标签归档：三氟乙酸

Angiopeptin TFA(Synonyms: 血管抑肽三氟乙酸盐)

发表于由

Angiopeptin TFA;(Synonyms: 血管抑肽三氟乙酸盐) 纯度: 99.16%

Angiopeptin TFA 是生长抑素的环状八肽类似物，是一种 sst2/sst5 受体部分激动剂，IC50 值分别为 0.26 nM 和 6.92 nM。Angiopeptin TFA 可以抑制生长激素释放和胰岛素样生长因子-1 (IGF-1) 产生。Angiopeptin TFA 抑制腺苷酸环化酶或刺激细胞外酸化。Angiopeptin TFA 具有用于冠状动脉粥样硬化研究的潜力。

Angiopeptin TFAamp;;(Synonyms: 血管抑肽三氟乙酸盐)

Angiopeptin TFA Chemical Structure

CAS No. : 2478421-60-0

规格 价格 是否有货 数量
5 mg ￥1300 In-stock
10 mg ￥2000 In-stock
25 mg ￥4000 In-stock
50 mg ; 询价 ;
100 mg ; 询价 ;

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Angiopeptin TFA 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus
  • GPCR/G Protein Compound Library
  • Neuronal Signaling Compound Library
  • Anti-Cardiovascular Disease Compound Library
  • Peptide Library

生物活性

Angiopeptin TFA, a cyclic octapeptide analogue of somatostatin, is a weak sst2/sst5 receptor partial agonist with IC50 values of 0.26 nM and 6.92 nM, respectively. Angiopeptin TFA is a potent inhibitor of growth hormone release and insulin-like growth factor-1 (IGF-1) production. Angiopeptin TFA inhibits adenylate cyclase or stimulates extracellular acidification. Angiopeptin TFA has the potential for coronary atherosclerosis research[1][2].

IC50 Target

IC50: 0.26 nM (sst2) and 6.92 nM (sst5)[1][2]
体外研究
(In Vitro)

Angiopeptin (0.1 nM- 10 μM; for 1 h) TFA acts as a partial agonist (pEC50=6.57) with a maximum response of 423% at 3 μM on the release of tritium on CHO hsst2 cells[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究
(In Vivo)

Angiopeptin (20 and 50μg/kg; i.h.) TFA significantly inhibits neointimal formation[1].
Angiopeptin (20 μg/kg; per day) TFA significantly inhibits coronary artery myointimal proliferation in cardiac allografts by appmximalely 50%[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

1326.39

Formula

C58H73F6N11O14S2
CAS 号

2478421-60-0
Sequence Shortening

{Nal}CYWKVCT-NH2
中文名称

血管抑肽三氟乙酸盐
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Sealed storage, away from moisture

Powder -80deg;C 2 years
-20deg;C 1 year

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture)
溶解性数据
In Vitro:;

H2O : 10 mg/mL (7.54 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 0.7539 mL 3.7696 mL 7.5393 mL
5 mM 0.1508 mL 0.7539 mL 1.5079 mL
10 mM — — —

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Lundergan CF, et al. Peptide inhibition of myointimal proliferation by angiopeptin, a somatostatin analogue. J Am Coll Cardiol. 1991;17(6 Suppl B):132B-136B.

    [2]. Alderton F, et al. Somatostatin receptor-mediated arachidonic acid mobilization: evidence for partial agonism of synthetic peptides. Br J Pharmacol. 2001;132(3):760-766.

Endomorphin 2 TFA(Synonyms: 内吗啡肽 2 三氟乙酸盐)

发表于由

Endomorphin 2 TFA (Synonyms: 内吗啡肽 2 三氟乙酸盐) 纯度: 99.55%

Endomorphin 2 TFA，一种高度选择性的高亲和力 μ-opioid 受体激动剂，对 kappa3 结合位点具有高亲和力 ，Ki 为 20 到 30 nM 之间。

Endomorphin 2 TFA (Synonyms: 内吗啡肽 2 三氟乙酸盐)

Endomorphin 2 TFA Chemical Structure

CAS No. : 1276124-00-5

规格 价格 是否有货 数量
10 mM * 1 mL in Water ￥1207 In-stock
5 mg ￥800 In-stock
10 mg ￥1300 In-stock
25 mg ￥2800 In-stock
50 mg   询价  
100 mg   询价  

* Please select Quantity before adding items.

Endomorphin 2 TFA 相关产品

•相关化合物库:

  • Bioactive Compound Library Plus
  • GPCR/G Protein Compound Library
  • Neuronal Signaling Compound Library
  • Neurotransmitter Receptor Compound Library
  • Food-Sourced Compound Library
  • Peptide Library

生物活性

Endomorphin 2 TFA, a high affinity, highly selective agonist of the μ-opioid receptor, displays reasonable affinities for kappa3 binding sites, with Ki value between 20 and 30 nM[1].

IC50 & Target

Ki: 20-30 nM (kappa3 opioid receptor)[1]
分子量

685.69

Formula

C34H38F3N5O7
CAS 号

1276124-00-5
中文名称

内吗啡肽 2 三氟乙酸盐
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶解性数据
In Vitro: 

H2O : 62.5 mg/mL (91.15 mM; Need ultrasonic)

DMSO : 6 mg/mL (8.75 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.4584 mL 7.2919 mL 14.5838 mL
5 mM 0.2917 mL 1.4584 mL 2.9168 mL
10 mM 0.1458 mL 0.7292 mL 1.4584 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Goldberg IE, et al. Pharmacological characterization of endomorphin-1 and endomorphin-2 in mouse brain. J Pharmacol Exp Ther. 1998 Aug;286(2):1007-13.

  • [1]. Goldberg IE, et al. Pharmacological characterization of endomorphin-1 and endomorphin-2 in mouse brain. J Pharmacol Exp Ther. 1998 Aug;286(2):1007-13.

AppliChem A0697.0100 Trifluoroacetic Acid BioChemica 三氟乙酸76-05-1 100 mL

发表于由

上海金畔生物科技有限公司提供AppliChem A0697.0100 Trifluoroacetic Acid BioChemica 三氟乙酸76-05-1 100 mL，欢迎访问官网了解更多产品信息和订购

品牌 货号 产品名称 规格 价格

AppliChem A0697.0100 Trifluoroacetic Acid BioChemica 三氟乙酸76-05-1 100 mL 2005.00

AppliChem A0689.1000 MES anhydrous BioChemica 4432-31-9 1 kg 8404.00

AppliChem A0689.0500 MES anhydrous BioChemica 4432-31-9 500 g 4670.00

AppliChem A0689.0250 MES anhydrous BioChemica 4432-31-9 250 g 3483.00

AppliChem A0676.1000 SDS – Solution 10 % for molecular biology 20% SDS溶液 1 L 1647.00

AppliChem A0675.1000 SDS – Solution 20 % for molecular biology 20% SDS溶液 1 L 2567.00

AppliChem A0666.5000 Uridine BioChemica 尿嘧啶核苷/尿苷 58-96-8 5 kg 0.00

AppliChem A0666.0025 Uridine BioChemica 尿嘧啶核苷/尿苷 58-96-8 25 g 1594.00

AppliChem A0623.0025 Bacitracin BioChemica 枯草杆菌肽 1405-87-4 25 g 2825.00

AppliChem A0622.9010 L-Cystine Dihydrochloride pure L-胱氨酸盐酸盐30925-07-6 10 kg 0.00

AppliChem A0590.1000 Trichloroacetic Acid – Solution 20 % BioChemica 三氯乙酸-20%溶液76-03-9 1 L 842.00

AppliChem A0589.0100 Glutaraldehyde – Solution 25 % for electron microscopy 戊二醛溶液 25%111-30-8 100 mL 1493.00

AppliChem A0585.0500 Pancreatin 胰酶 8049-47-68049-47-6 500 g 3431.00

AppliChem A0585.0100 Pancreatin 胰酶 8049-47-68049-47-6 100 g 745.00

AppliChem A0544.9025 di-Sodium tetraborate anhydrous pure 四硼酸钠1330-43-4 25 g 11961.00

AppliChem A0455.1000 N6-2′-O-Dibutyryl-Adenosine 3′,5′-Cyclophosphate Sodium Salt 1-hydrate 16980-89-5 1 g 22462.00

AppliChem A0427.0100 Safranine O (C.I. 50240) for microscopy 藏红 O 477-73-6 100 g 3853.00

AppliChem A0386.1000 TE buffer (1X) pH 8.0 for molecular biology TE 缓冲液 (1X) pH 8.0 for molecular biology 1 L 684.00

AppliChem A0386.0500 TE buffer (1X) pH 8.0 for molecular biology TE 缓冲液 (1X) pH 8.0 for molecular biology 500 mL 477.00

AppliChem A0385.1000 Acrylamide – Solution (40 %) – Mix 29 : 1 for molecular biology 丙烯酰胺-溶液(40%)- 29：1混合 分子生物学级 1 L 1917.00

N-(6-Aminohexyl)rhodamine 6G-amide bis(trifluoroacetate) N-（6-氨基己基）罗丹明 6G-酰胺（三氟乙酸盐） 品牌：Chemodex

发表于由

N-(6-Aminohexyl)rhodamine 6G-amide bis(trifluoroacetate)

N-（6-氨基己基）罗丹明 6G-酰胺（三氟乙酸盐）

品牌：Chemodex
CAS No.：1140505-40-3
储存条件：-20°C
纯度：>95% (HPCE)
产品编号

(生产商编号)

 等级 规格 运输包装 零售价(RMB) 库存情况 参考值

CDX-R0021-M010

 – 10 mg – 1,250.00 – –


* 干冰运输、大包装及大批量的产品需酌情添加运输费用


* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动，恕不另行通知，确切详情请联系上海金畔生物科技有限公司。

Rhodamine 6G ethylenediamine amide bis (trifluoroacetate) 罗丹明乙二胺酰胺（三氟乙酸盐） 品牌：Chemodex

发表于由

Rhodamine 6G ethylenediamine amide bis (trifluoroacetate)

罗丹明乙二胺酰胺（三氟乙酸盐）

品牌：Chemodex
CAS No.：591742-74-4
储存条件：-20°C
纯度：>95% (HPCE)
产品编号

(生产商编号)

 等级 规格 运输包装 零售价(RMB) 库存情况 参考值

CDX-R0022-M010

 – 10 mg – 1,250.00 – –


* 干冰运输、大包装及大批量的产品需酌情添加运输费用


* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动，恕不另行通知，确切详情请联系上海金畔生物科技有限公司。