Pam3CSK4 TFA;(Synonyms: Pam3Cys-Ser-(Lys)4 TFA) 纯度: 98.76%
Pam3CSK4 TFA 是一种 Toll 样受体 1/2 (TLR1/2) 激动剂,对人 TLR1/2 的 EC50 为 0.47 ng/mL。
Pam3CSK4 TFA Chemical Structure
CAS No. : 112208-01-2
规格 | 价格 | 是否有货 | 数量 |
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1 mg | ¥1350 | In-stock | |
5 mg | ; | 询价 | ; |
10 mg | ; | 询价 | ; |
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生物活性 |
Pam3CSK4 TFA is a toll-like receptor 1/2 (TLR1/2) agonist with an EC50 of 0.47 ng/mL for human TLR1/2[1]. |
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体外研究 (In Vitro) |
Pam3CSK4 is a TLR1/2 heterodimer recognises triacylated lipopeptides[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
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体内研究 (In Vivo) |
Pam3CSK4 (5 mg/kg; i.p.; once a day for 9 days) alters brain, spleen and liver weights in neonatal mice[3]. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
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分子量 |
1852.33 |
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Formula |
C81H156N10O13S.3C2HF3O2 |
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CAS 号 |
112208-01-2 |
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Sequence |
{Pam3Cys}-Ser-Lys-Lys-Lys-Lys |
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Sequence Shortening |
Pam3C-SKKKK |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
Sealed storage, away from moisture
*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture) |
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溶解性数据 |
In Vitro:;
DMSO : ≥ 50 mg/mL (26.99 mM) * “≥” means soluble, but saturation unknown. 配制储备液
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
*以上所有助溶剂都可在 MCE 网站选购。
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参考文献 |
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