-Gln-EDDnp 品牌：Peptide

发表于由

Abz-Glu-Pro-Phe-Trp-Glu-Asp-Gln-EDDnp

品牌：Peptide
CAS No.：534615-70-8
储存条件：-20℃
纯度：–
产品编号

(生产商编号)

 等级 规格 运输包装 零售价(RMB) 库存情况 参考值

339-32311

 – 1mg – 咨询 – –


* 干冰运输、大包装及大批量的产品需酌情添加运输费用


* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动，恕不另行通知，确切详情请联系上海金畔生物科技有限公司。

Abz-FRLKGGAPIKGV-EDDNP TFA

发表于由

Abz-FRLKGGAPIKGV-EDDNP TFA;

Abz-FRLKGGAPIKGV-EDDNP TFA 是一种荧光底物，可测量蛋白酶的酶促活性，例如严重急性呼吸系统综合症冠状病毒 (SARS-CoV) 中的木瓜蛋白酶样蛋白酶 2 (PLP2)。Abz-FRLKGGAPIKGV-EDDNP TFA 具有用于研究 2019-nCoV (COVID-19) 感染的潜力。

Abz-FRLKGGAPIKGV-EDDNP TFAamp;;

Abz-FRLKGGAPIKGV-EDDNP TFA Chemical Structure

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

Abz-FRLKGGAPIKGV-EDDNP TFA is a fluorogenic substrate used to measure the enzymatic activities of protease forms, such as papain-like protease 2 (PLP2) from severe acute respiratory syndrome coronavirus (SARS-CoV). Abz-FRLKGGAPIKGV-EDDNP TFA has the potential for study 2019-nCoV (COVID-19) infection[1].

体外研究
(In Vitro)

Abz-FRLKGGAPIKGV-EDDNP TFA has little fluorescent emission because of the fluorescence resonance energy transfer (FRET) between Abz and EDDNP. The apparent kcat and Km values for this fluorogenic substrate at pH 7.4 are 20 min-1 and 77 µM, respectively. The enhanced fluorescence emission upon substrate cleavage is monitored at the excitation and emission wavelengths of 320 and 420 nm, respectively, in the presence or absence of the chemical compounds assayed[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Sequence Shortening

Abz-FRLKGGAPIKGV-EDDNP
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Yu-San Han, et al. Papain-like Protease 2 (PLP2) From Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV): Expression, Purification, Characterization, and Inhibition. Biochemistry. 2005 Aug 2;44(30):10349-59.