Bivalirudin

Bivalirudin;

Bivalirudin,一种肽类抗凝剂,是直接凝血酶 (thrombin) 抑制剂,可在侵入性心脏病,特别是在经皮冠状动脉介入中用于抗凝。

Bivalirudinamp;;

Bivalirudin Chemical Structure

CAS No. : 128270-60-0

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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Bivalirudin 的其他形式现货产品:

Bivalirudin TFA

生物活性

Bivalirudin, a peptide anticoagulant, is a direct thrombin inhibitor for anticoagulation in the setting of invasive cardiology, particularly percutaneous coronary intervention[1][2].

体内研究
(In Vivo)

Bivalirudin (2 mg/kg) delays both the time for appearance of first thrombus and the time for occlusion in P2Y12+/+ arteries, although neither prevented vessel occlusion[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial

分子量

2180.29

Formula

C98H138N24O33

CAS 号

128270-60-0

Sequence

{d-Phe}-Pro-Arg-Pro-Gly-Gly-Gly-Gly-Asn-Gly-Asp-Phe-Glu-Glu-ILE-Pro-Glu-Glu-Tyr-Leu

Sequence Shortening

{d-Phe}-PRPGGGGNGDFEEIPEEYL

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Bates ER, et al. Bivalirudin: an anticoagulant option for percutaneous coronary intervention.Expert Rev Cardiovasc Ther. 2004 Mar;2(2):153-62.

    [2]. André P, et al. Anticoagulants (thrombin inhibitors) and aspirin synergize with P2Y12 receptor antagonism in thrombosis.Circulation. 2003 Nov 25;108(21):2697-703.