Galanin Receptor Ligand M35 TFA;
Galanin Receptor Ligand M35 TFA 是一种高亲和力的甘丙肽受体 (galanin receptor) 配体 (Kd=0.1 nM)，也是 galanin receptor 拮抗剂。Galanin Receptor Ligand M35 TFA 对人甘丙肽受体 1 型 和 人甘丙肽受体 2 型 的 Ki 值分别为 0.11 nM、2.0 nM。
Galanin Receptor Ligand M35 TFA Chemical Structure
| 规格 | 是否有货 | ||
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| 100 mg | ; | 询价 | ; |
| 250 mg | ; | 询价 | ; |
| 500 mg | ; | 询价 | ; |
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Galanin Receptor Ligand M35 TFA 的其他形式现货产品:
| 生物活性 |
Galanin Receptor Ligand M35 TFA is a high-affinity ligand and antagonist of galanin receptor (Kd=0.1 nM). Galanin Receptor Ligand M35 TFA exerts a Ki values of 0.11 and 2.0 nM for human galanin receptor type 1 and 2, respectively[1][2]. |
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| 体外研究 (In Vitro) |
Galanin Receptor Ligand M35 TFA has a dual effect on the galanin mediated inhibition of Forskolin stimulated cyclic AMP production in Rin m 5F cells. Co-applied with galanin (10 nM), Galanin Receptor Ligand M35 TFA at low concentrations (1 nM) is able to reverse the inhibitory effect of galanin. But when present at higher concentrations (15 and 30 nM), Galanin Receptor Ligand M35 TFA acts as a galanin receptor agonist, inhibiting the forskolin stimulated production of cAMP[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
| 体内研究 (In Vivo) |
Galanin Receptor Ligand M35 TFA (6 nM/10 μL; i.c.v.) improves the ability of the male Sprague-Dnwley rats to acquire the swim maze task[3]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
| 分子量 |
2347.62 |
| Formula |
C109H154N27F3O28 |
| Sequence |
Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-NH2 |
| Sequence Shortening |
GWTLNSAGYLLGPPPGFSPFR-NH2 |
| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
| 参考文献 |
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