Malantide TFA;
Malantide TFA 是一种合成的十二肽，由被磷酸化酶激酶β亚基上的 PKA 磷酸化的位点衍生而来。Malantide TFA 是 PKA 的高度特异性底物，Km 为 15 μM，并且在各种大鼠组织提取物中显示出 PKI 抑制 > 90％底物磷酸化。Malantide TFA 也是 PKC 的有效底物，Km 为 16 μM。
Malantide TFA Chemical Structure
| 规格 | 是否有货 | ||
|---|---|---|---|
| 100 mg | ; | 询价 | ; |
| 250 mg | ; | 询价 | ; |
| 500 mg | ; | 询价 | ; |
* Please select Quantity before adding items.
Malantide TFA 的其他形式现货产品:
| 生物活性 |
Malantide TFA is a synthetic dodecapeptide derived from the site phosphorylated by cAMP-dependent protein kinase (PKA) on the β-subunit of phosphorylase kinase. Malantide TFA is a highly specific substrate for PKA with a Km of 15 μM and shows protein inhibitor (PKI) inhibition >90% substrate phosphorylation in various rat tissue extracts[1]. Malantide TFA is also an efficient substrate for PKC with a Km of 16 μM[2]. |
IC50 Target |
Km: 15 μM (PKA)[1], 16 μM (PKC)[2], 233 μM (PKG)[1] |
|---|---|
| 体外研究 (In Vitro) |
The Km values of Malantide are 15 μM and 223 μM for PKA and PKG, respectively. The Vmax values are 23.8 units/mg and 6.6 units/mg for for PKA and PKG, respectively[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
| 分子量 |
1747.91 |
| Formula |
C74H125F3N22O23 |
| Sequence |
Arg-Thr-Lys-Arg-Ser-Gly-Ser-Val-Tyr-Glu-Pro-Leu-Lys-Ile |
| Sequence Shortening |
RTKRSGSVYEPLKI |
| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
| 参考文献 |
|