Gly6(Synonyms: Hexaglycine)

发表于由

Gly6;(Synonyms: Hexaglycine)

Gly6 (Hexaglycine) 是一种具有六个甘氨酸的线性甘氨酸寡肽。

Gly6amp;;(Synonyms: Hexaglycine)

Gly6 Chemical Structure

CAS No. : 3887-13-6

规格 价格 是否有货
5 mg ￥1200 询问价格 货期

* Please select Quantity before adding items.

生物活性

Gly6 (Hexaglycine) is a linear glycine oligopeptide with six glycines[1][2].

体外研究
(In Vitro)

The mode of action of zoocin A against sensitive streptococci is lytic, that lysis occurs as a direct result of the interaction of zoocin A with the cell, and that zoocin A and lysostaphin are both capable of cleaving the peptide substrate Gly6 (Hexaglycine)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

360.32

Formula

C12H20N6O7
CAS 号

3887-13-6
Sequence

Gly-Gly-Gly-Gly-Gly-Gly
Sequence Shortening

GGGGGG
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. R S Simmonds, et al. Mode of Action of a Lysostaphin-Like Bacteriolytic Agent Produced by Streptococcus Zooepidemicus 4881. Appl Environ Microbiol. 1996 Dec;62(12):4536-41.

    [2]. S A Adibi, et al. The Number of Glycine Residues Which Limits Intact Absorption of Glycine Oligopeptides in Human Jejunum. J Clin Invest. 1977 Nov;60(5):1008-16.