ArnicolideC is a sesquiterpene lactone isolated Centipeda minima[1]. ArnicolideC exertes a cytotoxic effect on the panel of Nasopharyngeal carcinoma (NPC) cells, significantly inhibiting cell growth in a dose- and time- dependent manner. ArnicolideC also exhibits inhibitory effects on NPC proliferation[2].
分子量
334.41
Formula
C19H26O5
CAS 号
34532-67-7
中文名称
山金车内酯C
运输条件
Room temperature in continental US; may vary elsewhere.
[1]. Chan CO, et al. Qualitative and quantitative analysis of sesquiterpene lactones in Centipeda minima by UPLC-Orbitrap-MS & UPLC-QQQ-MS. J Pharm Biomed Anal. 2019 May 30;174:360-366.
[2]. Liu R, et al. Arnicolide D, from the herb Centipeda minima, Is a Therapeutic Candidate against Nasopharyngeal Carcinoma. Molecules. 2019 May 17;24(10).
上海金畔生物科技有限公司提供天然产物萜类及其苷类Terpenoids and Glycosides。
Arnicolide D(Synonyms: 山金车内酯 D) 纯度: 99.20%
Arnicolide D 是一种从石胡荽 (Centipeda minima) 中分离出倍半萜内酯。Arnicolide D 调节细胞周期，激活 caspase 信号通路，并抑制 PI3K/AKT/mTOR 和 STAT3 信号通路。Arnicolide D 以剂量和时间依赖性方式显着抑制鼻咽癌 (NPC) 细胞生长。
Arnicolide D Chemical Structure
CAS No. : 34532-68-8
规格
价格
是否有货
数量
1 mg
￥1900
In-stock
5 mg
￥5710
In-stock
10 mg
询价
50 mg
询价
* Please select Quantity before adding items.
Arnicolide D 相关产品
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生物活性
Arnicolide D is a sesquiterpene lactone isolated from Centipeda minima. Arnicolide D modulates the cell cycle, activates the caspase signaling pathway and inhibits the PI3K/AKT/mTOR and STAT3 signaling pathways. Arnicolide D inhibits Nasopharyngeal carcinoma (NPC) cell viability in a concentration- and time-dependent manner[1].
IC50 & Target[1]
Caspase
PI3K
Akt
mTOR
STAT3
分子量
332.39
Formula
C19H24O5
CAS 号
34532-68-8
中文名称
山金车内酯 D
运输条件
Room temperature in continental US; may vary elsewhere.
[1]. Liu R, et al. Arnicolide D, from the herb Centipeda minima, Is a Therapeutic Candidate against Nasopharyngeal Carcinoma. Molecules. 2019 May 17;24(10).
