天然产物 天然产物苯丙素类 Phenylpropanoids
Psoralen (Synonyms: 补骨脂素; Ficusin) 纯度: 99.92%
Psoralen (Ficusin) 是从补骨脂种子中提取的一种香豆素。Psoralen 具有多种生物学特性,包括抗癌、抗氧化、抗抑郁、抗癌、抗菌、抗病毒等。
Psoralen Chemical Structure
CAS No. : 66-97-7
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Free Sample (0.1-0.5 mg) | Apply now | ||
10 mM * 1 mL in DMSO | ¥605 | In-stock | |
10 mg | ¥550 | In-stock | |
50 mg | ¥1850 | In-stock | |
100 mg | ¥2950 | In-stock | |
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500 mg | 询价 |
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Psoralen 相关产品
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生物活性 |
Psoralen (Ficusin) is a coumarin isolated from the seeds of Fructus Psoraleae. Psoralen exhibits a wide range of biological properties, including anti-cancer, antioxidant, antidepressant, anticancer, antibacterial, and antiviral, et al[1]. |
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体外研究 (In Vitro) |
Psoralen (10-500 μM; 24-48 hours) inhibits cell viability in a concentration- and time-dependent manner in L02 and HepG2 cells. In L02 cells, Psoralen at 400 μM does not significantly change extracellular LDH levels, and 400 μM or 450 μM psoralen inhibits 50–60% of cell viability[1].Psoralen (150-450 μM; 24 hours) induces significant S-phase arrest in L02 cells in time- and dose-dependent manners, but it does not exhibits significant change in the cycle distribution of HepG2 cells[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Cell Proliferation Assay[1]
Cell Cycle Analysis[1]
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体内研究 (In Vivo) |
Psoralen (oral gavage; 17.5 mg/kg; 6 weeks) reduces the number of metastatic lesions and the rate of bone metastasis by 20% compared to vehicle-treated mice. It also reduces tumor infiltration and decreases the percentage of tumor cells in metastatic lesions by ~40% compared to vehicle in mice[2]. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
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Clinical Trial |
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分子量 |
186.16 |
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Formula |
C11H6O3 |
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CAS 号 |
66-97-7 |
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中文名称 |
补骨脂素;补骨脂内酯;补骨酯素 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
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溶解性数据 |
In Vitro:
DMSO : 100 mg/mL (537.17 mM; Need ultrasonic) H2O : 1 mg/mL (5.37 mM; ultrasonic and warming and heat to 80°C) 配制储备液
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
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参考文献 |
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