Argireline acetate;(Synonyms: Acetyl hexapeptide-3 acetate)
Argireline acetate (Acetyl hexapeptide-3 acetate) 是一种无毒,可渗透皮肤的抗皱肽。Argireline acetate 可显着抑制神经肌肉接头处依赖 Ca2+ 的神经递质释放。Argireline acetate 具有抗皱和抗衰老的作用。
Argireline acetate Chemical Structure
规格 | 是否有货 | ||
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100 mg | ; | 询价 | ; |
250 mg | ; | 询价 | ; |
500 mg | ; | 询价 | ; |
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Argireline acetate 的其他形式现货产品:
生物活性 |
Argireline acetate (Acetyl hexapeptide-3 acetate) is a non-toxic, skin-permeable, antiwrinkle peptide. Argireline acetate significantly inhibits Ca2+ dependent neurotransmitter release (acetylcholine) at the neuromuscular junction. Argireline acetate has antiwrinkle and anti-aging activity[1][2][3]. |
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体外研究 (In Vitro) |
The incubation of Argireline solution in different concentrations with human embryonic kidney HEK-293 (IC50 of 34.862 μM) and neuroblastoma IMR-32 cells (IC50 of 68.458 μM)) for 48 h have dose dependent antiproliferative effect. Argireline solution incubated in different concentrations with HSF has a dose-dependent antiproliferative effect on those cells. Cellular proliferation is not effected in Argireline low concentration[2]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
体内研究 (In Vivo) |
Argireline is applied to the aged mice twice daily for 6 weeks. There is an improvement in the histological structure of skin tissue in the aged mice; the amount of type I collagen fibers increased, while that of type III collagen fibers decreased. Argireline could improve the histological structure of skin tissue and rejuvenate the aging skin[3]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
Clinical Trial |
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分子量 |
949.04 |
Formula |
C36H64N14O14S |
Sequence |
N-acetyl-Glu-Glu-Met-Gln-Arg-Arg-NH2 |
Sequence Shortening |
Ac-EEMQRR-NH2 |
中文名称 |
醋酸阿基瑞林 |
运输条件 |
Room temperature in continental US; may vary elsewhere. |
储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
参考文献 |
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