7-Hydroxy-4-coumarinylacetic acid 7-羟基香豆素-4-乙酸品牌：Chemodex

发表于2024年9月23日由Whatman官网

7-Hydroxy-4-coumarinylacetic acid

7-羟基香豆素-4-乙酸

品牌：Chemodex
CAS No.：6950-82-9
储存条件：-20°C
纯度：>98% (NMR)

产品编号 (生产商编号)	等级	规格	运输包装	零售价(RMB)	库存情况	参考值
CDX-H0008-G005	–	5 g	–	1,250.00	–	–

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* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动，恕不另行通知，确切详情请联系上海金畔生物科技有限公司。

7-Hydroxycoumarin-3-carboxylic acid 7-羟基香豆素-3-羧酸品牌：Chemodex

发表于2024年9月21日由Whatman官网

7-Hydroxycoumarin-3-carboxylic acid

7-羟基香豆素-3-羧酸

品牌：Chemodex
CAS No.：779-27-1
储存条件：-20°C
纯度：>98% (TLC)

产品编号 (生产商编号)	等级	规格	运输包装	零售价(RMB)	库存情况	参考值
CDX-H0015-M100	–	100 mg	–	2,480.00	–	–

* 干冰运输、大包装及大批量的产品需酌情添加运输费用

Umbelliferone(Synonyms: 7-羟基香豆素; 7-Hydroxycoumarin; Hydrangin; NSC 19790)

发表于2024年5月16日由Whatman官网

天然产物天然产物苯丙素类 Phenylpropanoids

Umbelliferone (Synonyms: 7-羟基香豆素; 7-Hydroxycoumarin; Hydrangin; NSC 19790) 纯度: 99.14%

Umbelliferone (7-Hydroxycoumarin) 是香豆素家族的天然产物，是一种荧光化合物，可用作防晒剂。

Umbelliferone Chemical Structure

CAS No. : 93-35-6

规格	价格	是否有货
Free Sample (0.1-0.5 mg)		Apply now
10 mM * 1 mL in DMSO	￥550	In-stock
100 mg	￥500	In-stock
200 mg		询价
500 mg		询价

* Please select Quantity before adding items.

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生物活性

Umbelliferone (7-Hydroxycoumarin), a natural product of the coumarin family, is a fluorescing compound which can be used as a sunscreen agent.

IC₅₀ & Target

Human Endogenous Metabolite

分子量

162.14

Formula

C₉H₆O₃

CAS 号

93-35-6

中文名称

7-羟基香豆素

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

溶解性数据

In Vitro:

DMSO : 6.67 mg/mL (41.14 mM; Need ultrasonic)

H₂O : 0.1 mg/mL (0.62 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	6.1675 mL	30.8375 mL	61.6751 mL
5 mM	1.2335 mL	6.1675 mL	12.3350 mL
10 mM	0.6168 mL	3.0838 mL	6.1675 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂：

——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用；以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶

1.

请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% saline

Solubility: ≥ 0.67 mg/mL (4.13 mM); Clear solution

此方案可获得 ≥ 0.67 mg/mL (4.13 mM，饱和度未知) 的澄清溶液。

以 1 mL 工作液为例，取 100 μL 6.7 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中，混合均匀；向上述体系中加入50 μL Tween-80，混合均匀；然后继续加入 450 μL生理盐水定容至 1 mL。

将 0.9 g 氯化钠，完全溶解于 100 mL ddH₂O 中，得到澄清透明的生理盐水溶液
2.

请依序添加每种溶剂： 10% DMSO 90% (20% SBE-β-CD in saline)

Solubility: ≥ 0.67 mg/mL (4.13 mM); Clear solution

此方案可获得 ≥ 0.67 mg/mL (4.13 mM，饱和度未知) 的澄清溶液。

以 1 mL 工作液为例，取 100 μL 6.7 mg/mL 的澄清 DMSO 储备液加到 900 μL 20% 的 SBE-β-CD 生理盐水水溶液中，混合均匀。

将 2 g 磺丁基醚 β-环糊精加入 5 mL 生理盐水中，再用生理盐水定容至 10 mL，完全溶解，澄清透明
3.

请依序添加每种溶剂： 10% DMSO 90% corn oil

Solubility: ≥ 0.67 mg/mL (4.13 mM); Clear solution

此方案可获得 ≥ 0.67 mg/mL (4.13 mM，饱和度未知) 的澄清溶液，此方案不适用于实验周期在半个月以上的实验。

以 1 mL 工作液为例，取 100 μL 6.7 mg/mL 的澄清 DMSO 储备液加到 900 μL玉米油中，混合均匀。

*以上所有助溶剂都可在 MCE 网站选购。

参考文献

[1]. Yu SM, et al. Umbelliferone exhibits anticancer activity via the induction of apoptosis and cell cycle arrest in HepG2 hepatocellular carcinoma cells. Mol Med Rep. 2015 Sep;12(3):3869-3873.

Herniarin(Synonyms: 7-甲氧基香豆素; 7-Methoxycoumarin; Methyl umbelliferyl ether)

发表于2024年5月1日由Whatman官网

天然产物天然产物苯丙素类 Phenylpropanoids

Herniarin (Synonyms: 7-甲氧基香豆素; 7-Methoxycoumarin; Methyl umbelliferyl ether) 纯度: 99.92%

Herniarin 是开花植物中常见的一种天然香豆素类化合物，具有抗肿瘤的作用。

Herniarin Chemical Structure

CAS No. : 531-59-9

规格	价格	是否有货
Free Sample (0.1-0.5 mg)		Apply now
10 mM * 1 mL in DMSO	￥550	In-stock
500 mg	￥500	In-stock
1 g		询价
5 g		询价

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Herniarin 相关产品

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生物活性

Herniarin is a natural coumarin occurs in some flowering plants, with antitumor effect.

体外研究
(In Vitro)

Herniarin is cytotoxic to breast carcinoma cell line MCF-7 with an IC₅₀ of 207.6 µM. Herniarin (100 µM) also induces apoptosis in MCF-7 cells^[1]. Herniarin alone has no obvious cytotoxicity on transitional cell carcinoma (TCC) cells, but when in combination with 5 µg/mL cisplatin, Herniarin (80 µg/mL) potently enhances the antitumor effect of cisplatin, and increases chromatin condensation^[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

176.17

Formula

C₁₀H₈O₃

CAS 号

531-59-9

中文名称

脱肠草素；7-甲氧基香豆素；甲氧基香豆素

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

溶解性数据

In Vitro:

DMSO : ≥ 125 mg/mL (709.54 mM)

* “≥” means soluble, but saturation unknown.

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	5.6763 mL	28.3817 mL	56.7634 mL
5 mM	1.1353 mL	5.6763 mL	11.3527 mL
10 mM	0.5676 mL	2.8382 mL	5.6763 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

参考文献

[1]. Mousavi SH, et al. Comparative analysis of the cytotoxic effect of 7-prenyloxycoumarin compounds and herniarin on MCF-7 cell line. Avicenna J Phytomed. 2015 Nov-Dec;5(6):520-30.

[2]. Haghighitalab A, et al. Enhancement of cisplatin cytotoxicity in combination with herniarin in vitro. Drug Chem Toxicol. 2014 Apr;37(2):156-62.

Cell Assay ^[1]	Briefly, the cells are seeded (10⁴ cells per well) onto flat-bottomed 96-well culture plates and allowed to grow 72 h after treatment with various concentration of auraptene, Herniarin, umbelliferone, and umbelliprenin. After removing the medium, MTT solution (5 mg/mL in PBS) is added and incubated for 4 h and the resulting formazan is solubilized with DMSO (100 mL). The absorption is measured at 570 nm (620 nm as a reference) in an ELISA reader^[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
参考文献	[1]. Mousavi SH, et al. Comparative analysis of the cytotoxic effect of 7-prenyloxycoumarin compounds and herniarin on MCF-7 cell line. Avicenna J Phytomed. 2015 Nov-Dec;5(6):520-30. [2]. Haghighitalab A, et al. Enhancement of cisplatin cytotoxicity in combination with herniarin in vitro. Drug Chem Toxicol. 2014 Apr;37(2):156-62.

Cell Assay
^[1]

Briefly, the cells are seeded (10⁴ cells per well) onto flat-bottomed 96-well culture plates and allowed to grow 72 h after treatment with various concentration of auraptene, Herniarin, umbelliferone, and umbelliprenin. After removing the medium, MTT solution (5 mg/mL in PBS) is added and incubated for 4 h and the resulting formazan is solubilized with DMSO (100 mL). The absorption is measured at 570 nm (620 nm as a reference) in an ELISA reader^[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

参考文献

[1]. Mousavi SH, et al. Comparative analysis of the cytotoxic effect of 7-prenyloxycoumarin compounds and herniarin on MCF-7 cell line. Avicenna J Phytomed. 2015 Nov-Dec;5(6):520-30.

[2]. Haghighitalab A, et al. Enhancement of cisplatin cytotoxicity in combination with herniarin in vitro. Drug Chem Toxicol. 2014 Apr;37(2):156-62.

6-Hydroxycoumarin(Synonyms: 6-羟基香豆素)

发表于2024年4月23日由Whatman官网

天然产物天然产物苯丙素类 Phenylpropanoids

6-Hydroxycoumarin (Synonyms: 6-羟基香豆素) 纯度: 99.14%

6-Hydroxycoumarin 是一种香豆素。香豆素具有抗炎，解热，抗氧化，支气管扩张，血管扩张，抗菌，抗真菌，抑菌和抗肿瘤活性。

6-Hydroxycoumarin Chemical Structure

CAS No. : 6093-68-1

规格	价格	是否有货
100 mg	￥500	In-stock
200 mg		询价
500 mg		询价

* Please select Quantity before adding items.

6-Hydroxycoumarin 相关产品

•相关化合物库:

Natural Product Library Plus
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Traditional Chinese Medicine Monomer Library

生物活性

6-Hydroxycoumarin is a coumarin which has anti-inflammatory, anti-pyretic, anti-oxidant, vasodilator, anti-amoebic, anti-bacterial, anti-fungal, bacteriostatic and antitumor activity^[1].

分子量

162.14

Formula

C₉H₆O₃

CAS 号

6093-68-1

中文名称

6-羟基香豆素

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

溶解性数据

In Vitro:

DMSO : 250 mg/mL (1541.88 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	6.1675 mL	30.8375 mL	61.6751 mL
5 mM	1.2335 mL	6.1675 mL	12.3350 mL
10 mM	0.6168 mL	3.0838 mL	6.1675 mL

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂：

1.

请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% saline

Solubility: ≥ 2.08 mg/mL (12.83 mM); Clear solution

此方案可获得 ≥ 2.08 mg/mL (12.83 mM，饱和度未知) 的澄清溶液。

以 1 mL 工作液为例，取 100 μL 20.8 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中，混合均匀；向上述体系中加入50 μL Tween-80，混合均匀；然后继续加入 450 μL生理盐水定容至 1 mL。

将 0.9 g 氯化钠，完全溶解于 100 mL ddH₂O 中，得到澄清透明的生理盐水溶液
2.

请依序添加每种溶剂： 10% DMSO 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.08 mg/mL (12.83 mM); Clear solution

此方案可获得 ≥ 2.08 mg/mL (12.83 mM，饱和度未知) 的澄清溶液。

以 1 mL 工作液为例，取 100 μL 20.8 mg/mL 的澄清 DMSO 储备液加到 900 μL 20% 的 SBE-β-CD 生理盐水水溶液中，混合均匀。

将 2 g 磺丁基醚 β-环糊精加入 5 mL 生理盐水中，再用生理盐水定容至 10 mL，完全溶解，澄清透明
3.

请依序添加每种溶剂： 10% DMSO 90% corn oil

Solubility: ≥ 2.08 mg/mL (12.83 mM); Clear solution

此方案可获得 ≥ 2.08 mg/mL (12.83 mM，饱和度未知) 的澄清溶液，此方案不适用于实验周期在半个月以上的实验。

以 1 mL 工作液为例，取 100 μL 20.8 mg/mL 的澄清 DMSO 储备液加到 900 μL玉米油中，混合均匀。

*以上所有助溶剂都可在 MCE 网站选购。

参考文献

[1]. Farooq S, et al. Isolation, cytotoxicity evaluation and HPLC-quantification of the chemical constituents from Prangos pabularia. PLoS One. 2014 Oct 14;9(10):e108713.

Coumarin 7(Synonyms: 香豆素7)

发表于2024年4月11日由Whatman官网

Coumarin 7;(Synonyms: 香豆素7)

Coumarin 7 是香豆素激光染料，以糖苷的形式存在于植物中。

Coumarin 7 Chemical Structure

CAS No. : 27425-55-4

规格		是否有货
100 mg	;	询价	;
250 mg	;	询价	;
500 mg	;	询价	;

* Please select Quantity before adding items.

生物活性	Coumarin 7 is a coumarin laser dye in plants in the form of glycosides^[1]^[2].
体外研究 (In Vitro)	Coumarin 7 has the maximum CL intensity (I_max=0.39×10^-9 photon/s•ml), total amount of light (S=0.07×10^-10 photon/ml) and the yield of CL (φ_CL=0.12×10⁸ Einstein/mol)^[2] MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量	333.38
Formula	C₂₀H₁₉N₃O₂
CAS 号	27425-55-4
中文名称	香豆素7
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Sowrirajan Chandrasekaran, et al. Interaction of Coumarin 7 and Coumarin 314 with C-hexylpyrogallol[4]arene. 25 January 2014 [2]. Kazakov DV, et al. Chemiluminescence in the reaction of 1,2,4,5-tetraoxanes with ferrous ions in the presence of xanthene dyes: fundamentals and perspectives of analytical applications. Photochem Photobiol Sci. 2019 May 15;18(5):1130-1137.

7-Hydroxycoumarin-3-carboxylic acid 7-羟基香豆素-3-羧酸品牌：Chemodex

发表于2024年4月3日由Whatman官网

7-Hydroxycoumarin-3-carboxylic acid

7-羟基香豆素-3-羧酸

品牌：Chemodex
CAS No.：779-27-1
储存条件：-20°C
纯度：>98% (TLC)

产品编号 (生产商编号)	等级	规格	运输包装	零售价(RMB)	库存情况	参考值
CDX-H0015-G001	–	1 g	–	13,310.00	–	–

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7,8-Dimethoxycoumarin(Synonyms: 7,8-二甲氧基香豆素)

发表于2024年4月1日由Whatman官网

天然产物天然产物苯丙素类 Phenylpropanoids

7,8-Dimethoxycoumarin (Synonyms: 7,8-二甲氧基香豆素)

7,8-Dimethoxycoumarin (Daphnetin dimethyl ether) 是来自艾蒿 (Artemisia caruifolia) 的一种香豆素类化合物。

7,8-Dimethoxycoumarin Chemical Structure

CAS No. : 2445-80-9

规格	价格	是否有货
5 mg	￥2350	询问价格 & 货期
10 mg	￥4000	询问价格 & 货期

* Please select Quantity before adding items.

生物活性	7,8-Dimethoxycoumarin (Daphnetin dimethyl ether) is a coumarin from Artemisia caruifolia^[1].
分子量	206.19
Formula	C₁₁H₁₀O₄
CAS 号	2445-80-9
中文名称	7,8-二甲氧基香豆素；瑞香素二甲醚
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. NabinC. Barua, et al. Coumarins in artemisia caruifolia. Phytochemistry. 1980,19(10):2217-2218.

7-Benzyloxy-4-trifluoromethycoumarin 7-苄氧基-4-三氟甲基香豆素品牌：Chemodex

发表于2024年3月30日由Whatman官网

7-Benzyloxy-4-trifluoromethycoumarin

7-苄氧基-4-三氟甲基香豆素

品牌：Chemodex
CAS No.：220001-53-6
储存条件：-20°C
纯度：>97% (NMR)

产品编号 (生产商编号)	等级	规格	运输包装	零售价(RMB)	库存情况	参考值
CDX-B0299-M050	–	50 mg	–	3,560.00	–	–

* 干冰运输、大包装及大批量的产品需酌情添加运输费用

7-Benzyloxy-4-trifluoromethycoumarin 7-苄氧基-4-三氟甲基香豆素品牌：Chemodex

发表于2024年3月30日由Whatman官网

7-Benzyloxy-4-trifluoromethycoumarin

7-苄氧基-4-三氟甲基香豆素

品牌：Chemodex
CAS No.：220001-53-6
储存条件：-20°C
纯度：>97% (NMR)

产品编号 (生产商编号)	等级	规格	运输包装	零售价(RMB)	库存情况	参考值
CDX-B0299-M250	–	250 mg	–	10,650.00	–	–

* 干冰运输、大包装及大批量的产品需酌情添加运输费用

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标签归档：香豆素

7-Hydroxy-4-coumarinylacetic acid 7-羟基香豆素-4-乙酸品牌：Chemodex

7-Hydroxy-4-coumarinylacetic acid

7-羟基香豆素-4-乙酸

7-Hydroxycoumarin-3-carboxylic acid 7-羟基香豆素-3-羧酸品牌：Chemodex

7-Hydroxycoumarin-3-carboxylic acid

7-羟基香豆素-3-羧酸

Umbelliferone(Synonyms: 7-羟基香豆素; 7-Hydroxycoumarin; Hydrangin; NSC 19790)

Umbelliferone 相关产品

•相关化合物库:

Herniarin(Synonyms: 7-甲氧基香豆素; 7-Methoxycoumarin; Methyl umbelliferyl ether)

Herniarin 相关产品

•相关化合物库:

6-Hydroxycoumarin(Synonyms: 6-羟基香豆素)

6-Hydroxycoumarin 相关产品

•相关化合物库:

Coumarin 7(Synonyms: 香豆素7)

7-Hydroxycoumarin-3-carboxylic acid 7-羟基香豆素-3-羧酸品牌：Chemodex

7-Hydroxycoumarin-3-carboxylic acid

7-羟基香豆素-3-羧酸

7,8-Dimethoxycoumarin(Synonyms: 7,8-二甲氧基香豆素)

7-Benzyloxy-4-trifluoromethycoumarin 7-苄氧基-4-三氟甲基香豆素品牌：Chemodex

7-Benzyloxy-4-trifluoromethycoumarin

7-苄氧基-4-三氟甲基香豆素

7-Benzyloxy-4-trifluoromethycoumarin 7-苄氧基-4-三氟甲基香豆素品牌：Chemodex

7-Benzyloxy-4-trifluoromethycoumarin

7-苄氧基-4-三氟甲基香豆素

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