[D-Arg25]-Neuropeptide Y (human);
[D-Arg25]-Neuropeptide Y (human) ([D-Arg25] NPY) 是 Y1 受体的选择性激动剂。Neuropeptide Y (human) 和阿尔兹海默症相关,能够保护老鼠皮质神经元对抗淀粉样蛋白毒性。
[D-Arg25]-Neuropeptide Y (human) Chemical Structure
规格 | 是否有货 | ||
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100 mg | ; | 询价 | ; |
250 mg | ; | 询价 | ; |
500 mg | ; | 询价 | ; |
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生物活性 |
[D-Arg25]-Neuropeptide Y (human) ([D-Arg25] NPY) is a Y1 receptor selective agonist. Neuropeptide Y (human) is involved in Alzheimer’s disease (AD) and protects rat cortical neurons against β-Amyloid toxicity[1]. |
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体外研究 (In Vitro) |
[D-Arg25]-NPY (1 μM) reversibly hyperpolarizes the membrane potential of hypocretin cells by 9.9 ± 1.4 mV (data not shown; p < 0.01; n = 10[2]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
体内研究 (In Vivo) |
Intracerebroventricular (icv) administration of [D-Arg25]NPY stimulates food intake in freely-feeding rats[3]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
分子量 |
4271.68 |
Formula |
C189H285N55O57S |
Sequence Shortening |
YPSKPDNPGEDAPAEDMARYYSAL-{D-Arg}-HYINLITRQRY-NH2 |
运输条件 |
Room temperature in continental US; may vary elsewhere. |
储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
参考文献 |
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