[Des-Arg9]-Bradykinin acetate(Synonyms: [Des-Arg9]-缓激肽醋酸盐)

发表于由

[Des-Arg9]-Bradykinin acetate (Synonyms: [Des-Arg9]-缓激肽醋酸盐) 纯度: 96.90%

[Des-Arg9]-Bradykinin acetate 是缓激肽 B1 受体 (Bradykinin B1 receptor) 激动剂，对 B1 受体的选择性高于 B2 受体。

[Des-Arg9]-Bradykinin acetate (Synonyms: [Des-Arg9]-缓激肽醋酸盐)

[Des-Arg9]-Bradykinin acetate Chemical Structure

CAS No. : 23827-91-0

规格 价格 是否有货 数量
5 mg ￥550 In-stock
10 mg ￥880 In-stock
25 mg ￥1900 In-stock
50 mg   询价  
100 mg   询价  

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[Des-Arg9]-Bradykinin acetate 相关产品

•相关化合物库:

  • Bioactive Compound Library Plus
  • Peptidomimetic Library
  • Peptide Library

生物活性

[Des-Arg9]-Bradykinin acetate is a Bradykinin B1 receptor agonist that displays selectivity for B1 over B2 receptors.

IC50 & Target

Bradykinin B1 receptor[1]
体外研究
(In Vitro)

[Des-Arg9]-Bradykinin acetate is a Bradykinin(B1) receptor agonist. The B2 receptor mediates the action of bradykinin (BK) and lysyl-bradykinin (Lys-BK), the first set of bioactive kinins formed in response to injury from kininogen precursors through the actions of plasma and tissue kallikreins, whereas the B1 receptor mediates the action of [Des-Arg9]-Bradykinin (des-Arg9-BK) and Lys-des-Arg Arg9-BK, the second set of bioactive kinins formed through the actions of carboxypeptidases on BK and Lys-BK, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

964.07

Formula

C46H65N11O12
CAS 号

23827-91-0
Sequence

Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe
Sequence Shortening

RPPGFSPF
中文名称

[Des-Arg9]-缓激肽醋酸盐
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶解性数据
In Vitro: 

H2O : 100 mg/mL (103.73 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.0373 mL 5.1863 mL 10.3727 mL
5 mM 0.2075 mL 1.0373 mL 2.0745 mL
10 mM 0.1037 mL 0.5186 mL 1.0373 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Leeb-Lundberg LM, et al. International union of pharmacology. XLV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences. Pharmacol Rev. 2005 Mar;57(1):27-77.

  • [1]. Leeb-Lundberg LM, et al. International union of pharmacology. XLV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences. Pharmacol Rev. 2005 Mar;57(1):27-77.