Ac2-26 TFA

Ac2-26 TFA; 纯度: 98.60%

Ac2-26 TFA,是膜联蛋白 A1 (AnxA1) 的活性 N-末端肽,可减轻缺血再灌注诱导的急性肺损伤。Ac2-26 还降低 AnxA1 蛋白表达,抑制受损肺组织中 NF-κB 和 MAPK 通路活化。

Ac2-26 TFAamp;;

Ac2-26 TFA Chemical Structure

规格 价格 是否有货 数量
500 μg ¥2100 In-stock
1 mg ¥3500 In-stock
5 mg ¥9500 In-stock
10 mg ; 询价 ;
50 mg ; 询价 ;

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Ac2-26 TFA 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus
  • Peptide Library

生物活性

Ac2-26 TFA, an active N-terminal peptide of annexin A1 (AnxA1), attenuates ischemia-reperfusion-induced acute lung injury. Ac2-26 also decreases AnxA1 protein expression, inhibits the activation of NF-κB and MAPK pathways in the injured lung tissue[1].

分子量

3203.45

Formula

C143H211F3N32O46S

Sequence Shortening

AMVSEFLKQAWFIENEEQEYVQTVK

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisture and light

Powder -80deg;C 2 years
-20deg;C 1 year

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture and light)

溶解性数据
In Vitro:;

H2O : 0.11 mg/mL (0.03 mM; ultrasonic and adjust pH to 13 with NaOH)

DMSO : < 1 mg/mL (ultrasonic) (insoluble or slightly soluble)

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂:

——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比;如在配制过程中出现沉淀、析出现象,可以通过加热和/或超声的方式助溶

  • 1.

    请依序添加每种溶剂:;PBS

    Solubility: 1 mg/mL (0.31 mM); Clear solution; Need ultrasonic and adjust pH to 9 with NaOH

*以上所有助溶剂都可在 MCE 网站选购。
参考文献
  • [1]. Liao WI, et al. Ac2-26, an Annexin A1 Peptide, Attenuates Ischemia-Reperfusion-Induced Acute Lung Injury. Int J Mol Sci. 2017 Aug 15;18(8). pii: E1771.