LEESGGGLVQPGGSMK TFA

LEESGGGLVQPGGSMK TFA;

LEESGGGLVQPGGSMK TFA,一种蛋白水解肽,是 Infliximab 的一种成分,可用于 Infliximab 的定量分析。Infliximab 是一种与 TNF-α 特异性结合的嵌合单克隆 IgG1 抗体。

LEESGGGLVQPGGSMK TFAamp;;

LEESGGGLVQPGGSMK TFA Chemical Structure

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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LEESGGGLVQPGGSMK TFA 的其他形式现货产品:

LEESGGGLVQPGGSMK acetate

生物活性

LEESGGGLVQPGGSMK TFA, a proteolysis peptide, is a component of Infliximab. LEESGGGLVQPGGSMK TFA can be used for quantitative analysis of Infliximab. Infliximab is a chimeric monoclonal IgG1 antibody that specifically binds to TNF-α[1].

体外研究
(In Vitro)

The anti-TNF antibodies blocking the action of TNF alpha revolutionized therapy of TNF-related diseases such as Inflammatory Bowel Disease, lupus, ulcerative colitis, ankylosing spondylitis, psoriatic arthritis and rheumatoid arthritis. By neutralizing TNF activity, anti-TNF antibodies promote mucosal healing and induce long-term remissions in vivo. The main anti-TNF antibodies that are currently authorized encompass Infliximab, Etanercept, Adalimumab, Certolizumab and Golimumab[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

1659.73

Formula

C66H109F3N18O26S

Sequence Shortening

LEESGGGLVQPGGSMK

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Dorothée LEBERT, et al. A method for quantifying therapeutic antibodies. EP3371592A1.