Z-YVAD-FMK; 纯度: ge;98.0%
Z-YVAD-FMK 是一种具有细胞通透性 caspase-1 和 caspase-4 抑制剂,具有抗炎和抗肿瘤活性。
Z-YVAD-FMK Chemical Structure
CAS No. : 210344-97-1
规格 | 价格 | 是否有货 | 数量 |
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10;mM;*;1 mL in DMSO | ¥6940 | In-stock | |
1 mg | ¥2200 | In-stock | |
5 mg | ¥5000 | In-stock | |
10 mg | ¥8200 | In-stock | |
50 mg | ; | 询价 | ; |
100 mg | ; | 询价 | ; |
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Z-YVAD-FMK 相关产品
bull;相关化合物库:
- Bioactive Compound Library Plus
- Peptide Library
生物活性 |
Z-YVAD-FMK is a cell-permeable caspase-1 and -4 inhibitor with anti-inflammatory and anti-tumor activities[1]. |
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IC50 Target |
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体外研究 (In Vitro) |
Z-YVAD-FMK (100 μM; 24 hours) significantly downregulated the growth inhibition induced by butyrate in Caco-2 cells[1]. Z-YVAD-FMK (20 μM; pre 1 hour; 24 hours) attenuates the apoptotic induction of III-10 on both HepG2 and BEL-7402 cells, the apoptotic rate of -10 on HepG2 cells is reduced by Z-VAD-FMK from 19.88% to 8.34%, while that on BEL-7402 cells is reduced from 17.56% to 11.98%[4]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Cell Viability Assay[1]
Apoptosis Analysis[1]
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分子量 |
630.66 |
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Formula |
C31H39FN4O9 |
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CAS 号 |
210344-97-1 |
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Sequence |
Z-Tyr-Val-Ala-Asp-FMK |
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Sequence Shortening |
Z-YVAD-FMK |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
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溶解性数据 |
In Vitro:;
DMSO : 125 mg/mL (198.21 mM; Need ultrasonic) 配制储备液
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
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参考文献 |
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