Malantide TFA;
Malantide TFA 是一种合成的十二肽,由被磷酸化酶激酶β亚基上的 PKA 磷酸化的位点衍生而来。Malantide TFA 是 PKA 的高度特异性底物,Km 为 15 μM,并且在各种大鼠组织提取物中显示出 PKI 抑制 > 90%底物磷酸化。Malantide TFA 也是 PKC 的有效底物,Km 为 16 μM。
![Malantide TFA Chemical Structure Malantide TFAamp;;](http://file.medchemexpress.cn/product_pic/hy-p1597a.gif)
Malantide TFA Chemical Structure
规格 | 是否有货 | ||
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100 mg | ; | 询价 | ; |
250 mg | ; | 询价 | ; |
500 mg | ; | 询价 | ; |
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Malantide TFA 的其他形式现货产品:
生物活性 |
Malantide TFA is a synthetic dodecapeptide derived from the site phosphorylated by cAMP-dependent protein kinase (PKA) on the β-subunit of phosphorylase kinase. Malantide TFA is a highly specific substrate for PKA with a Km of 15 μM and shows protein inhibitor (PKI) inhibition >90% substrate phosphorylation in various rat tissue extracts[1]. Malantide TFA is also an efficient substrate for PKC with a Km of 16 μM[2]. |
IC50 Target |
Km: 15 μM (PKA)[1], 16 μM (PKC)[2], 233 μM (PKG)[1] |
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体外研究 (In Vitro) |
The Km values of Malantide are 15 μM and 223 μM for PKA and PKG, respectively. The Vmax values are 23.8 units/mg and 6.6 units/mg for for PKA and PKG, respectively[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
分子量 |
1747.91 |
Formula |
C74H125F3N22O23 |
Sequence |
Arg-Thr-Lys-Arg-Ser-Gly-Ser-Val-Tyr-Glu-Pro-Leu-Lys-Ile |
Sequence Shortening |
RTKRSGSVYEPLKI |
运输条件 |
Room temperature in continental US; may vary elsewhere. |
储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
参考文献 |
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