Darutoside is a diterpenoid isolated from Siegesbeckia[1].
分子量
484.62
Formula
C26H44O8
CAS 号
59219-65-7
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献
[1]. Kim, J.H. Han, et al. Darutoside, a diterpenoid from Siegesbeckia pubescens and its structure revision. Food and Agriculture Organization of the United Nations. 1979.
Polygalasaponin V 是一种从 Polygala japonica 的地上部分分离的三萜皂苷。Polygala japonica 是一种民间药用植物,在中国南方用作祛痰,抗炎,抗菌和抗抑郁药。
Polygalasaponin V Chemical Structure
CAS No. : 162857-65-0
规格
价格
是否有货
5 mg
¥1980
询问价格 货期
10 mg
¥3360
询问价格 货期
20 mg
¥5710
询问价格 货期
* Please select Quantity before adding items.
Polygalasaponin V 相关产品
bull;相关化合物库:
Natural Product Library Plus
Bioactive Compound Library Plus
Immunology/Inflammation Compound Library
Natural Product Library
Glycoside Compound Library
Terpenoids Library
生物活性
Polygalasaponin V is a triterpenoid saponin isolated from the aerial parts of Polygala japonica. Polygala japonica has been a folk medicine herb used as expectorant, anti-inflammatory, antibacterial and antidepressant agents in the south of China[1].
分子量
1223.35
Formula
C58H94O27
CAS 号
162857-65-0
中文名称
瓜子金皂苷 V
运输条件
Room temperature in continental US; may vary elsewhere.
Retrobradykinin has the reverse sequence of Bradykinin (HY-P0206). Retrobradykinin exhibits no kinin activity and can be used as a negative control for Bradykinin[1].
分子量
1060.21
Formula
C50H73N15O11
CAS 号
5991-13-9
Sequence
Arg-Phe-Pro-Ser-Phe-Gly-Pro-Pro-Arg
Sequence Shortening
RFPSFGPPR
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献
[1]. Saul Lande, et al. Retrobradykinin: a Peptide with the Reverse Sequence of Bradykinin. J. Org. Chem. 1962, 27, 12, 4558–4562
(E)-Coniferin is the isomer of Coniferin. Coniferin is a glucoside of coniferyl alcohol. Coniferin inhibits fungal growth and melanization[1].
分子量
342.34
Formula
C16H22O8
CAS 号
124151-33-3
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献
[1]. König S, et al. Soluble phenylpropanoids are involved in the defense response of Arabidopsis against Verticillium longisporum. New Phytol. 2014 May;202(3):823-37.
N-Acetyloxytocin is isolated and characterized in the neurointermediate lobe of the rat pituitary (NIL) and their presence in several brain areas of the rat[1].
体外研究 (In Vitro)
N-Acetyloxytocin is a post-translational modification of vasopressin (VP), and oxytocin (OT). The acetylated forms arc not restricted to the pineal gland, the tissue in which N-Acetyloxytocin is initially identified, but also occur in other systems producing OT and VP[1].
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量
1049.22
Formula
C45H68N12O13S2
CAS 号
10551-48-1
Sequence Shortening
Ac-CYIQNCPLG-NH2 (Disulfide bridge:Cys1-Cys6)
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献
[1]. Liu B, et al. N-acetyl-vasopressin- and N-acetyl-oxytocin-like substances: isolation and characterization in the rat neurointermediate pituitary and presence in the brain. J Neuroendocrinol. 1989;1(1):47-52.
Cortagine is a specific corticotropin-releasing factor receptor subtype 1 (CRF1) agonist with an IC50 of 2.6 nM for rCRF1. Cortagine is an anxiolytic and antidepressive drug in the mouse model[1].
IC50 Target
IC50: 2.6 nM (rCRF1)[1]
体外研究 (In Vitro)
Cortagine inhibits rCRF1 (EC50=0.18 nM) and mCRF2β (EC50=16 nM) in transfected HEK-293 cells[1].
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究 (In Vivo)
Cortagine (30, 100, 300 ng; i.c.v.) significantly decreases the percent time spent in the open arms and number of open arm entries of the elevated plus-maze (EPM) test in nine-week-old male C57BL/6J mice[1].
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量
4442.06
Formula
C192H323N55O63S
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献
[1]. Hossein Tezval, et al. Cortagine, a Specific Agonist of Corticotropin-Releasing Factor Receptor Subtype 1, Is Anxiogenic and Antidepressive in the Mouse Model. Proc Natl Acad Sci U S A. 2004 Jun 22;101(25):9468-73.
C-telopeptide 是一种 I 型胶原蛋白的交联肽,在骨吸收过程中释放,并与骨矿物质密度 (BMD) 相关。
C-telopeptide Chemical Structure
CAS No. : 162929-64-8
规格
价格
是否有货
1 mg
¥1200
询问价格 货期
5 mg
¥4800
询问价格 货期
10 mg
¥8100
询问价格 货期
* Please select Quantity before adding items.
生物活性
C-telopeptide, a cross-linked peptide of type I collagen, is released during bone resorption and has been correlated with bone mineral density (BMD).
体外研究 (In Vitro)
C-telopeptide (C-terminal telopeptide of type 1 collagen, CTx)-a marker for bone resorption. It is a peptide fragment from the carboxy terminal end of the protein matrix; used to monitor anti-resorptive therapies, such as bisphosphonates and hormone replacement therapy, in postmenopausal women and people with low bone mass (osteopenia)
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量
868.90
Formula
C34H56N14O13
CAS 号
162929-64-8
Sequence
Glu-Lys-Ala-His-Asp-Gly-Gly-Arg
Sequence Shortening
EKAHDGGR
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent Solubility
In Vitro:;
H2O
Peptide Solubility and Storage Guidelines:
1.;;Calculate the length of the peptide.
2.;;Calculate the overall charge of the entire peptide according to the following table:
;
Contents
Assign value
Acidic amino acid
Asp (D), Glu (E), and the C-terminal -COOH.
-1
Basic amino acid
Arg (R), Lys (K), His (H), and the N-terminal -NH2
+1
Neutral amino acid
Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q)
0
3.;;Recommended solution:
Overall charge of peptide
Details
Negative (lt;0)
1.;;Try to dissolve the peptide in water first. 2.;;If water fails, add NH4OH (lt;50 μL). 3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0)
1.;;Try to dissolve the peptide in water first. 2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution. 3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0)
1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first. 2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
Asp-Asp-Asp-Asp-Asp is a peptide consists of 5 Asp.
分子量
593.45
Formula
C20H27N5O16
CAS 号
124219-00-7
Sequence
Asp-Asp-Asp-Asp-Asp
Sequence Shortening
DDDDD
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent Solubility
In Vitro:;
H2O
Peptide Solubility and Storage Guidelines:
1.;;Calculate the length of the peptide.
2.;;Calculate the overall charge of the entire peptide according to the following table:
;
Contents
Assign value
Acidic amino acid
Asp (D), Glu (E), and the C-terminal -COOH.
-1
Basic amino acid
Arg (R), Lys (K), His (H), and the N-terminal -NH2
+1
Neutral amino acid
Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q)
0
3.;;Recommended solution:
Overall charge of peptide
Details
Negative (lt;0)
1.;;Try to dissolve the peptide in water first. 2.;;If water fails, add NH4OH (lt;50 μL). 3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0)
1.;;Try to dissolve the peptide in water first. 2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution. 3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0)
1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first. 2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.