PEN(mouse) TFA(Synonyms: proSAAS(221-242) TFA)

发表于由

PEN(mouse) TFA;(Synonyms: proSAAS(221-242) TFA)

PEN(mouse) TFA (proSAAS(221-242) TFA) 是一种多肽前体，可用作神经肽。

PEN(mouse) TFAamp;;(Synonyms: proSAAS(221-242) TFA)

PEN(mouse) TFA Chemical Structure

规格 是否有货
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生物活性

PEN(mouse) TFA (proSAAS(221-242) TFA) is the precursor of a number of peptides that function as neuropeptides[1].

分子量

2431.61

Formula

C104H170F3N27O36
Sequence

Ser-Val-Asp-Gln-Asp-Leu-Gly-Pro-Glu-Val-Pro-Pro-Glu-Asn-Val-Leu-Gly-Ala-Leu-Leu-Arg-Val
Sequence Shortening

SVDQDLGPEVPPENVLGALLRV
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. Jonathan H Wardman , et al. ProSAAS-derived Peptides Are Colocalized With Neuropeptide Y and Function as Neuropeptides in the Regulation of Food Intake. PLoS One. 2011;6(12):e28152.