Onzigolide(Synonyms: BIM-23A760 TBR-760)

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Onzigolide;(Synonyms: BIM-23A760; TBR-760)

Onzigolide (BIM-23A760)，一种嵌合多巴胺生长抑素化合物，在 DA2 型 (D2R) 和 SST2 型 (SSTR2) 受体。

Onzigolideamp;;(Synonyms: BIM-23A760; TBR-760)

Onzigolide Chemical Structure

CAS No. : 778630-77-6

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生物活性

Onzigolide (BIM-23A760), a chimeric dopamine-somatostatin compound, shows potent agonist activity at both DA type 2 (D2R) and SST type 2 (SSTR2) receptors[1][2].

分子量

1694.20

Formula

C86H116N16O12S4
CAS 号

778630-77-6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Halem HA, et al. TBR-760, a Dopamine-Somatostatin Compound, Arrests Growth of Aggressive Nonfunctioning Pituitary Adenomas in Mice. Endocrinology. 2020 Aug 1;161(8):bqaa101.

    [2]. Cuny T, et al. Characterization of the ability of a, second-generation SST-DA chimeric molecule, TBR-065, to suppress GH secretion from human GH-secreting adenoma cells. Pituitary. 2021 Jun;24(3):351-358.