Orphanin FQ(1-11) TFA

发表于由

Orphanin FQ(1-11) TFA;

Orphanin FQ(1-11) TFA 是孤儿蛋白 FQ 或 nociceptin (OFQ/N) 片段，是一种有效的NOP 受体 (ORL-1; OP4) 激动剂，Ki 为 55 nM。Orphanin FQ(1-11) TFA 对 μ，δ，κ1 和 κ3 受体没有亲和力 (Ki>1000 nM)。Orphanin FQ(1-11) TFA 在 CD-1 小鼠中具有缓解疼痛作用。

Orphanin FQ(1-11) TFAamp;;

Orphanin FQ(1-11) TFA Chemical Structure

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

Orphanin FQ(1-11) TFA, a orphanin FQ or nociceptin (OFQ/N) fragment, is a potent NOP receptor (ORL-1; OP4) agonist, with a Ki of 55 nM. Orphanin FQ(1-11) TFA has no affinity for μ, δ, κ1 and κ3 receptors (Ki>1000 nM). Orphanin FQ(1-11) TFA is analgesic in CD-1 mice[1][2].

分子量

1212.23

Formula

C51H76F3N15O16
Sequence Shortening

FGGFTGARKSA
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Reinscheid RK, et al. Structure-activity relationship studies on the novel neuropeptide orphanin FQ. J Biol Chem. 1996;271(24):14163-14168.

    [2]. Rossi GC, et al. Pharmacological characterization of orphanin FQ/nociceptin and its fragments. J Pharmacol Exp Ther. 1997;282(2):858-865.