PUMA BH3 TFA

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PUMA BH3 TFA;

PUMA BH3 (TFA) 是一种 p53 正向凋亡调控因子 (PUMA) BH3 结构域多肽，作为 Bak 的直接激活剂，Kd 值为 26 nM。

PUMA BH3 TFAamp;;

PUMA BH3 TFA Chemical Structure

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生物活性

PUMA BH3 (TFA) is a p53 upregulated modulator of apoptosis (PUMA) BH3 domain peptide, acts as a direct activator of Bak, with a Kd of 26 nM[1].

IC50 Target[1]

Bak

26 nM (Kd)

分子量

3163.32

Formula

C130H203F3N42O45S
Sequence Shortening

EEQWAREIGAQLRRMADDLNAQYER
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Dai H, et al. Evaluation of the BH3-only protein Puma as a direct Bak activator. J Biol Chem. 2014 Jan 3;289(1):89-99.