TAK-448 acetate;(Synonyms: MVT-602 acetate) 纯度: 99.37
TAK-448 acetate (MVT-602 acetate) 是一种有效的 KISS1R 激动剂,IC50 值为 460 pM,EC50 值为 632 pM。
TAK-448 acetate Chemical Structure
CAS No. : 1470374-22-1
规格 | 价格 | 是否有货 | 数量 |
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1 mg | ¥1500 | In-stock | |
5 mg | ¥4500 | In-stock | |
10 mg | ; | 询价 | ; |
50 mg | ; | 询价 | ; |
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TAK-448 acetate 相关产品
bull;相关化合物库:
- Drug Repurposing Compound Library Plus
- Clinical Compound Library Plus
- Bioactive Compound Library Plus
- Peptide Library
生物活性 |
TAK-448 acetate (MVT-602 acetate) is a potent and full KISS1R agonist with an IC50 of 460 pM and an EC50 of 632 pM[1]. |
IC50 Target |
IC50: 460 pM (KISS1R)[1] |
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体内研究 (In Vivo) |
TAK-448 acetate (0.01-3 mg/kg; given i.h.; dosings on day 0 and 28) has greater anti-tumor effects in VCaP xenograft model[2]. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
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Clinical Trial |
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分子量 |
1285.41 |
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Formula |
C60H84N16O16 |
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CAS 号 |
1470374-22-1 |
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Sequence Shortening |
Ac-{d-Tyr}-{Hyp}-NTF-{Aza-Gly}-L-{Arg(Me)}-W-NH2 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
Sealed storage, away from moisture
*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture) |
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溶解性数据 |
In Vitro:;
DMSO : ≥ 100 mg/mL (77.80 mM) H2O : 50 mg/mL (38.90 mM; Need ultrasonic) * “≥” means soluble, but saturation unknown. 配制储备液
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
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参考文献 |
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