PG106

发表于由

PG106;

PG106 是一种有效的、选择性的 hMC3 receptor 拮抗剂 (IC50= 210 nM)，对 hMC4 受体(EC50=9900 nM) 和 hMC5 受体无活性。

PG106amp;;

PG106 Chemical Structure

CAS No. : 944111-22-2

规格 是否有货
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PG106 的其他形式现货产品:

PG106 TFA

生物活性

PG106 is a potent and selective human melanocortin 3 (hMC3) receptor antagonist (IC50=210 nM) and has noactivity at hMC4 receptors (EC50=9900 nM) and hMC5 receptor[1].

IC50 Target

IC50: 210 nM (hMC3 receptor)
EC50: 9900 nM (hMC4 receptor)[1]
分子量

1008.18

Formula

C51H69N13O9
CAS 号

944111-22-2
Sequence Shortening

Ac-{Nle}-D-{Bal}-{D-Nal}-RWK-NH2 (Lactam bridge:Asp2-Lys7)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Paolo Grieco, et al. Further structure-activity studies of lactam derivatives of MT-II and SHU-9119: their activity and selectivity at human melanocortin receptors 3, 4, and 5. Peptides